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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" article-type="research-article" dtd-version="1.1d1" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher">Молодежный инновационный вестник</journal-id><journal-title-group><journal-title>Молодежный инновационный вестник</journal-title></journal-title-group><issn publication-format="print">2415-7805</issn><publisher><publisher-name>Федеральное государственное бюджетное образовательное учреждение высшего образования "Воронежский государственный медицинский университет имени Н.Н. Бурденко" Министерства здравоохранения Российской Федерации</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">10601</article-id><article-categories><subj-group subj-group-type="heading"><subject>Conference Proceedings</subject></subj-group></article-categories><title-group><article-title>Subareolar lymphatic plexus of Sappey: modern clinical and anatomical interpretation</article-title></title-group><contrib-group><contrib contrib-type="author"><name name-style="western"><surname>Konak</surname><given-names>Maria Alekseyevna</given-names></name><bio>&lt;p&gt;student&lt;/p&gt;</bio><email>remol_dobronog@mail.ru</email><uri content-type="orcid">https://orcid.org/0009-0000-3223-6614</uri><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Beshirova</surname><given-names>Elina Takhirovna</given-names></name><bio>&lt;p&gt;student&lt;/p&gt;</bio><email>remol_dobronog@mail.ru</email><uri content-type="orcid">https://orcid.org/0009-0008-4265-9846</uri><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff id="aff-1">Petrovsky Medical University "Petrovsky National Research Center of Surgery"</aff><pub-date date-type="epub" iso-8601-date="2025-06-30" publication-format="electronic"><day>30</day><month>06</month><year>2025</year></pub-date><volume>14</volume><issue>1</issue><fpage>65</fpage><lpage>68</lpage><history><pub-date date-type="received" iso-8601-date="2025-03-01"><day>01</day><month>03</month><year>2025</year></pub-date><pub-date date-type="accepted" iso-8601-date="2025-03-27"><day>27</day><month>03</month><year>2025</year></pub-date></history><permissions><copyright-statement>Copyright © 2025, Konak M.A., Beshirova E.T.</copyright-statement><copyright-year>2025</copyright-year></permissions><abstract>&lt;p&gt;&lt;span style="font-family: Times New Roman, serif;"&gt;&lt;span style="font-size: large;"&gt;&lt;em&gt;The subareolar lymphatic plexus of Sappey is a part of the dense lymphatic network of the breast, located in the area of ​​the areola of the nipple, formed by deep parenchymatous, intradermal and superficial subcutaneous lymphatic vessels. Numerous literary sources show that over the centuries, the study of the lymphatic system of the breast led various authors to contradictory concepts, which complicated the functional interpretation of the typical and variant lymphangioarchitectonics of the breast, in particular the subareolar lymphatic plexus, first fully described by Constant Marie Philibert Sappey and named in his honor. The study and clinical interpretation of the topographic and anatomical features of the formation of lymphatic outflow links from the breast is extremely important, since lymphogenous metastasis in breast cancer is one of the main ways of tumor dissemination. The aim of the work is a clinical and anatomical substantiation of lymphogenous metastasis of breast cancer, topographically associated with the areolar region. This paper describes the history of the development of views on the lymphangioarchitectonics of Sappey's plexus, describes methodological approaches to its study, concepts describing the formation of the network structure of the plexus, as well as clinical aspects of interpreting the significance of Sappey's lymphatic plexus at the present stage.&lt;/em&gt;&lt;/span&gt;&lt;/span&gt;&lt;/p&gt;</abstract><kwd-group xml:lang="en"><kwd>lymphangioarchitectonics</kwd><kwd>lymphatic plexus of the Sappei</kwd><kwd>subareolar lymphatic plexus</kwd><kwd>Sappei</kwd><kwd>breast cancer</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>лимфангиоархитектоника</kwd><kwd>лимфатического сплетения Саппея</kwd><kwd>субареолярное лимфатическое сплетение</kwd><kwd>Саппей</kwd><kwd>рак молочной железы</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Pan WR, le Roux CM, Levy SM, Briggs CA. 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