Молодежный инновационный вестник

2415-7805

Федеральное государственное бюджетное образовательное учреждение высшего образования "Воронежский государственный медицинский университет имени Н.Н. Бурденко" Министерства здравоохранения Российской Федерации

8824

Conference Proceedings

PREVALENCE AND STRUCTURE OF CARDIOVASCULAR COMPLICATIONS OF A NEW CORONAVIRUS INFECTION IN PATIENTS WHO HAVE SUFFERED AN ISCHEMIC STROKE

Pershina

Diana Evgenevna

dianapershina2000@gmail.comhttps://orcid.org/0000-0003-3202-4579

Siberian State Medical University

29032023

121119121

16042023

2023

<p style="text-align: justify;">A significant increase in cardiovascular morbidity in 2020-2022 is objectively associated with COVID-19, which is characterized not only by a pandemic level of prevalence, the development of severe and fatal complications in a large percentage of cases, but also by a variety of changes from different body systems, including cardiovascular complications that occur both in acute and post-acute period. The aim of the work was to study the prevalence and structure of cardiovascular complications of COVID-19 in patients who have suffered an ischemic stroke. Data from the BARS medical electronic system of 109 patients who suffered an ischemic stroke in the middle cerebral artery basin were analyzed. A search was conducted for patients who underwent COVID-19 in the period from April 2020 to December 2022, as a result of which 33 patients were identified who met this criterion. Distribution of patients by gender: 14 (42%) women (average age 70 (56;85) years) and 19 (58%) men (average age - 63 (53;75) years). Acute complications included myocardial infarction, venous and arterial embolism, newly diagnosed heart failure or decompensation of previously existing heart failure, repeated ischemic stroke detected within 4 weeks after confirmation of COVID-19. As a result, which were detected in patients, but already in the post-ovoid period (more than 4 weeks later). Analysis of the data obtained indicates that in the acute period in 3 patients (9%; 2 women and 1 man) were diagnosed with: myocardial infarction, embolism of the arteries of the lower extremities, heart failure. Two of these patients underwent inpatient treatment according to clinical recommendations, the severity of COVID-19 was assessed as moderate and severe; the development of severe pneumonia complicated by respiratory failure was noted in both cases. The development of myocardial infarction in one patient led to a fatal outcome, and the course of COVID-19 in this case was characterized as mild and the patient did not receive treatment at the outpatient stage. In the long-term period, 4 patients (12%; 3 women and 1 man) had newly diagnosed heart failure (2 patients), myocardial infarction (2 patients), repeated ischemic stroke in the BBA (1 patient). Two of these patients suffered COVID-19 easily and received outpatient treatment, while the rest were treated in a hospital, the course of COVID-19 was characterized as moderate severity and was accompanied by the development of severe pneumonia complicated by respiratory failure. The development of such a variety of cardiovascular manifestations in COVID-19 may be due to the presence of interrelated pathogenesis links, such as endothelial dysfunction, coagulopathy, systemic inflammation and hypoxia.</p>

cardiovascular complicationsCOVID-19ischemic stroke

cердечно-сосудистые осложненияСОVID-19ишемический инсульт

Кукес И.В., Салмаси Ж.М., Терновой К.С., Казимирский А.Н., Ободзинская Т. Е., Лим В.Г., Глаговский П.Б., Мамедов И. С., Порядин Г.В., Савичева А. С., Кукес Е.А., Птицын М. С., Андреев А. Д. Предпосылки к созданию атласа постковидного воспаления как способа персонализированной фармакотерапии, а также прогнозирования и предупреждения органных и системных дисфункций. Медицинский совет. 2021;(12):72–88. https://doi.org/10.21518/2079-701X-2021-12-72-88.

Guo T, Fan Y, Chen M, et al. Cardiovascular Implications of Fatal Outcomes of Patients with Coronavirus Disease 2019 (COVID-19). JAMA Cardiol. 2020; e201017. doi:10.1001/jamacardio.2020.1017

Bikdeli B, Madhavan M, Jimenez D, et al. COVID-19 and Thrombotic or Thromboembolic Disease: Implications for Prevention, Antithrombotic Therapy, and Follow-up. J Am Coll Cardiol. 2020 Apr 17. doi: 10.1016/jjacc.2020.04.031