Молодежный инновационный вестникМолодежный инновационный вестник2415-7805Федеральное государственное бюджетное образовательное учреждение высшего образования "Воронежский государственный медицинский университет имени Н.Н. Бурденко" Министерства здравоохранения Российской Федерации8216UnclassifiedMENTAL DISORDERS IN IRON DEFICIENCY ANEMIAMorozovaAlina L.alinka090803@mail.ruhttps://orcid.org/0000-0001-6107-7405ErkenovaDiana R.erkenova.d@yandex.ruhttps://orcid.org/0009-0008-8159-5347Saratov State Medical University named after V. I. Razumovsky2004202312S24054073101202311042023Copyright © 2023, Morozova A.L., Erkenova D.R.2023<p><strong>The aim:</strong> To examine the effects of iron deficiency on mental processes.<strong>Relevance:</strong> Iron deficiency is the most common nutritional disorder worldwide and accounts for approximately half of anemia, making iron deficiency anemia a public health problem. The etiology of this disease varies and is explained by several risk factors that decrease iron intake and absorption or increase demand and loss, with multiple etiologies often coexisting in an individual patient. Although symptoms may be nonspecific, there is emerging evidence of the deleterious impact of iron deficiency anemia on clinical outcomes in a wide range of conditions, including psychiatric disorders and cognitive impairment. Increased awareness of the consequences and prevalence of iron deficiency anemia may facilitate earlier detection and treatment. <strong>Materials and methods:</strong> during the work we used data of scientific materials on the topic of iron deficiency anemia of leading domestic and foreign specialists in this field of psychiatry, as well as Russian- and English-language articles available in the databases: ELibrary.ru, Scopus, PubMed, Google Scholar, Europe PMC. The materials were searched using the keywords: GAD, iron deficiency anemia, iron metabolism. Inclusion criteria: full-text articles in Russian and English; original studies; clinical observations; monographs; guidelines. A total of 9 publications were found. <strong>Results:</strong> a literature review was conducted. <strong>Conclusions:</strong> iron plays a significant role in the functioning of neurotransmitter systems and basal ganglia; deficiency of this element is registered in a number of psychiatric and neurological disorders.</p>Iron deficiency anemiamental disordersdepressioncognitive functionжелезодефицитная анемияпсихические расстройствадепрессиякогнитивные функции[Elstrott B, Khan L, Olson S, Raghunathan V, DeLoughery T, Shatzel JJ. The role of iron repletion in adult iron deficiency anemia and other diseases. Eur J Haematol. 2020;104(3):153-161. doi:10.1111/ejh.13345][Naigamwalla DZ, Webb JA, Giger U. Iron deficiency anemia. CanVet J. 2012;53(3):250-256.][Bouri S, Martin J. Investigation of iron deficiency anaemia . Clin Med (Lond). 2018;18(3):242-244. doi:10.7861/clinmedicine.18-3-242][Chifman J, Laubenbacher R, Torti SV. A systems biology approach to iron metabolism. AdvExpMedBiol. 2014;844:201-225. doi:10.1007/978-1-4939-2095-2_10][Chen MH, Su TP, Chen YS, et al. Association between psychiatric disorders and iron deficiency anemia among children and adolescents: a nationwide population-based study. BMC Psychiatry. 2013;13:161. Published 2013 Jun 4. doi:10.1186/1471-244X-13-161][Kim J, Wessling-Resnick M. Iron and mechanisms of emotional behavior. J NutrBiochem. 2014;25(11):1101-1107. doi:10.1016/j.jnutbio.2014.07.003][Shah HE, Bhawnani N, Ethirajulu A, et al. Iron Deficiency-Induced Changes in the Hippocampus, Corpus Striatum, and Monoamines Levels That Lead to Anxiety, Depression, Sleep Disorders, and Psychotic Disorders. Cureus. 2021;13(9):e18138. Published 2021 Sep 20. doi:10.7759/cureus.18138][Изменения памяти и комплаентности у пациентов с анемией / Л.М. Салимова, А.Ф. Окурлу, Р.Ф. Хамитов [и др.] // Вестник современной клинической медицины. – 2019. – Т. 12, вып. 5. – С.55–58. DOI: 10.20969/ VSKM.2019.12(5).55-58.][Kim SW, Stewart R, Park WY, et al. Latent Iron Deficiency as a Marker of Negative Symptoms in Patients with First-Episode Schizophrenia Spectrum Disorder. Nutrients. 2018;10(11):1707. Published 2018 Nov 8. doi:10.3390/nu10111707]