Молодежный инновационный вестникМолодежный инновационный вестник2415-7805Федеральное государственное бюджетное образовательное учреждение высшего образования "Воронежский государственный медицинский университет имени Н.Н. Бурденко" Министерства здравоохранения Российской Федерации11529Conference ProceedingsFeatures of the course of pertussis complicated by pneumonia in children under one year of agePoliakovaViktoriia Dmitrievnalyalinavika1201@gmail.comhttps://orcid.org/0009-0001-3465-7735YatsenkoAleksandra Sergeevna89513176447www@gmail.comhttps://orcid.org/0009-0005-7169-1077SevostianovaKseniya Maksimovnacurtyzhiv45@gmail.comhttps://orcid.org/0009-0002-8822-6049MakarovaAlla Vyacheslavovna1alla2011@mail.ruhttps://orcid.org/0000-0001-6901-314XBurdenko Voronezh State Medical University0110202615S11611631603202611042026Copyright © 2026, Poliakova V.D., Yatsenko A.S., Sevostianova K.M., Makarova A.V.2026<p style="text-align: justify;">Despite universal vaccination, pertussis remains a significant issue in pediatrics, with an increase in incidence recorded in Russia in 2024. Infants under one year of age, especially unvaccinated children under 3 months, are the most vulnerable group, often experiencing atypical disease progression and severe complications like pneumonia. Objective. identify the specific features of pertussis complicated by pneumonia in infants.<br />Materials and methods.A retrospective analysis was conducted on 24 medical records of patients aged 1 month to 1 year with laboratory-confirmed pertussis and pneumonia, treated in a hospital from 2016 to 2025. Results.The average patient age was 5 months, with 42% being under 3 months old. In 100% of cases, pertussis was complicated by pneumonia. Mixed infections (viral, bacterial, CMV) were detected in 58% of children. Respiratory failure in 79% of cases was caused by broncho-obstructive syndrome. A characteristic laboratory finding was lymphocytic leukocytosis, with hyperleukocytosis (5010⁹/L) in 18% of young infants serving as a poor prognostic marker.<br />Conclusion. Pneumonia is the dominant complication of pertussis in infants. Children in the first three months of life are at the highest risk of severe illness. A white blood cell count exceeding 5010⁹/L is a criterion for extremely severe cases and requires careful monitoring.<em><br /><br /></em></p>pertussisinfantspneumoniabroncho-obstructive syndromehyperleukocytosiscytomegalovirus infectionкоклюшдети до годапневмониябронхообструктивный синдромгиперлейкоцитозцитомегаловирусная инфекция 1.Xu, M Lei, Y & Tan, K & Deng, J. (2018). Clinical analysis of 309 hospitalized children with pertussis-associated pneumonia. Zhonghua er ke za zhi. Chinese journal of pediatrics. 56. 686-690. 10.3760/cma.j.issn.0578-1310.2018.09.010.2.Abu-Raya, Bahaa & Goldfarb, David & Smieja, Marek & Luinstra, Kathy & Richard-Greenblatt, Melissa & Steenhoff, Andrew & Feemster, Kristen & Arscott-Mills, Tonya & Cunningham, Coleen & Shah, Samir & Patel, Mohamed & Kelly, Matthew & Sadarangani, Manish. (2019). The prevalence and clinical characteristics of pertussis-associated pneumonia among infants in Botswana. BMC Pediatrics. 19. 10.1186/s12887-019-1820-0.3.Васюнин Александр Васильевич, Краснова Елена Игоревна, Карпович Глеб Сергеевич Возможные факторы риска и предикторы развития пневмонии при коклюшной инфекции // Journal of Siberian Medical Sciences. 2019. №4./С.109-1194.Кокорева С. П., Илунина Л. М., Макарова А. В., Течение коклюша в современных условиях. Лечение и профилактика 2018; 8 (4): 31-35