Молодежный инновационный вестникМолодежный инновационный вестник2415-7805Федеральное государственное бюджетное образовательное учреждение высшего образования "Воронежский государственный медицинский университет имени Н.Н. Бурденко" Министерства здравоохранения Российской Федерации11365Conference ProceedingsRetrospective analysis of the drug sensitization profile of patients in the city of StavropolShiyanovDmitry Sergeevich<p>Assistant at the Department of Clinical Pharmacology with a course in continuing education</p>dr.shiyanov@yandex.ruhttps://orcid.org/0009-0001-7582-6005BaturinVladimir Alexandrovich<p>DMSс, Professor, Head of the Department of Clinical Pharmacology with a course in continuing education</p>prof.baturin@gmail.comhttps://orcid.org/0000-0002-6892-3552Stavropol State Medical University0110202615S12232242802202605042026Copyright © 2026, Shiyanov D.S., Baturin V.A.2026<p style="text-align: justify;">Due to the growth of the pharmaceutical market and the expansion of the range of medicinal products, the number of drug-induced side effects is inevitably increasing. Among these, allergic reactions stand out as they are unpredictable, dose-independent, and unrelated to the main pharmacological action of the drug. Objective. To identify the groups of drugs and substances to which sensitization was most frequently observed, based on the results of laboratory allergy tests conducted at the "Center for Clinical Pharmacology and Pharmacotherapy" in Stavropol for the year 2017. Materials and Methods. A retrospective analysis was performed on 2570 reports of allergy tests for medicinal products and dietary supplements, conducted at the "Center for Clinical Pharmacology and Pharmacotherapy" in Stavropol during 2017. To detect the immunological mechanisms of hypersensitivity to drugs, laboratory diagnostic methods were used - the myeloperoxidase test (MPT) and the determination of circulating immune complexes (CIC). Results. Immunological mechanisms of hypersensitivity were identified for 836 items - of these, 165 (19.7%) were local anesthetics, 154 (18.4%) were antibiotics, and 56 (6.7%) were NSAIDs. Conclusion. According to the results of laboratory allergy tests, sensitization to local anesthetics, antibiotics, and non-steroidal anti-inflammatory drugs was most frequently observed.</p>drug allergyhypersensitivitysensitizationлекарственная аллергиягиперчувствительностьсенсибилизация1.Butranova O, Zyryanov S, Gorbacheva A, Asetskaya I, Polivanov V. Drug-Induced Anaphylaxis: National Database Analysis. Pharmaceuticals. 2024; 17(1):90. https://doi.org/10.3390/ph170100902.Doña I, Torres MJ, Celik G, Phillips E, Tanno LK, Castells M. Changing patterns in the epidemiology of drug allergy. Allergy. 2024;79(3):613-628. https://doi.org/10.1111/all.159703.Шнайдер, К. О. Оценка осведомленности практикующих врачей о порядке осуществления фармаконадзора / К. О. Шнайдер, М. Л. Максимов // Вестник Биомедицина и социология. – 2025. – Т. 10, № 1. – С. 39-45. – DOI 10.26787/nydha-2618-8783-2025-10-1-39-45. – EDN FSTKBP.4.Юркевич А.В., Ушницкий И.Д., & Казакова Е.В. (2019). Эпидемиология аллергических реакций в поликлинической стоматологии в возрастно-половом аспекте. Дальневосточный медицинский журнал, (1), 38-40.