Молодежный инновационный вестникМолодежный инновационный вестник2415-7805Федеральное государственное бюджетное образовательное учреждение высшего образования "Воронежский государственный медицинский университет имени Н.Н. Бурденко" Министерства здравоохранения Российской Федерации9232Conference ProceedingsDeformation of mental disorders in the misuse of synthetic cannabinoidsSelivanovGeorgy Yurievich<p>Candidate of Medical Sciences, Senior Researcher, Department of Addictive States, Associate Professor, Department of Pedagogy and Psychology of Extreme Situations, psychiatrist, narcologist, psychotherapist</p>gergy89selivanov@gmail.comhttps://orcid.org/0000-0002-8555-3987OtmakhovAndrey Pavlovich<p>head doctor</p>otmakhov_a@mail.ruhttps://orcid.org/0000-0002-1082-2388SorokinaAnna Veniaminovna<p>doctor: psychiatrist, narcologist, psychotherapist of the psychiatric department</p>annaanais260@gmail.comBokhanNikolai Aleksandrovich<p>Academician of the Russian Academy of Sciences, Doctor of Medical Sciences, Director of the Mental Health Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences</p>niipzso@gmail.comhttps://orcid.org/0000-0002-1052-855XSaint Petersburg University of State Fire Service of Emercom of RussiaPsychiatric Hospital of St. Nicholas the ChudotvorcaMnukhin S.S. Rehabilitation Treatment Center “Child Psychiatry”Mental Health Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences"Psychiatric Hospital of St. Nicholas the Chudotvorca"1904202413S14624630701202410042024Copyright © 2024, Selivanov G.Y., Otmakhov A.P., Sorokina A.V., Bokhan N.A.2024<p>Introduction. Since the early 2000s, psychiatrists and narcologists in Russia and Europe began to notice an increase in the number of mental disorders associated with the use of synthetic cannabinoids (SC). Our and other studies have previously shown that the use of this drug contributes to the onset of acute psychotic states and in certain cases may be a factor contributing to the development of schizophrenia. The impact of synthetic cannabinoids on mental disorders is still poorly understood and remains a pressing issue to this day. Target. studying the phenomenon of deformation of mental disorders due to the abuse of synthetic cannabinoids. Materials and methods. 285 men were examined: 235 with addiction to SC (F12.2), (of which 97 were diagnosed with personality and behavioral disorders in adulthood (F60.xxF62.xx), 139 with schizophrenia F20.xx), as well as 50 people with schizophrenia without substance abuse or dependence. The study took place on the basis of psychiatric institutions in the Tomsk region (SibiFNKTs, Seversk; Research Institute of PZ, TKPB, SSMP, Tomsk), St. Petersburg (PND No. 5, PB No. 2") and Nizhnevartovsk (NPNB), Noyabrsk (NPND). Methods. Follow-up, clinical-psychopathological (PANS, SANS, CGI, MMPI), statistical (SPSS, Python). Results. SCs can initiate a state of intoxication, contributing to the occurrence of psychotic episodes and serve as a trigger for the development of schizophrenia. There are four types of drug intoxication: delusional, schizophrenic, with pseudohallucinations and delirious. The personality traits of patients dependent on SC are directly related to such manifestations as emotional instability, rigidity, introversion and a tendency to deviant behavior. Characteristics of nonconformist personality disorder patients who abuse drugs include disorganization, conflict, unpredictability, spontaneity, frivolity, impulsiveness, and non-compliance with rules and regulations. The use of SC can smooth out the negative symptoms of schizophrenia and cause an exacerbation of exogenous psychoproductive symptoms; it can also shorten the period of drug addiction formation and introduce new symptoms associated with withdrawal syndrome. Patients with schizophrenia who abuse SC do not experience an emotional defect, showing emotionality and a desire to communicate. Conclusions. The phenomenon of SC abuse has become one of the main factors contributing to the emergence of distorted mental disorders. In the clinical picture of exacerbations of schizophrenia, stable exogenous threatening illusory, hallucinatory, and delirious perception disorders are observed. In a state of remission of schizophrenia, the ability to adapt to social and professional environments, mainly associated with addiction and the criminal sphere, is surprisingly revealed. However, the stigmatizing feature here is the predominance of volitional disorders, which manifest themselves in emotional apathy, as well as in frequent cases of rehospitalization not directly related to drug addiction. Patients suffering from schizophrenia and personality disorders have behavioral disorders characterized by a tendency to crime, rejection of society, a desire for isolation in their addictive environment, as well as increased suspicion and suspiciousness. In people with a personality disorder, actual schizophrenic behavior can be noted.</p>synthetic cannabinoidsaddictionabuseschizophreniapersonality disorderscomorbidityсинтетические каннабиноидызависимостьзлоупотреблениешизофрениярасстройства личностикоморбидность<p>Introduction. Since the early 2000s, psychiatrists and narcologists in Russia and Europe began to notice an increase in the number of mental disorders associated with the use of synthetic cannabinoids (SC). Our and other studies have previously shown that the use of this drug contributes to the onset of acute psychotic states and in certain cases may be a factor contributing to the development of schizophrenia. The impact of synthetic cannabinoids on mental disorders is still poorly understood and remains a pressing issue to this day. Target. studying the phenomenon of deformation of mental disorders due to the abuse of synthetic cannabinoids. Materials and methods. 285 men were examined: 235 with addiction to SC (F12.2), (of which 97 were diagnosed with personality and behavioral disorders in adulthood (F60.xxF62.xx), 139 with schizophrenia F20.xx), as well as 50 people with schizophrenia without substance abuse or dependence. The study took place on the basis of psychiatric institutions in the Tomsk region (SibiFNKTs, Seversk; Research Institute of PZ, TKPB, SSMP, Tomsk), St. Petersburg (PND No. 5, PB No. 2") and Nizhnevartovsk (NPNB), Noyabrsk (NPND). Methods. Follow-up, clinical-psychopathological (PANS, SANS, CGI, MMPI), statistical (SPSS, Python). Results. SCs can initiate a state of intoxication, contributing to the occurrence of psychotic episodes and serve as a trigger for the development of schizophrenia. There are four types of drug intoxication: delusional, schizophrenic, with pseudohallucinations and delirious. The personality traits of patients dependent on SC are directly related to such manifestations as emotional instability, rigidity, introversion and a tendency to deviant behavior. Characteristics of nonconformist personality disorder patients who abuse drugs include disorganization, conflict, unpredictability, spontaneity, frivolity, impulsiveness, and non-compliance with rules and regulations. The use of SC can smooth out the negative symptoms of schizophrenia and cause an exacerbation of exogenous psychoproductive symptoms; it can also shorten the period of drug addiction formation and introduce new symptoms associated with withdrawal syndrome. Patients with schizophrenia who abuse SC do not experience an emotional defect, showing emotionality and a desire to communicate. Conclusions. The phenomenon of SC abuse has become one of the main factors contributing to the emergence of distorted mental disorders. In the clinical picture of exacerbations of schizophrenia, stable exogenous threatening illusory, hallucinatory, and delirious perception disorders are observed. In a state of remission of schizophrenia, the ability to adapt to social and professional environments, mainly associated with addiction and the criminal sphere, is surprisingly revealed. However, the stigmatizing feature here is the predominance of volitional disorders, which manifest themselves in emotional apathy, as well as in frequent cases of rehospitalization not directly related to drug addiction. Patients suffering from schizophrenia and personality disorders have behavioral disorders characterized by a tendency to crime, rejection of society, a desire for isolation in their addictive environment, as well as increased suspicion and suspiciousness. In people with a personality disorder, actual schizophrenic behavior can be noted.</p>