Молодежный инновационный вестникМолодежный инновационный вестник2415-7805Федеральное государственное бюджетное образовательное учреждение высшего образования "Воронежский государственный медицинский университет имени Н.Н. Бурденко" Министерства здравоохранения Российской Федерации10509Conference ProceedingsThe effectiveness of biomaterial self-sampling devices in detecting human papillomavirusAseevAlexandr Vadimovichal-aseev@mail.ruhttps://orcid.org/0009-0008-4033-516XKhoperskayaOlga Victorovna<p>PhD, Assistant of the Department of Obstetrics and Gynecology No. 2</p>smv250587@mail.ruhttps://orcid.org/0000-0003-4199-8156EnkovaElena Vladimirovna<p>Doctor of Medical Sciences, Head of the Department of Obstetrics and Gynecology No. 2 of the N. N. Burdenko VSMU</p>enkova@bk.comhttps://orcid.org/0000-0001-8885-1587Voronezh State Medical University named after N.N. Burdenko30062025141462702202527022025Copyright © 2025, Aseev A.V., Khoperskaya O.V., Enkova E.V.2025<p>Cervical cancer currently ranks fourth in the structure of malignant oncological diseases in the world. Breast cancer is one of the most preventable and treatable forms of cancer if it is prevented by vaccination against human papillomavirus (HPV), detected at an early stage and effectively controlled. Russia is the leader among newly identified cases of breast cancer, as indicated by data for 2022, when 127 cases of the disease per 100,000 population [1]. According to the WHO Expert council, about 530,000 new cases of breast cancer are registered annually in the world. Russia is considered the leader among European countries in the number of detected cases between the ages of 29 and 34, as indicated by data from the Global Cancer Observatory [2, 3]. In 2020, WHO developed three strategies for the elimination of breast cancer. These include vaccination of at least 90% of girls against HPV under the age of 15, screening coverage of 70% of women using the highly effective test by the age of 35 and again by the age of 45, as well as treatment of at least 90% of precancerous and breast cancer. Detection of highrisk HPV is an effective screening tool recognized by large international randomized trials. Modern screening programs for the detection of breast cancer face two main problems that require immediate solutions: insufficient coverage of the female population and the need to improve diagnostic methods. Currently, the main focus is on increasing the number of women undergoing screening and optimizing breast cancer screening methods, the most promising of which is the detection of high-risk human papillomavirus (HPV) [4]. Effective screening requires not only a sensitive diagnostic method, but also a broad coverage of the female population by the existing program. However, the unavailability of medical facilities or the fear of diagnostic methods eventually set the task of creating a method of individual diagnostic methods without the direct intervention of a doctor. For this purpose, many vaginal secretion self-sampling test systems have been implemented, which have shown their effectiveness in cohort studies, having high predictive value and the greatest comfort for women.</p>HPVself-samplingQvintipFloqsbiomaterialtest systemsВПЧсамозаборQvintipFloqsбиоматериалтест-системы1.Шахзадова А.О., Старинский В.В., Лисичникова И.В. Состояние онкологической помощи населению России в 2022 году. Сибирский онкологический журнал. 2023;22(5):5–13. https://doi.org/10.21294/1814-4861-2023-22-5-5-13.2.Енькова Е.В., Хоперская О.В., Енькова В.В., Карпова Д.В. Распространенность ВПЧ в популяции женщин города Воронежа. Вопросы практической кольпоскопии. Генитальные инфекции. 2022; (4): 42–45. https://doi.org/10.46393/27826392_2022_4_42.3.Енькова Е.В., Хоперская О.В., Шамарин С.В., Енькова В.В., Асеев А.В. Доказательная медицина: индол-3-карбинол и ресвератрол при состояниях, ассоциированных с вирусом папилломы человека. Медицинский совет. 2024;18(17):74–81. https://doi.org/10.21518/ms2024-398.4.Баширова Л.К., Аполихина И.А., Павлович С.В. Скрининг рака шейки матки с использованием устройства для самозабора материала: эффективность и приемлемость. Акушерство и гинекология. 2020; 2: 50-61 https://dx.doi.org/10.18565/aig.2020.2.50-61.5.Гитман, Т. А. Исследование микробиоты влагалища в материале, полученном с помощью устройства для самостоятельного забора вагинального отделяемого / Т. А. Гитман, Д. Л. Зорников, Е. С. Ворошилина // Актуальные вопросы современной медицинской науки и здравоохранения : сборник статей V Международной (75 Всероссийской) научно-практической конференции. – 2020. – №2. – С.512-516.6.Хрянин А.А., Тапильская Н.И., Кнорринг Г.Ю. Современные представления о папилломавирусной инфекции: эпидемиология и тактика ведения пациентов с аногенитальными бородавками. Клиническая дерматология и венерология. 2020;19(5):719‑728.7.Винокурова С.В. Вирусы папилломы человека 6 и 11 типов: распространенность, патогенность и онкогенность. Вопросы практической кольпоскопии. Генитальные инфекции. 2022; (4): 6–16.8.Леонов М.Г., Артемьева А.С., Ахматханов Х.У. Самозабор влагалищного содержимого – новый метод повышения эффективности скрининга рака шейки матки. Новости клинической цитологии России. 2021; 25(1): 05-08 https://doi.org/10.24412/1562-4943-2021-1-0001.9.Vega Crespo B., Neira V.A., Ortíz S.J., et al. Evaluation of Urine and Vaginal Self-Sampling versus Clinician-Based Sampling for Cervical Cancer Screening: A Field Comparison of the Acceptability of Three Sampling Tests in a Rural Community of Cuenca, Ecuador. Healthcare (Basel). 2022;10(9):1614. Published 2022 Aug 25. doi:10.3390/healthcare10091614.10.Vega-Crespo B., Neira V.A., Maldonado-Rengel R., et al. "Barriers and Advantages of Self-Sampling Tests, for HPV Diagnosis: A Qualitative Field Experience Before Implementation in a Rural Community in Ecuador". Int J Womens Health. 2024;16:947-960. Published 2024 May 28. doi:10.2147/IJWH.S455118.