Молодежный инновационный вестник

2415-7805

Федеральное государственное бюджетное образовательное учреждение высшего образования "Воронежский государственный медицинский университет имени Н.Н. Бурденко" Министерства здравоохранения Российской Федерации

10835

Conference Proceedings

Natural colonization of periodontal epithelial cells in patients with mental illnesses

Zykova

Aleksandra Sergeevna

<pre id="tw-target-text" class="tw-data-text tw-text-large tw-ta" dir="ltr" data-placeholder="Перевод" data-ved="2ahUKEwjvuJfXxMqMAxV9ExAIHWelDbsQ3ewLegQICBAV" aria-label="Переведенный текст: Assistant Professor of the Department of Therapeutic Dentistry"><span class="Y2IQFc" lang="en">Assistant of the Department of Therapeutic Dentistry</span></pre>zhukovaalica@yandex.ruhttps://orcid.org/0000-0002-2375-7634Opravin

Aleksandr Sergeevich

<pre id="tw-target-text" class="tw-data-text tw-text-large tw-ta" dir="ltr" data-placeholder="Перевод" data-ved="2ahUKEwjh87iEsNWMAxWXHBAIHR7INJkQ3ewLegQICBAV" aria-label="Переведенный текст: Doctor of Medical Sciences, Associate Professor, Head of the Department of Therapeutic Dentistry, Federal State Budgetary Educational Institution of Higher Education, Saratov State Medical University (Arkhangelsk), Ministry of Health of the Russian Federation."><span class="Y2IQFc" lang="en">Doctor of Medical Sciences, Associate Professor, Head of the Department of Therapeutic Dentistry, Federal State Budgetary Educational Institution of Higher Education, Saratov State Medical University (Arkhangelsk), Ministry of Health of the Russian Federation.</span></pre>opravinas@nsmu.ruhttps://orcid.org/0000-0002-0057-3357Soloviev

Andrey Gorgonievich

<pre id="tw-target-text" class="tw-data-text tw-text-large tw-ta" dir="ltr" data-placeholder="Перевод" data-ved="2ahUKEwjh87iEsNWMAxWXHBAIHR7INJkQ3ewLegQICBAV" aria-label="Переведенный текст: Doctor of Medical Sciences, Professor, Head of the Department of Psychiatry and Clinical Psychology, Federal State Budgetary Educational Institution of Higher Education, Saratov State Medical University (Arkhangelsk), Ministry of Health of the Russian Federation."><span class="Y2IQFc" lang="en">Doctor of Medical Sciences, Professor, Head of the Department of Psychiatry and Clinical Psychology, Federal State Budgetary Educational Institution of Higher Education, Saratov State Medical University (Arkhangelsk), Ministry of Health of the Russian Federation</span></pre>asoloviev1@yandex.ruhttps://orcid.org/0000-0002-0350-1359

Northern State Medical University

04112025

1425355

09042025

24042025

2025

<div> <p style="text-align: justify;">Introduction. According to the World Health Organization, 970 million people in the world suffer from various mental illnesses, the manifestations of which often include a decrease in cognitive function and compliance. These factors lead to a deterioration in the level of oral hygiene, high intensity of dental caries and inflammatory periodontal diseases. Natural colonization of normal oral microbiota on periodontal epithelial cells, reflecting the ability of epithelial cells to microbial adhesion, is a sensitive indicator of various destabilizing processes. The level of natural colonization of the gingival epithelium is the degree of contamination of epithelial cells with bacterial cells. Objective of the study: to assess the rate of natural colonization of periodontal epithelial cells in patients with mental illness. Materials and methods of research. The study involved 135 male patients with mental illness and placed in psychoneurological boarding schools in Arkhangelsk. The colonization of epithelial cells was assessed by cytological analysis. The median (Me [Q1, Q3]) was assessed as descriptive statistics. Differences in continuous variables were assessed using the Kruskal-Wallis test. Study results. The average value of the natural colonization of periodontal epithelial cells among subjects with mental illness was 3 [2;4]. The frequency of each indicator in the group of subjects was as follows: indicator 1 occurred in 14.8% of cases, 2 - 32.7%, 3 - 25.7%, and 4 - 26.8%. Conclusion. Thus, the natural colonization of epithelial cells in most subjects corresponded to the average level of 3 [2;4], and a high level was observed in more than a quarter of subjects (26.8%). Such indicators indicate that patients with mental illness have a reduced protective function and resistance of epithelial cells, which leads to increased adhesion of bacteria, mainly cocci, to the cell wall.</p> </div>

epithelial cell natural colonization indexperiodontiummental illness

показатель естественной колонизации эпителиоцитовпародонтпсихическое заболевание

Castrillón E, Castro C, Ojeda A, Caicedo N, Moreno S, Moreno F. Oral Health Status of Hospitalised Patients with Mental Disorders: Systematic Review of the Literature. Estado de salud oral de pacientes hospitalizados con trastornos mentales: Revisión sistemática de la literatura. Rev Colomb Psiquiatr (Engl Ed). Published online June 2, 2020. doi:10.1016/j.rcp.2020.02.001

Sogi GM, Khan SA, Bathla M, Sudan J. Oral health status, self-perceived dental needs, and barriers to utilization of dental services among people with psychiatric disorders reporting to a tertiary care center in Haryana. Dent Res J (Isfahan). 2020;17(5):360-365. Published 2020 Sep 7.

Показатели естественной колонизации буккального эпителия у вегетарианцев / А. Н. Дейнега, А. В. Гостеева, О. Ю. Береснева, Н. М. Жегалина // Актуальные вопросы современной медицинской науки и здравоохранения: Материалы IV Международной научно-практической конференции молодых ученых и студентов, IV Форума медицинских и фармацевтических ВУЗов России "За качественное образование", посвященные 100-летию со дня рождения ректора Свердловского государственного медицинского института, профессора Василия Николаевича Климова, Екатеринбург, 10–12 апреля 2019 года. Том 1. – Екатеринбург: Федеральное государственное бюджетное образовательное учреждение высшего образования "Уральский государственный медицинский университет" Министерства здравоохранения Российской Федерации, 2019. – С. 1120-1124. – EDN JWEDHC.

Алимова, Д. М. Состояние колонизации буккального эпителия у пациентов с рецидивирующим афтозным стоматитом / Д. М. Алимова // International scientific review of the problems of natural Sciences and Medicine: XVIII INTERNATIONAL CORRESPONDENCE SCIENTIFIC SPECIALIZED CONFERENCE, Boston, 02–03 июня 2020 года. – Boston: PROBLEMS OF SCIENCE, 2020. – С.24-28. – EDN DPAOBK.

Определение функциональной активности клеток буккального эпителия у лиц с различным типом питания / О. Ю. Береснева, Н. М. Жегалина, А. Н. Дейнега, А. Б. Гостеева // Клеточные технологии – практическому здравоохранению: Сборник научных работ. Конференция посвящена 80-летию со дня рождения Заслуженного деятеля науки РФ, член-корр., д.м.н., профессора А.П. Ястребова, Екатеринбург, 03–04 декабря 2019 года. – Екатеринбург: Редакция журнала "Вестник Уральской медицинской академической науки", 2019. – С. 214-217. – EDN EEUTOU.