Молодежный инновационный вестникМолодежный инновационный вестник2415-7805Федеральное государственное бюджетное образовательное учреждение высшего образования "Воронежский государственный медицинский университет имени Н.Н. Бурденко" Министерства здравоохранения Российской Федерации9336Conference ProceedingsCardiorenal Syndrome in Individuals with Ischemic Heart DiseaseMarchikDarya Aleksandrovna<p>student</p>dashamarchik@gmail.comhttps://orcid.org/0009-0006-3635-5067DruyanLeonid Ibrahimovic<p>Candidate of Medical Sciences</p>mr.Lev-44@yandex.ruhttps://orcid.org/0000-0002-7234-9434Gomel State Medical University1904202413S11031070902202410042024Copyright © 2024, Marchik D.A., Druyan L.I.2024<p>Introduction. Cardiorenal syndrome is a relatively new clinical concept. Research on this syndrome is highly relevant due to its widespread prevalence. The existence of the cardiorenal continuum links the dysfunction of the heart and kidneys. Objective. To identify the presence of cardiorenal syndrome in the studied patients. Materials and Methods. This study analyzed the medical records of inpatients in the cardiology department of the Gomel City Clinical Hospital No. 2. Patients were divided into 3 groups. Indicators of the functional state of the kidneys and the cardiovascular system were analyzed. Statistical analysis of the data was carried out using the "Microsoft Excel 2010" and "STATISTICA 10.0" programs ("StatSoft, Inc"). Results. The appearance of microalbuminuria was noted only in the 3rd group. An assessment of cardiovascular risk was conducted in patients with chronic kidney disease. Statistically significant differences in the studied indicators were found in patients of the 1st and 3rd groups regarding urea (p=0.030), AST (p=0.009), ESR (p=0.011), and CRP (p=0.018). A moderate positive correlation was found between systolic blood pressure and creatine kinase-MB (r=0.50; p=0.05) in patients of the 2nd group, and a high positive correlation between the same indicators (r=0.77; p=0.05) in patients of the 3rd group. Conclusions. Patients with ischemic heart disease and arterial hypertension showed a decrease in glomerular filtration rate, urine density, microalbuminuria, an increase in the concentration of creatinine and urea, indicating the presence of cardiorenal syndrome. According to our data, the greatest severity of this syndrome was observed in patients with arterial hypertension and myocardial infarction.</p>cardiorenalsyndromeischemic heart diseasemicroalbuminuriachronic kidney diseaseкардиоренальныйсиндромИБСмикроальбуминурияХБП1.Кардиоренальный синдром в интенсивной терапии / Н. Т. Ватутин, Г. Г. Тарадин, В. С. Колесников [и др.] // Журнал сердечная недостаточность. – 2016. – Т. 17, № 1(94). – С. 47-56. – DOI 10.18087/rhfj.2016.1.2130. – EDN VPINKR.2.Мацкевич, С. А. Кардиоренальные взаимоотношения / С. А. Мацкевич // Медицинские новости. – 2017. – № 8. – С. 3-6. – EDN ZDUQBJ.3.Медико-социальные аспекты кардиоренального синдрома / И. У. Абдурахманов, Г. К. Жамилова, Г. К. Дуйшеева [и др.] // The Scientific Heritage. – 2021. – № 62-2(62). – С. 29-37. – DOI 10.24412/9215-0365-2021-62-2-29-37. – EDN YKYMIV.4.Сердечно-сосудистый риск и хроническая болезнь почек: стратегии кардио-нефропротекции / В. С. Моисеев, Н. А. Мухин, А. В. Смирнов [и др.] // Клиническая фармакология и терапия. – 2014. – Т. 23, № 3. – С. 4-27. – EDN TCUNBT.5.Григорян, С. В. Сравнительная оценка маркеров воспаления и фиброза у больных с различными клиническими формами фибрилляции предсердий / С. В. Григорян, Л. Г. I. Азарапетян, К. Г. Адамян // Кардиоваскулярная терапия и профилактика. – 2018. – Т. 17, № 6. – С. 26-31. – DOI 10.15829/1728-8800-2018-6-26-31. – EDN YPXLCH.