Молодежный инновационный вестник

2415-7805

Федеральное государственное бюджетное образовательное учреждение высшего образования "Воронежский государственный медицинский университет имени Н.Н. Бурденко" Министерства здравоохранения Российской Федерации

10608

Conference Proceedings

Dieulafoy's disease: modern pathological findings

Stupnovich

Diana Vyacheslavovna

studentremol_dobronog@mail.ruhttps://orcid.org/0009-0002-5746-0713Chernikova

Ulyana Sergeevna

studentremol_dobronog@mail.ruhttps://orcid.org/0009-0008-3070-4806

Petrovsky Medical University "Petrovsky National Research Center of Surgery"

25042025

14S1265267

01032025

22032025

2025

Gastrointestinal bleeding (GIB) represents a well-known clinical problem, related both to the risks of developing chronic pathological conditions due to the predominantly recurrent nature of GIB and with life-threatening conditions in cases of acute and severe bleeding. Thus, the necessity of recognizing and addressing hidden sources of bleeding poses new challenges to medicine. For example, the etiopathogenetic and clinical-diagnostic aspects of GIB associated with the formation of abnormal vessels are still not fully studied. One of the most well-known pathological conditions of this type is Dieulafoy's disease the presence of a large vessel of constant diameter, localized in the submucosal or subepithelial layer of a hollow organ, leading to damage to the mucosa, followed by prolapse of the vessel and the development of massive bleeding. Nevertheless, despite the apparent simplicity of the pathogenesis of hemorrhagic syndrome of this type of bleeding, unresolved questions remain related to the development of conditions preceding bleeding, namely, the pathogenesis of vascular malformation and further pathomorphological changes in both the vascular wall itself and the environment of the vessel involved in the pathological process.

Dieulafois diseasegastrointestinal bleedingvascular malformationvascular malformationpathological anatomy

болезнь Дьелафуажелудочно-кишечное кровотечениепорок развития сосудовсосудистая мальформацияпатологическая анатомия

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