Молодежный инновационный вестникМолодежный инновационный вестник2415-7805Федеральное государственное бюджетное образовательное учреждение высшего образования "Воронежский государственный медицинский университет имени Н.Н. Бурденко" Министерства здравоохранения Российской Федерации9186Conference ProceedingsIdentification of a tendency to a violation of the hemostasis system among students of N.N. Burdenko VSMUBatishchevMikhail Evgenyevichmr.foxm43@yandex.comhttps://orcid.org/0009-0008-3814-9624GrebennikovaIrina Valerievna<p>Candidate of Medical Sciences, Associate Professor of the Department of Pathological Physiology</p>irina_voronezh@inbox.ruhttps://orcid.org/0000-0003-0213-9383LushchikMarina Valerievna<p>Candidate of Biological Sciences, Associate Professor of the Department of Pathological Physiology</p>marleven@mail.ruhttps://orcid.org/0000-0002-1273-8374Voronezh state Medical University named after N. N. Burdenko1904202413S12872902912202310042024Copyright © 2024, Batishchev M.E., Grebennikova I.V., Lushchik M.V.2024<p>Introduction. There are few data in the literature on the prevalence of various hemostasis disorders in the population. Goal. To determine the propensities to hemostasis disorders among medical university students. Materials and methods. Questionnaire and subsequent analysis of capillary blood on a coagulometer. Statistical processing was carried out using Microsoft Exel 2016 software. 111 people aged 18 to 22 years (24 men and 87 women) took part in the survey. Results. It was revealed that among the surveyed students, 90% (n=100) have some degree of risk for hypocoagulation and 10% (n=11) have a tendency to hypercoagulation. Women were more likely to have a predisposition to hypocoagulation (%n), and men were more likely to have hypercoagulation (%n). A positive correlation was found between the presence of disorders in the hemostasis system and diseases of the cardiovascular system in relatives (r=0.997, p0.05) and chronic inflammatory diseases in the respondents (r=0.985, p0.05). The most common symptoms of hypocoagulation were nasal and gingival bleeding (45%, n=50). Low levels of INR (12%, n=1) and prothrombin time (25%, n=2) were found in individuals with a tendency to hypercoagulation. Conclusions. Identification of the most common symptoms of hemostasis disorders, the presence in the anamnesis of diseases of the cardiovascular system in relatives and chronic inflammatory diseases in the respondents, changes in the coagulogram will allow to establish a tendency to hemostasis disorders.</p>hemorrhagic diseaseshypocoagulationhypercoagulationquestionnaireexpress coagulometerгеморрагические заболеваниягипокоагуляциягиперкоагуляцияанкетированиеэкспресс-коагулометр1.Распространенность геморрагических проявлений у московских детей школьного возраста / П. В. Свирин [и др.] // Педиатрия. Журнал им. Г.Н. Сперанского. – 20109. – Т. 90, № 4. – С. 43-47.2.Von Willebrand Disease Epidemiology, Burden of Illness and Management: A Systematic Review / Р. Du [et al.]. J Blood Med. – 2023. – Vol. 14. – P. 189-2083.Сырых Е. А. Распространенность гемофильных артропатий у детей с гемофилией Воронежской области в зависимости от различных факторов / Е. А. Сырых, С. Н. Алыева, О. А. Кучер // Молодежный инновационный вестник. – 2022. – Т. 11, № S1. – С. 358-362.4.Ковалев, М. C. Патогенетические основы гипокоагуляции / М. C. Ковалев, В.Р. Майриков, И.В. Гребенникова // Международный студенческий научный вестник. – 2016. – № 4-2. – С. 151-152.5.Анализ протромботического полиморфизма генов свертывающейся системы крови у детей, перенесших тромбозы / Н. В. Малюжинская, М. А. Моргунова, И. В. Петрова [и др.] // Международный научно-исследовательский журнал. – 2018. – № 10-2(76). – С. 29-31. – DOI 10.23670/IRJ.2018.76.10.030. – EDN VKHGSM.6.Момот, А. П. Проблема тромбофилии в клинической практике / А. П. Момот // Российский журнал детской гематологии и онкологии. – 2015. – Т. 2, № 1. – С. 36-48. – DOI 10.17650/2311-1267-2015-1-36-48. – EDN TWITAV.7.Особенности нарушений системы гемостаза при COVID-19 у детей (обзор литературы) / М. В. Гомелля [и др.] // Acta Biomedica Scientifica (East Siberian Biomedical Journal). – 2021. – Т. 6, № 3. – С. 142-153.8.Galstyan G.M. Coagulopathy in COVID-19 / G.M. Galstyan // Pulmonologiya. – 2020. – Vol. 30, No. S5. – P. 645-657.9.Hoppe B. Coagulation and the fibrin network in rheumatic disease: a role beyond haemostasis / B. Hoppe, T. Dörner // Nat Rev Rheumatol. – 2012. –№8(12). – Р. 738-746. doi: 10.1038/nrrheum.2012.184.10.Gear A.R. Platelet chemokines and chemokine receptors: linking hemostasis, inflammation, and host defense / A.R. Gear, D. Camerini // Microcirculation 2003. – Vol. 10(3-4). – P. 335-350. doi: 10.1038/sj.mn.7800198.