Молодежный инновационный вестникМолодежный инновационный вестник2415-7805Федеральное государственное бюджетное образовательное учреждение высшего образования "Воронежский государственный медицинский университет имени Н.Н. Бурденко" Министерства здравоохранения Российской Федерации10912UnclassifiedEvaluation of the relationship between arterial stiffness and body composition parameters in young personsZhilinaAnastasiazhilina_anastasia01@mail.ruhttps://orcid.org/0009-0004-7784-6204ValeevaElenavevaleeva@ya.ruhttps://orcid.org/0000-0001-7080-3878YegorovaEmiliajastspring@yandex.ruhttps://orcid.org/0000-0002-6210-4660AkhmetovIldusgenoterra@mail.ruhttps://orcid.org/0000-0002-6335-40200411202514248501604202505082025Copyright © 2025, Zhilina A., Valeeva E., Yegorova E., Akhmetov I.2025<p>Аннотация на английском:</p> <p>The prevalence of obesity in young people has been increasing in recent decades, which has led to an elevated cardiovascular risk. However, it is important to note that young people often exhibit what is termed "metabolically healthy obesity", in which excess weight is not accompanied by typical metabolic abnormalities, making early diagnosis difficult.</p> <p>Arterial stiffness, as measured by the CAVI (Cardio-Ankle Vascular Index), has been identified as an independent marker of vascular ageing, with a reduced reliance on blood pressure compared to other methodologies. The present study involved 51 students (mean age: 21.7 3.0 years). Their body composition was assessed by means of the bioelectrical impedance method (Tanita MC-780 MAN), and arterial stiffness was measured by volumetric sphygmography (Vasera VS-2000) and expressed as CAVI (Cardio-Ankle Vascular Index).</p> <p>The results revealed a negative association of CAVI with BMI (P=0.003), fat (P=0.009), and skeletal muscle mass (P=0.022). These findings contradict traditional views of the negative effects of obesity on the vascular system and are consistent with the concept of the "obesity paradox". Potential explanations for these findings include compensatory mechanisms in young adults, the influence of physical activity, and the protective role of muscle mass.</p> <p>The findings emphasise the limitations of BMI as a marker of cardiovascular risk in young age and underscore the necessity of employing integrated measures such as CAVI for early diagnosis.</p>1.1. Ng, M. Global, regional, and national prevalence of overweight and obesity in children and adults during 1980-2013: a systematic analysis for the Global Burden of Disease Study 2013 / M. Ng, T. Fleming, M. Robinson et al. // Lancet (London, England). - 2014. - Vol. 384, № 9945. - P. 766-781.2.2. Blüher, M. Metabolically Healthy Obesity / M. Blüher // Endocrine reviews. - 2020. - Vol. 41, № 3. - Art. bnaa004.3.3. Bäck, M. Cardio-ankle vascular index for predicting cardiovascular morbimortality and determinants for its progression in the prospective advanced approach to arterial stiffness (TRIPLE-A-Stiffness) study / M. Bäck, J. Topouchian, C. Labat et al. // EBioMedicine. - 2024. - Vol. 103. - Art. 105107.4.4. Saiki, A. New Horizons of Arterial Stiffness Developed Using Cardio-Ankle Vascular Index (CAVI) / A. Saiki, M. Ohira, T. Yamaguchi et al. // Journal of atherosclerosis and thrombosis. - 2020. - Vol. 27, № 8. - P. 732-748.5.5. Евсевьева, М.Е. Молодёжный "парадокс ожирения" с позиций сосудистой жёсткости, уровня артериального давления и метаболического статуса / М.Е. Евсевьева, О.В. Сергеева, А.В. Русиди и др. // Российский кардиологический журнал. - 2024. - Т. 29, № 5. - С. 5739. EDN: BIOOTS