Молодежный инновационный вестник

2415-7805

Федеральное государственное бюджетное образовательное учреждение высшего образования "Воронежский государственный медицинский университет имени Н.Н. Бурденко" Министерства здравоохранения Российской Федерации

8368

Unclassified

EFFECT OF THE PULMONARY REHABILITATION ON THE COURSE OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE IN PATIENTS WITH METABOLIC SYNDROME

Pertsev

Alexander V.

pertsev.vrn@yandex.ruhttps://orcid.org/0000-0001-8984-1831Glavatskikh

Yuliya О.

Yuliyag36@gmail.comhttps://orcid.org/0000-0002-2398-5987

Voronezh State Medical University named after N. N. Burdenko

20042023

12S2654655

14022023

06042023

2023

The course of chronic obstructive pulmonary disease (COPD) is often caused by metabolic syndrome, which requires a special approach to this category of patients. Comorbid course of these pathologies has a negative effect on the severity of the disease, worsens the prognosis of the course, reduces the course of the course, reduces the course of the disease of life such patients. Of particular relevance is the treatment of patients, the modernization of pulmonary rehabilitation (LR) programs, which include physical training of patients. Development and integration of a comprehensive innovative system of methods for the rehabilitation of comorbid patients suffering from COPD and metabolic syndrome, including a theoretical training program, general physical training and the use of a computer system for training the respiratory muscles. A total of 184 patients diagnosed with high-severity HOBL and metabolic syndrome were selected for research. Inthe first group, a pulmonary rehabilitation programme and standard drug therapy for COPD patients were included in thetreatment programme; The second, a control one, included patients receiving only standard drug therapy. With the help ofthe computer program "(Pulmosys)" a survey of the severity of the course of COPD was carried out. During research, the first group of comorbid patients whose treatment program included both LR and standarddrug therapy showed statistically significant positive dynamics, compared with the control group. Complex therapy in patients with COPD and the presence of metabolic syndrome leads to a decrease in the numberof exacerbations and hospitalizations for the underlying disease, the severity of clinical symptoms, and a decrease in thesystemic inflammatory response. The inclusion of the pulmonary rehabilitation program in the management scheme of patients with comorbidcourse of COPD and metabolic syndrome, the optimization of therapeutic and preventive measures statisticallysignificantly improves the quality of life of such patients and the prognosis of the course of the disease.

chronic obstructive pulmonary diseasepulmonary rehabilitationtreatment and prophylactic program

Relevance: The course of chronic obstructive pulmonary disease (COPD) is often caused by metabolic syndrome, which requires a special approach to this category of patients[1]. The comorbid course of these pathologies has a negative effect on the severity of the disease, worsens the prognosis of the course, reduces the life expectancy of such patients[2, 3]. These factors significantly increase the number of hospitalizations, which increases the cost of treatment, cause an increase in disability and mortality [4]. Of particular relevance is the improvement of clinical effective therapy of pregnant patients, the modernization of pulmonary rehabilitation (LR) programs, which include physical training of the respiratory muscles. Objective: Development and integration of a comprehensive innovative system of methods for the rehabilitationof comorbid patients suffering from COPD and metabolic syndrome, including a theoretical training program, generalphysical training and the use of a computer system for training the respiratory muscles. Materials and methods: A total of 184 patients diagnosed with COPD and metabolic syndrome (106 men, 78women; mean age 48.36 0.32 years) were selected for the research. The first group (104 people) included patientsdiagnosed with high-severity HOBL and metabolic syndrome, whose treatment program included a pulmonaryrehabilitation program and standard drug therapy for COPD patients; The second group (80 hours), which includedpatients receiving only standard drug therapy, was a control group. With the help of the computer program "(Pulmosys)" a survey of the severity of the course of COPD was carried out. This program included the following indicators: the numberof exacerbations of the disease during the year, the number of hospitalizations during the year. Results: During the research, the first group of comorbid patients, whose treatment program included both LR and standard drug therapy, showed a statistically significant positive trend compared to the control group. In the first group, exercise tolerance (6MWT) increased statistically significantly, clinical and laboratory-instrumental parameters improved, the severity of clinical symptoms, the degree of effect of shortness of breath on health, as well as the number ofexacerbations and hospitalizations during the year of observation. Discussion: Conducting complex therapy in patients with COPD and the presence of metabolic syndrome leads to a decrease in the number of exacerbations and hospitalizations for the underlying disease, the severity of their clinical symptoms, a decrease in the systemic inflammatory response. During the research, a positive effect on the underlying disease was noted. psycho-emotional status, improvement of the quality of life of this category of patients and subjective positive emotional impact on the perception of the disease. Conclusion: The inclusion of the pulmonary rehabilitation program in the management scheme of patients with a comorbid course of COPD and metabolic syndrome, the optimization of therapeutic and preventive measures statistically significantly improves the quality of life of such patients and the prognosis of the course of the disease.

Clinical efficacy of roflumilast and pulmonary rehabilitation in patients with chronic obstructive pulmonary disease and type 2 diabetes mellitus / Budnevsky A.V., Ovsyannikov E.S., Pertsev A.V., Polyakova N.V. / Practical pulmonology. 2017. № 2. S. 29-36. (In RUS)

Vaccination in combination with a course of pulmonary rehabilitation in patients with chronic obstructive pulmonary disease / Pertsev A.V., Budnevsky A.V., Ovsyannikov E.S., Pertseva M.V. / Preventive medicine. 2018. T. 21. № 2-2. S. 18-19. (In RUS)

Clinical efficacy of the use of roflumilast in patients with chronic obstructive pulmonary disease and concomitant coronary heart disease / Pertsev A.V., Budnevsky A.V., Ovsyannikov E.S., Pertseva M.V. / In the collection: Modern strategies and technologies for the prevention, diagnosis, treatment and rehabilitation of patients of different ages suffering from chronic non-infectious diseases. Materials of the International Scientific and Practical Conference. Edited by N.K. Gorshunova. 2018. S. 215-225. (In RUS)

Modern approaches to improving the quality of life of patients with chronic obstructive pulmonary disease / Pertsev A.V., Budnevsky A.V., Ovsyannikov E.S., Pertseva M.V. / In the collection: Modern strategies and technologies for the prevention, diagnosis, treatment and rehabilitation of patients of different ages suffering from chronic non-communicable diseases. Materials of the International Scientific and Practical Conference. Edited by N.K. Gorshunova. 2018. S. 75-82. (In RUS)