Молодежный инновационный вестникМолодежный инновационный вестник2415-7805Федеральное государственное бюджетное образовательное учреждение высшего образования "Воронежский государственный медицинский университет имени Н.Н. Бурденко" Министерства здравоохранения Российской Федерации9808Conference ProceedingsA clinical case of autoimmune polyglandular syndrome. Difficulties in diagnosisEfimenkoDarya Sergeevnf<p>student</p>darya.ef1menko@yandex.ruhttps://orcid.org/0009-0005-3914-6466KlokovaEkaterina Igorevnacaterina.klockowa@yandex.ruhttps://orcid.org/0000-0003-4221-4712KuptsovaGalina Nikolaevna<p>Assistant of the Department of Hospital Therapy and Endocrinology</p>kuptsova-galina.nik@yandex.ruhttps://orcid.org/0000-0002-0530-4594Voronezh State Medical University named after N.N. Burdenko1904202413S11541572102202410042024Copyright © 2024, Efimenko D.S., Klokova E.I., Kuptsova G.N.2024<p>Conduction. Autoimmune polyglandular syndrome (APS) is a combination of two or more autoimmune diseases of the endocrine glands, accompanied by their primary insufficiency, often with autoimmune damage to non-endocrine organs. This article considers a variant of the clinical case of a patient with type 2 APS. Goal. To demonstrate the features of the clinical picture, diagnosis, dynamics and management of a patient with Schmidt syndrome. Materials and methods of research. The study was conducted on the basis of the BUZ in VGKBSMP No. 10, where data from 2 medical records, anamnesis and discharge epicrisis data for the period from 2000-2023, as well as objective data during the last hospitalization of a patient with type 2 autoimmune polyglandular syndrome were studied. Results. The peculiarities of the manifestation of APS include the fact that at first one autoimmune disease develops, and subsequent ones join during life. This study is based on a detailed analysis of the medical history of a patient with autoimmune polyglandular syndrome. Conclusion. In the course of the study, we came to the conclusion that, taking into account two endocrinopathies of an autoimmune nature (chronic adrenal insufficiency and autoimmune thyroiditis), the occurrence and relatively rapid progression of carbohydrate metabolism disorders with the need for an intensified insulin therapy regimen, we can assume the presence of another autoimmune process (LADA diabetes with absolute insulin deficiency). However, taking into account information about a possible overdose of glucocorticoids, an assumption has been made about the medicinal nature of hyperglycemia.</p>autoimmune polyglandular syndromeadrenal insufficiencyhypothyroidismdiabetesаутоиммунный полигландулярный синдромнадпочечниковая недостаточностьгипотиреоздиабет1.Список литературы2.1. Дедов, И. И. Эндокринология: национальное руководство / под ред. И. И. Дедова, Г. А. Мельниченко. - 2-е изд., перераб, и доп. - Москва: ГЭОТАР-Медиа, 2022. - 1112 с. - ISBN 978-5-9704-6751-0.3.2. Schmidt M. B. // Verh. Dtsch. Ges. Pathol. - 1926. - Bd 21. - S. 212-221. Carpenter С. C. J., Solomon N., Silverberg A. et al. // Medicine. - 1964. - Vol. 43. - P. 153-180.4.3. Фадеев В.В., Шевченко И.В., Мельниченко Г.А. Аутоиммунные полигландулярные синдромы. Проблемы Эндокринологии. 1999;45(1):47-54.