Молодежный инновационный вестникМолодежный инновационный вестник2415-7805Федеральное государственное бюджетное образовательное учреждение высшего образования "Воронежский государственный медицинский университет имени Н.Н. Бурденко" Министерства здравоохранения Российской Федерации6279Features of the course of thyroid diseases in childrenLebedevaElizaveta S.Lizavetalebedeva@yandex.ruhttps://orcid.org/0000-0002-7456-9756KitsenkoAlisa I.alisa_lavine@mail.ruhttps://orcid.org/0000-0001-7282-8390Voronezh Medical University N. N. Burdenko1512202092S2412430912202011122020Copyright © 2022, Lebedeva E.S., Kitsenko A.I.2022<p>Thyroid diseases are a serious problem in modern healthcare. The study of this pathology, the peculiarities of its clinical picture and variants of the course in children will improve the timely diagnosis of diseases and determine the prognosis.</p> <p>Objective: to study the features of the course of thyroid diseases in children.</p> <p>Methods: the study included analysis of medical records from 2017 to 2019, 91 children aged 1 to 18 years with thyroid diseases. In order to assess the characteristics of the course of the disease, a statistical analysis of the data obtained was carried out.</p> <p>Results: 91 children aged from 1 to 18 years old were selected to participate in the study, among them 49 were girls and 42 were boys, 72 people were residents of the city and 19 people were residents of the region. The subjects were divided into three groups. Group I included 23 people with diffuse non-toxic goiter. Group II consisted of 10 people with diffuse toxic goiter. Group III included 22 people with autoimmune thyroiditis. During the work, it was revealed that the hypofunction of the thyroid gland was more often accompanied by obesity (r = 0.24, p 0.05), and children more often complained of increased fatigue (r = 0.651, p 0.05), headaches ( r = 0.267, p 0.05). Hypertriglyceridemia was more common in hypothyroidism (r = 0.243, p 0.05). With manifest thyrotoxicosis, an increase in the level of high-density lipoproteins was more often observed (r = 0.28, p 0.05). In patients with protein-energy deficiency, there was a decrease in the level of high-density lipoproteins (r = 0.26, p 0.05). Rhythm disturbances were more often observed in children with deviations in physical development (with protein-energy deficiency r = 0.31, p 0.05; with obesity, r = 0.28, p 0.05). There was a direct correlation between the level of cholesterol and the degree of obesity (r = 0.21, p 0.05).</p> <p>Conclusion: The results of this study revealed the lack of specificity of the clinical picture of the manifestation of thyroid pathology. Thyroid function in diffuse non-toxic goiter and autoimmune thyroiditis is more often characterized by euthyroidism. The hypofunction of the thyroid gland more often contributed to the development of obesity and dyslipidemia in patients. With overt thyrotoxicosis, an increase in HDL levels was more often observed. In patients with protein-energy deficiency, there was a decrease in HDL levels. Rhythm disturbances were more often observed in children with disabilities in physical development.</p>diseases of the thyroid glandchildrenlipid profileзаболевания щитовидной железыдетилипидограмма1.1. Прусова А.А. Возможные вторичные и сопутствующие заболевания различных патологий щитовидной железы / А.А. Прусова, А.А. Эйрих // Научное обозрение. Медицинские науки. – 2018. – №1. – С. 21 – 24.2.2. Заболевания щитовидной железы и риск возникновения нетиреоидной патологии / Р.И. Глушаков, Е.В. Козырко. И.В. Соболев [и др.] // Казанский медицинский журнал. – 2017. – Т. 98, №1. – С. 77 – 84.