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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" article-type="research-article" dtd-version="1.1d1" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher">Молодежный инновационный вестник</journal-id><journal-title-group><journal-title>Молодежный инновационный вестник</journal-title></journal-title-group><issn publication-format="print">2415-7805</issn><publisher><publisher-name>Федеральное государственное бюджетное образовательное учреждение высшего образования "Воронежский государственный медицинский университет имени Н.Н. Бурденко" Министерства здравоохранения Российской Федерации</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">8178</article-id><article-categories><subj-group subj-group-type="heading"><subject>Unclassified</subject></subj-group></article-categories><title-group><article-title>DEPENDENCE OF THE SEVERITY OF CORONARY ATHEROSCLEROSIS ON COPD PHENOTYPE</article-title></title-group><contrib-group><contrib contrib-type="author"><name name-style="western"><surname>Axelrod</surname><given-names>Mariya Mikhailovna</given-names></name><bio>&lt;div id="tw-target-text-container" class="tw-ta-container F0azHf tw-nfl" tabindex="0"&gt;
&lt;pre id="tw-target-text" class="tw-data-text tw-text-large tw-ta" dir="ltr" data-placeholder="Перевод"&gt;&lt;span class="Y2IQFc" lang="en"&gt;Postgraduate Student of the Department of Polyclinic Therapy&lt;/span&gt;&lt;/pre&gt;
&lt;/div&gt;</bio><email>axelrodmasha@mail.ru</email><uri content-type="orcid">https://orcid.org/0000-0001-5068-1316</uri><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff id="aff-1">Voronezh State Medical University named after V.I. N.N. Burdenko</aff><pub-date date-type="epub" iso-8601-date="2023-04-20" publication-format="electronic"><day>20</day><month>04</month><year>2023</year></pub-date><volume>12</volume><issue>S2</issue><fpage>94</fpage><lpage>96</lpage><history><pub-date date-type="received" iso-8601-date="2023-01-30"><day>30</day><month>01</month><year>2023</year></pub-date><pub-date date-type="accepted" iso-8601-date="2023-03-13"><day>13</day><month>03</month><year>2023</year></pub-date></history><permissions><copyright-statement>Copyright © 2023, Axelrod M.M.</copyright-statement><copyright-year>2023</copyright-year></permissions><abstract>&lt;p&gt;&lt;span class="HwtZe" lang="en"&gt;&lt;strong&gt;&lt;span class="jCAhz ChMk0b"&gt;&lt;span class="ryNqvb"&gt;Relevance.&lt;/span&gt;&lt;/span&gt; &lt;/strong&gt;&lt;span class="jCAhz ChMk0b"&gt;&lt;span class="ryNqvb"&gt;Despite the fact that coronary heart disease, as a separate disease, is quite well studied, there are many less developed problems associated with the combination of coronary artery disease and other nosologies.&lt;/span&gt;&lt;/span&gt; &lt;span class="jCAhz ChMk0b"&gt;&lt;span class="ryNqvb"&gt;According to many authors, it has been established that patients with COPD are much more likely to die from cardiovascular pathology than from COPD itself.&lt;/span&gt;&lt;/span&gt; &lt;span class="jCAhz ChMk0b"&gt;&lt;span class="ryNqvb"&gt;It was determined that people with COPD have the most severe atherosclerotic lesions of the coronary arteries in comparison with the group without COPD.&lt;/span&gt;&lt;/span&gt; &lt;span class="jCAhz ChMk0b"&gt;&lt;span class="ryNqvb"&gt;There are various classifications of COPD, but none of them reflects the relationship between the severity of coronary atherosclerosis and the COPD phenotype.&lt;/span&gt;&lt;/span&gt; &lt;span class="jCAhz ChMk0b"&gt;&lt;span class="ryNqvb"&gt;In this regard, the evaluation of coronary lesions in patients with various COPD phenotypes is of increased interest. &lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/p&gt;&#13;
&lt;p&gt;&lt;span class="HwtZe" lang="en"&gt;&lt;strong&gt;&lt;span class="jCAhz ChMk0b"&gt;&lt;span class="ryNqvb"&gt;Purpose.&lt;/span&gt;&lt;/span&gt; &lt;/strong&gt;&lt;span class="jCAhz ChMk0b"&gt;&lt;span class="ryNqvb"&gt;Determination of the COPD phenotype most susceptible to severe coronary atherosclerosis. &lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/p&gt;&#13;
&lt;p&gt;&lt;span class="HwtZe" lang="en"&gt;&lt;strong&gt;&lt;span class="jCAhz ChMk0b"&gt;&lt;span class="ryNqvb"&gt;Materials and methods.&lt;/span&gt;&lt;/span&gt;&lt;/strong&gt; &lt;span class="jCAhz ChMk0b"&gt;&lt;span class="ryNqvb"&gt;The study involved 74 people with a diagnosis of chronic obstructive pulmonary disease, which was confirmed and verified by clinical and functional methods and standardized criteria.&lt;/span&gt;&lt;/span&gt; &lt;span class="jCAhz ChMk0b"&gt;&lt;span class="ryNqvb"&gt;All patients were confirmed to have coronary atherosclerosis by coronary angiography.&lt;/span&gt;&lt;/span&gt; &lt;span class="jCAhz ChMk0b"&gt;&lt;span class="ryNqvb"&gt;The severity of coronary atherosclerosis was assessed by the Gensini index. &lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/p&gt;&#13;
&lt;p&gt;&lt;span class="HwtZe" lang="en"&gt;&lt;strong&gt;&lt;span class="jCAhz ChMk0b"&gt;&lt;span class="ryNqvb"&gt;Results.&lt;/span&gt;&lt;/span&gt;&lt;/strong&gt; &lt;span class="jCAhz ChMk0b"&gt;&lt;span class="ryNqvb"&gt;The COPD phenotype most susceptible to coronary atherosclerosis was identified according to coronary angiography data. &lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/p&gt;&#13;
&lt;p&gt;&lt;span class="HwtZe" lang="en"&gt;&lt;strong&gt;&lt;span class="jCAhz ChMk0b"&gt;&lt;span class="ryNqvb"&gt;Conclusion.&lt;/span&gt;&lt;/span&gt;&lt;/strong&gt; &lt;span class="jCAhz ChMk0b"&gt;&lt;span class="ryNqvb"&gt;According to the study, the risk of developing coronary atherosclerosis in this COPD phenotype is the highest, which can be used as a prognostic indicator at the outpatient stage.&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/p&gt;</abstract><kwd-group xml:lang="en"><kwd>chronic obstructive pulmonary disease</kwd><kwd>coronary atherosclerosis</kwd><kwd>Gensini index</kwd><kwd>COPD phenotypes</kwd><kwd>coronary heart disease</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>хроническая обструктивная болезнь легких</kwd><kwd>коронарный атеросклероз</kwd><kwd>индекс Gensini</kwd><kwd>фенотипы ХОБЛ</kwd><kwd>ишемическая болезнь сердца</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Global status report on noncommunicable diseases 2014. WHO Library Cataloguing-in-Publication Data. Geneva, 2014. – 398p.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>ВНОК. Кардиоваскулярная профилактика. Национальные рекомендации. Кардиоваскулярная терапия и профилактика. 2011;10 (6 Прил 2):1–64.</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Оганов Р. Г. Сердечно-сосудистые заболевания в начале XXI века: медицинские, социальные, демографические аспекты и пути профилактики. Медицина труда, восстановительная и профилактическая медицина. 2010;11:257–64.</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>Петрухин И. С., Лунина Е. Ю. Актуальные проблемы профилак- тики сердечно-сосудистых заболеваний в России. 2012. Верхне- волжский медицинский журнал. 2012;10 (1):1–6.</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>Celli BR, Barnes PJ. Exacerbations of chronic obstructive pulmo- nary disease. Eur Respir J. 2007 Jun;29 (6):1224–38.</mixed-citation></ref><ref id="B6"><label>6.</label><mixed-citation>Mathers CD, Loncar D. Projections of global mortality and burden of disease from 2002 to 2030. PLoS Med. 2006 Nov;3 (11):e442.</mixed-citation></ref><ref id="B7"><label>7.</label><mixed-citation>Halbert RJ, Natoli JL, Gano A, Badamgarav E, Buist AS, Mannino DM. Global burden of COPD: systematic review and meta-analysis. Eur Respir J. 2006 Sep;28 (3):523–32.</mixed-citation></ref><ref id="B8"><label>8.</label><mixed-citation>Pauwels RA, Buist AS, Calverley PM, Jenkins CR, Hurd SS. Global strategy for the diagnosis, management and prevention of chronic obstructive pulmonary disease. NHLBI/WHO Global Initiative for Chronic Obstructive Lung Disease (GOLD) Workshop sum- mary. Am J Respir Crit Care Med. 2001 Apr;163 (5):1256–76.</mixed-citation></ref><ref id="B9"><label>9.</label><mixed-citation>Rycroft CE, Heyes A, Lanza L, Becker K. Epidemiology of chronic obstructive pulmonary disease: a literature review. Int J Chron Obstruct Pulmon Dis. 2012;7:457–94.</mixed-citation></ref><ref id="B10"><label>10.</label><mixed-citation>Чучалин А.Г., Авдеев С.Н., Айсанов З.Р. и др. Российское респираторное общество. Федеральные клинические рекомендации по диагностике и лечению хронической обструктивной болезни легких. Пульмонология. 2014;3:15–54</mixed-citation></ref></ref-list></back></article>
