Молодежный инновационный вестникМолодежный инновационный вестник2415-7805Федеральное государственное бюджетное образовательное учреждение высшего образования "Воронежский государственный медицинский университет имени Н.Н. Бурденко" Министерства здравоохранения Российской Федерации11301Conference ProceedingsOrganotopographic study of peripheral vascular and cardiac thrombosisDenisovaDarya Evgenievna<p>student</p>puzar.mila@yandex.ruhttps://orcid.org/0009-0008-3197-3426AgababyanMilena Armanovna<p>student</p>puzar.mila@yandex.ruhttps://orcid.org/0009-0008-4803-7706MnikhovichMaxim Valerievich<p>Head of the Department of Normal Anatomy, Leading Researcher</p>mnichmaxim@yandex.ruhttps://orcid.org/0000-0001-7147-7912ShiripenkoIvan Alexandrovich<div class="src ltr">Junior researcher; assistant of the Department of normal anatomy</div>hikkiwahikki@gmail.comhttps://orcid.org/0000-0002-5947-1523Petrovsky Medical University, Petrovsky Russian Research Center of SurgeryPetrovsky Medical University, Petrovsky Russian Research Center of Surgery, Avtsyn Research Institute of Human Morphology, Petrovsky Russian Research Center of SurgeryAvtsyn Research Institute of Human Morphology of Federal State Budgetary Scientific InstitutionPetrovsky Medical University "Petrovsky National Research Center of Surgery"0110202615S1572502202605042026Copyright © 2026, Denisova D.E., Agababyan M.A., Mnikhovich M.V., Shiripenko I.A.2026<p style="text-align: justify;"><span style="font-weight: 400;">The problem of peripheral vascular and cardiac thrombosis has a great importance in clinical medicine because it underlies the development and progression of a significant part of cardiovascular diseases. This paper describes the main classical and modern methods of investigation and visualization of thrombotic occlusion and ischemic lesions in the area of interest. As an alternative to the existing methods, the use of cuts of frozen amputation material according to the author's modification of the method of N.I. Pirogov is proposed. It is proposed to use this method for the morphological assessment of vascular thrombosis of the extremities, which ensures the preservation of the natural topography of tissues and thrombotic masses with the possibility of subsequent sampling of the vessel with a thrombus and perivascular tissue. The collected material was microscopically studied in hematoxylin and eosin stains, as well as by Masson. Together with the method of topographic examination of peripheral vessels, an original method of opening the heart, pulmonary trunk and pulmonary arteries is proposed, which minimizes the risk of dislocation of thromboemboli and increases the reliability of the diagnosis of pulmonary embolism. Organotopographic identification of areas of thrombotic vascular occlusion, including extensive total thrombosis of a vessel or vascular system, has a fundamental importance in the context of assessing the prevalence of thrombosis and thrombogenic complications.</span></p>thrombosistopographythrombogenic complicationsresearch methodsautopsy methodтромбозтопографиятромбогенные осложненияметоды исследованияметод вскрытия1.Базарова А., Вердиева С., Эргашева З., Ахунова А. Тромбоэмболия легочной артерии (ТЭЛА): современные представления и лечение. Сборник статей XI Международной научно-практической конференции: в 3 ч. Пенза, 2024 г. - С. 155-156.2.Wolberg AS, Rosendaal FR, Weitz JI, Jaffer IH, Agnelli G, Baglin T, и др. Venous thrombosis. Nat Rev Dis Primers. 7 май 2015 г.;1:15006. doi:10.1038/nrdp.2015.6 PubMed PMID: 27189130.3.Maffeis V, Nicolè L, Rago C, Fassina A. Histological criteria for age determination of fatal venous thromboembolism. Int J Legal Med. май 2018 г.;132(3):775–80. doi:10.1007/s00414-017-1705-4 PubMed PMID: 29052040.4.Yoshimiya M, Ueda T, Takeuchi I, Ueda A, Kakimoto Y. Imaging changes of pulmonary thromboembolism on postmortem computed tomography. Forensic Sci Med Pathol. 5 ноябрь 2025 г. doi:10.1007/s12024-025-01108-25.Elhammady G, Schubeck AT, El-Najjar V, Robinson MJ. Postmortem Demonstration of the Source of Pulmonary Thromboembolism: The Importance of the Autopsy. Case Rep Vasc Med. 2011 г.;2011:108215. doi:10.1155/2011/108215 PubMed PMID: 22937459; PubMed Central PMCID: PMC3420703.6.Н.И. Пирогов и его «Ледяная анатомия»: современная модификация метода распилов замороженных органов и новейшие способы их сохранения / М. В. Мнихович, И. А. Ширипенко, М. В. Лозина [и др.] // Оперативная хирургия и клиническая анатомия (Пироговский научный журнал). – 2024. – Т. 8, № 1. – С. 59-68.