Молодежный инновационный вестникМолодежный инновационный вестник2415-7805Федеральное государственное бюджетное образовательное учреждение высшего образования "Воронежский государственный медицинский университет имени Н.Н. Бурденко" Министерства здравоохранения Российской Федерации9963Conference ProceedingsClinical and laboratory characteristics of a series of cases of hepatitis A in childrenLitskevichLizaveta Alexandrovnaelizaveta.litskevich@gmail.comhttps://orcid.org/0009-0007-6578-9718Belarusian state medical university2712202413276781304202412062024Copyright © 2024, Litskevich L.A.2024<p style="text-align: justify;">Introduction. Despite the availability of vaccination against the hepatitis A virus at the present time, as well as the availability of this vaccine in the calendar of Minsk on a free basis, cases of hepatitis A among the child population continue to be registered in the Republic of Belarus. In previous years, isolated cases of hepatitis A among children were registered (the number of hospitalized patients diagnosed with hepatitis A in the Minsk City Children's Infectious Clinical Hospital from 2 to 5 people per year from 2017 to 2023). However, since the beginning of 2024, an increase in the incidence of hepatitis A in children has been recorded. The goal of this study is to analyze the anamnesis, clinical and laboratory data of patients hospitalized at the Minsk City Children's Infectious Clinical Hospital with a diagnosis of hepatitis A since the beginning of 2024. Materials and methods. A retrospective analysis of data from 17 medical records of inpatients who were treated at the Minsk City Children's Infectious Clinical Hospital with a diagnosis of B15.9 (Hepatitis A without hepatic coma) from 01.01.2024 to 03.12.2024 was carried out. The diagnosis was established on the basis of a typical clinical picture of the disease and was confirmed by detecting immunoglobulins M to the hepatitis A virus in the blood serum using ELISA. The data obtained as a result of the study were processed using traditional methods of mathematical statistics using the Statistica 13.0 application program. Results. Data from medical records of inpatients were processed and analyzed, anamnesis data was studied, including epidemiological and vaccination status, the patterns of the course of the disease in patients were determined, and the results of laboratory tests were processed and analyzed. Conclusions. All cases of hepatitis A were reported in unvaccinated children over 7 years of age. With hepatitis A, the typical course is a symptomatic course in the form of a moderate form with the presence of vomiting and fever in the prodromal period. In children over 7 years of age, in most cases, the icteric form develops, with an increase in the biochemical blood test of transaminases, LDH, alkaline phosphatase, GGTP, and in most patients, the presence of bilirubin metabolic products in the urine and hepatomegaly is observed, both by palpation and according to ultrasound data of the BBP. A practicing physician should always remember this diagnosis in his practice, especially when identifying cases of hepatitis in unvaccinated children. In order to prevent cases of hepatitis A, efforts should be intensified to increase the coverage of preventive vaccinations among the population, in particular against the hepatitis A virus.</p> <p></p>hepatitis Achildrenchildhood infectious diseasesгепатит Адетидетские инфекционные болезни1.Инфекционные болезни у детей: учебник / под ред. В.Ф. Учайкина, О.В. Шамшевой. – 3-е изд. – Москва : ГЭОТАР-Медиа, 2021. – 920 с. : ил. – DOI: 10.33029/9704-5654-5-IBD-2021-1-920. ISBN 978-5-9704-5654-5.