Молодежный инновационный вестник

2415-7805

Федеральное государственное бюджетное образовательное учреждение высшего образования "Воронежский государственный медицинский университет имени Н.Н. Бурденко" Министерства здравоохранения Российской Федерации

10902

Unclassified

Contribution of tumor tissue mediators to the choice of treatment tactics for patients with renal cell carcinoma

Gaivoronskaya

Anna

vip.anna228@mail.ruhttps://orcid.org/0009-0005-6533-0806Vasilev

Yuriy

PopyhovaEB@mail.ruhttps://orcid.org/0009-0006-6946-5027Subbotina

Elena

popyhovaeb@mail.ruhttps://orcid.org/0009-0004-3355-4146Zakharova

Nataliya B.

<pre id="tw-target-text" class="tw-data-text tw-text-large tw-ta" dir="ltr" data-placeholder="Перевод" data-ved="2ahUKEwji6u3evI2PAxVlsVYBHaZkFsQQ3ewLegQICRAW" aria-label="Переведенный текст: Doctor of Medical Sciences, Professor of the Department of Biochemistry and Clinical Laboratory Diagnostics">Doctor of Medical Sciences, Professor of the Department of Biochemistry and Clinical Laboratory Diagnostics</pre>lipidgormon@mail.ruhttps://orcid.org/0000-0001-9410-2240Popyhova

Era B.

<pre id="tw-target-text" class="tw-data-text tw-text-large tw-ta" dir="ltr" data-placeholder="Перевод" data-ved="2ahUKEwji6u3evI2PAxVlsVYBHaZkFsQQ3ewLegQICRAW" aria-label="Переведенный текст: PhD, Associate Professor, Department of Biochemistry and Clinical Laboratory Diagnostics">PhD, Associate Professor, Department of Biochemistry and Clinical Laboratory Diagnostics</pre>popyhovaeb@mail.ruhttps://orcid.org/0000-0002-7662-4755Durnov

Denis А.

<pre id="tw-target-text" class="tw-data-text tw-text-large tw-ta" dir="ltr" data-placeholder="Перевод" data-ved="2ahUKEwji6u3evI2PAxVlsVYBHaZkFsQQ3ewLegQICRAW" aria-label="Переведенный текст: PhD, Associate Professor of the Department of Urology">PhD, Associate Professor of the Department of Urology</pre>meduniv@sgmu.ruhttps://orcid.org/0000-0002-6182-8309

V.I. Razumovsky Saratov State Medical UniversitySaratov State Medical University named after V. I. RazumovskySaratov State Medical University named after V.I. Razumovsky

04112025

1423133

15042025

16082025

2025

. In recent years, there has been an increase in the incidence of kidney cancer (КC), which is associated with an increased detection of small forms (up to 40 mm in diameter) and the number of cases of primary multiple kidney tumors. Treatment tactics for patients with primary multiple tumors have their own characteristics. Currently, there is no consensus on the optimal treatment strategy for patients with synchronous bilateral renal lesions. It has been proven that in patients with КС, the tumor parenchyma contains immune cells - this is the so-called tumor microenvironment (TME), the study of mediators of which is important for the diagnosis of local and widespread forms of КС, since it is useful in choosing treatment tactics. The study of the immune mechanisms of the body's defense and the clinical and diagnostic significance of tumor ТМЕ mediators is important for predicting the risk of tumor progression and the development of metastases in patients in the postoperative period.

kidney cancer, tumor microenvironment mediators, biomarkers.

рак почки, медиаторы микроокружения опухоли, биомаркеры.

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