<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE root>
<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" article-type="research-article" dtd-version="1.1d1" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher">Молодежный инновационный вестник</journal-id><journal-title-group><journal-title>Молодежный инновационный вестник</journal-title></journal-title-group><issn publication-format="print">2415-7805</issn><publisher><publisher-name>Федеральное государственное бюджетное образовательное учреждение высшего образования "Воронежский государственный медицинский университет имени Н.Н. Бурденко" Министерства здравоохранения Российской Федерации</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">10037</article-id><article-categories><subj-group subj-group-type="heading"><subject>Conference Proceedings</subject></subj-group></article-categories><title-group><article-title>Family History Of Autoimmune Polyglandular Syndrome Development</article-title></title-group><contrib-group><contrib contrib-type="author"><name name-style="western"><surname>Solilova</surname><given-names>Anna</given-names></name><email>asolilova@inbox.ru</email><uri content-type="orcid">https://orcid.org/0009-0003-5659-4207</uri><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Novozhilova</surname><given-names>Irina Yurievna</given-names></name><email>asolilova@inbox.ru</email><uri content-type="orcid">https://orcid.org/0000-0002-7275-1407</uri><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff id="aff-1">Ivanovo State Medical University</aff><pub-date date-type="epub" iso-8601-date="2024-12-27" publication-format="electronic"><day>27</day><month>12</month><year>2024</year></pub-date><volume>13</volume><issue>2</issue><fpage>127</fpage><lpage>129</lpage><history><pub-date date-type="received" iso-8601-date="2024-04-16"><day>16</day><month>04</month><year>2024</year></pub-date><pub-date date-type="accepted" iso-8601-date="2024-06-13"><day>13</day><month>06</month><year>2024</year></pub-date></history><permissions><copyright-statement>Copyright © 2024, Solilova A., Novozhilova I.Y.</copyright-statement><copyright-year>2024</copyright-year></permissions><abstract>&lt;p&gt;Introduction. The topic of the development of autoimmune polyglandular syndrome is currently one of the significant in modern endocrinology. Different types of the syndrome are distinguished, but APS type 3 is the most common. One of the causes of the disease development is hereditary predisposition.&lt;/p&gt;&#13;
&lt;p&gt;Objective. To reveal clinical manifestations of autoimmune lesions of endocrine organs and other systems caused by genetic predisposition on the example of one family.&lt;/p&gt;&#13;
&lt;p&gt;Materials and Methods. A prolonged observation of a family with various endocrinopathies of autoimmune genesis was carried out. The patients were examined, anamnestic data and the results of laboratory and instrumental methods of examination were studied. Results. During diagnostic measures such autoimmune diseases were revealed in the mother and three children. as autoimmune thyroiditis, type 1 diabetes mellitus, autoimmune alopecia with associated celiac disease. Conclusions. We determined the presence of genetic predisposition to the development of autoimmune diseases within a single family. Further identification of the prevalence of autoimmune endocrinopathies in families is required to prove the role of heredity, as well as early diagnosis and treatment to improve the quality of life of patients.&lt;/p&gt;</abstract><kwd-group xml:lang="en"><kwd>autoimmune polyglandular syndrome</kwd><kwd>type 1 diabetes mellitus, autoimmune thyroiditis, autoimmune alopecia, celiac disease</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>аутоиммунный полигландулярный синдром</kwd><kwd>аутоиммунный тиреоидит</kwd><kwd>сахарный диабет 1 типа</kwd><kwd>аутоиммунная алопеция</kwd><kwd>целиакия</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>А.А. Ларина, Е.А. Трошина, М.Ю. Юкина. Семейный формы аутоиммунного полигландулярного синдрома 2-го типа: клинический случай // Доктор.Ру. 2019. 10(165). 63-65.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Газизова Г.Р., Шайдулина М.Р., Валеева Ф.В., Галиева А.И. Аутоиммунный полигландулярный синдром 3 типа// Медицинский вестник Юга России. 2020. 11(4). 78-83.</mixed-citation></ref></ref-list></back></article>
