<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE root>
<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" article-type="research-article" dtd-version="1.1d1" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher">Молодежный инновационный вестник</journal-id><journal-title-group><journal-title>Молодежный инновационный вестник</journal-title></journal-title-group><issn publication-format="print">2415-7805</issn><publisher><publisher-name>Федеральное государственное бюджетное образовательное учреждение высшего образования "Воронежский государственный медицинский университет имени Н.Н. Бурденко" Министерства здравоохранения Российской Федерации</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">9941</article-id><article-categories><subj-group subj-group-type="heading"><subject>Conference Proceedings</subject></subj-group></article-categories><title-group><article-title>Optimisation of diagnostics and treatment of vascular stiffness and arterial hypertension in patients with acute coronary syndrome against the background of chronic kidney disease</article-title></title-group><contrib-group><contrib contrib-type="author"><name name-style="western"><surname>Leonidova</surname><given-names>Christina Olegovna</given-names></name><email>k_leonidova@list.ru</email><uri content-type="orcid">https://orcid.org/0000-0001-6120-6748</uri><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Pribilova</surname><given-names>Nadezhda Nikolaevna</given-names></name><bio>&lt;p&gt;Doctor of Medical Sciences, Professor&lt;/p&gt;</bio><email>pribylova_nadezda@mail.ru</email><uri content-type="orcid">https://orcid.org/0000-0001-6788-518X</uri><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff id="aff-1">Kursk State Medical University</aff><pub-date date-type="epub" iso-8601-date="2024-12-27" publication-format="electronic"><day>27</day><month>12</month><year>2024</year></pub-date><volume>13</volume><issue>2</issue><fpage>73</fpage><lpage>74</lpage><history><pub-date date-type="received" iso-8601-date="2024-04-08"><day>08</day><month>04</month><year>2024</year></pub-date><pub-date date-type="accepted" iso-8601-date="2024-06-11"><day>11</day><month>06</month><year>2024</year></pub-date></history><permissions><copyright-statement>Copyright © 2024, Leonidova C.O., Pribilova N.N.</copyright-statement><copyright-year>2024</copyright-year></permissions><abstract>&lt;p&gt;Abstract.&lt;/p&gt;&#13;
&lt;p&gt;Introduction. There is a need in clinical medicine to improve diagnostic techniques and evaluate the efficacy of antihypertensive drugs. The aim of the study was to evaluate the efficacy of indapamide and perindopril combination in patients with acute coronary syndrome (ACS) and chronic kidney disease (CKD). Materials and Methods. The following parameters were analysed using volumetric sphygmography on a VS-1500 device: central and peripheral blood pressure (SBPao and PBpao), augmentation index (AI), pulse wave velocity index (PWV) and cardiac ankle vascular index (CAVI). In addition, electrocardiogram, echocardiography, and blood creatinine concentration were studied, and the glomerular filtration rate (GFR) was calculated. Arterial and pulmonary hypertension in patients divided into 3 groups was analysed. Group 1 used perindopril, group 2 used a combination of indapamide and perindopril, and group 3 used perindopril alone. The results show a decrease in SBPao and DBpao, blood creatinine levels, and an increase in GFR during three months of therapy with the indapamide/perindopril combination drug. Conclusions. Noliprel Bi-Forte may be the drug of choice for treatment of this cohort of patients.&lt;/p&gt;</abstract><kwd-group xml:lang="en"><kwd>acute coronary syndrome</kwd><kwd>chronic kidney disease</kwd><kwd>arterial stiffness</kwd><kwd>indapamide/perindopril.</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>острый коронарный синдром</kwd><kwd>хроническая болезнь почек</kwd><kwd>артериальная ригидность</kwd><kwd>индапамид/периндоприл</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Попов, В.В. Особенности полиморбидной патологии у лиц пожилого и старческого</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>возраста с артериальной гипертензией / В. В. Попов, И. А. Новикова, М. В. Трохова //</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Российский кардиологический журн.–2021. №26 (4). – С.18-25.</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>Бойцов, С.А. Современное содержание и совершенствование стратегии высокого сердечно-сосудистого риска в снижении смертности от сердечно-сосудистых заболеваний /С.А. Бойцов, О.М. Драпкина // Терапевтический архив. – 2021. №1. Диагностика и лечение артериальной гипертонии: клин. рекомендации / под ред. И. Е. Чазовой [и др.] // Системные гипертензии. – 2019. № 16 (1). – С.6-31.</mixed-citation></ref></ref-list></back></article>
