Молодежный инновационный вестникМолодежный инновационный вестник2415-7805Федеральное государственное бюджетное образовательное учреждение высшего образования "Воронежский государственный медицинский университет имени Н.Н. Бурденко" Министерства здравоохранения Российской Федерации9836Conference ProceedingsEtiopathogenetic aspects of iron deficiency anemia and its relationship with gestational diabetes mellitusFedotovaEkaterina Igorevnafedotovaekaterina307@mail.ruhttps://orcid.org/0000-0002-2132-9257IvanovViktor Sergeevichviktorivanov28256@icloud.comhttps://orcid.org/0000-0002-1594-9636MakeevaAnna Vitalievna<p>Cand. Sci. (Bio.), Associate Professor of the Department of Pathological Physiology</p>makeeva81@mail.ruhttps://orcid.org/0000-0002-4926-167XYenkovaElena Vladimirovna<p>M.D., Professor, Head of the Department of Obstetrics and Gynecology №2</p>akushervsmabyrdenko@mail.ruhttps://orcid.org/0000-0001-8885-1587ObernikhinKirill Igorevich<p>Assistant of the Department of Operative Surgery with Topographic Anatomy</p>kirill.obernixin@yandex.ruhttps://orcid.org/0000-0001-7385-6211Voronezh State Medical University named after N.N.Burdenko1904202413S13083102102202410042024Copyright © 2024, Fedotova E.I., Ivanov V.S., Makeeva A.V., Yenkova E.V., Obernikhin K.I.2024<p>Introduction. Anemia and gestational diabetes mellitus are the two most common extragenital pathologies, which remain an unexplored topic in the Russian medical healthcare system. One of the reasons for this problem is the insufficient effectiveness of preventive measures for the treatment of anemia in pregnant women. Goal. To assess the relationship between iron deficiency anemia and gestational diabetes mellitus. Materials and methods. An analysis of 100 women in labor with gestational diabetes mellitus was performed, which included a general blood test and a biochemical blood test to determine fasting glucose levels. Results. In 23 (23%) patients, a decrease in hemoglobin levels below 110.0 was detected, which is lower than the reference values of hemoglobin in pregnant women. In 59 (59%) patients, hematocrit was lower than the reference value corresponding to 37%. Anemic syndrome in the first 20 weeks of pregnancy were identified by the attending physician in 23% of patients. After 20 weeks, anemia was detected in 44% of women in labor. Correlation analysis did not reveal a connection between anemia syndrome and gestational diabetes mellitus in pregnant women, however, these pathological conditions continue to occur in a large number of women in labor, leading to difficulties in pregnancy management. Conclusions. Anemia and glycemia are quite common in pregnant women and create some problems during pregnancy and subsequent delivery. In this regard, further study of the interrelationships and pathogenesis of these conditions is required, and there is also a need to confirm the validity of their results in the conditions of the Russian healthcare system.</p>pathogenesisanemiagestational diabetes mellitus.патогенезанемиягестационный сахарный диабет.1.Lin L., Wei Y., Zhu W., Wang C., Su R., Feng H., Yang H. Prevalence, risk factors and associated adverse pregnancy outcomes of anaemia in Chinese pregnant women: a multicentre retrospective study. BMC Pregnancy Childbirth. 2018; 18 (1): 111. DOI: 10.1186/s12884-018-1739-8.2.Абакумова А.А., Куфелкина Т.Ю. Структура анемического синдрома у больных сахарным диабетом 1 типа на фоне беременности. Практическая медицина. 2011; 55 (7): 35–38.3.Ganz T., Olbina G., Girelli D., Nemeth E., Westerman M. Immunoassay for human serum hepcidin. Blood. 2008; 112 (10): 4292–4297. DOI: 10.1182/blood-2008-02-139915.4.Fernández-Real JM, McClain D, Manco M. Mechanisms linking glucose homeostasis and iron metabolism toward the onset and progression of type 2 diabetes. Diabetes Care 2015.5.Andrews NC. Forging a field: the golden age of iron biology. Blood 2008.