Молодежный инновационный вестникМолодежный инновационный вестник2415-7805Федеральное государственное бюджетное образовательное учреждение высшего образования "Воронежский государственный медицинский университет имени Н.Н. Бурденко" Министерства здравоохранения Российской Федерации8875Conference ProceedingsTHE ROLE OF E-CADHERIN IN THE PROGNOSIS OF THYROID CANCER RECURRENCEAtadzhanovIlyas Borisovichatadzanov.ilyas@yandex.ruhttps://orcid.org/0000-0003-1995-2661ShestakovaValeriya Gennadievnashestvg@mail.ruhttps://orcid.org/0000-0003-1136-7396NigmatullinaLeila Ildarovnaleila.nigmatullina@gmail.comhttps://orcid.org/0000-0002-1598-9638Tver State Medical University2903202312111121704202304062023Copyright © 2023, Atadzhanov I.B., Shestakova V.G., Nigmatullina L.I.2023<p style="text-align: justify;">The aim of the study was to clarify the role of E-cadherin expression in thyroid tumor tissue samples and to determine the possibility of making a prognosis for cancer recurrence. Materials and methods. Human tumor tissue samples were examined by histological and immunohistochemical methods. Results. A significant decrease in the expression of E-cadherin was found in 1/3 of cases of papillary thyroid cancer. The preservation of E-cadherin expression in follicular cancer has also been established.</p>thyroidcancerhistologyimmunohistochemistryE-cadherinщитовидная железаракгистологияиммуногистохимияЕ-кадгерин[Shah JP. Thyroid carcinoma: epidemiology, histology, and diagnosis. Clin Adv Hematol Oncol. 2015 Apr;13(4 Suppl 4):3-6][Pellegriti G, Frasca F, Regalbuto C, Squatrito S, Vigneri R. Worldwide increasing incidence of thyroid cancer: update on epidemiology and risk factors. J Cancer Epidemiol. 2013;2013:965212][Li Z, Yin S, Zhang L, Liu W, Chen B. Prognostic value of reduced E-cadherin expression in breast cancer: a meta-analysis. Oncotarget. 2017 Mar 7;8(10):16445-16455]