PREVALENCE OF NSAID-ASSOCIATED GASTRITIS AMONG MEDICAL STUDENTS
- Authors: Shchukina E.V.1
-
Affiliations:
- Kursk State Medical University
- Issue: Vol 12, No 1 (2023): Материалы XVII Международной научно-практической конференции молодых ученых-медиков
- Pages: 188-190
- Section: СОВА
- URL: https://new.vestnik-surgery.com/index.php/2415-7805/article/view/8702
Cite item
Full Text
Abstract
Gastritis is an inflammation of the gastric mucosa. There are acute and chronic gastritis. Depending on the causes of the disease, acute and chronic forms of gastritis are distinguished. Acute gastritis occurs as a result of exposure to the gastric mucosa of certain substances (food intoxication, alcohol consumption, spicy, sour and spicy dishes, various medications, etc.).In the acute form of the disease, there is an increase in body temperature, pain and discomfort in the upper abdomen, nausea and vomiting, decreased appetite, diarrhea. Chronic gastritis develops with prolonged irritation of the gastric mucosa from food, alcohol, medicines, chemicals, with diseases of other organs that disrupt digestion (with diseases of the gallbladder, pancreas, intestines). The chronic form of gastritis is characterized by periods of exacerbations and remissions. Acute gastritis is characterized by symptoms such as: pain in the stomach; nausea; vomiting; a feeling of heaviness after eating. With gastritis, the gastric mucosa becomes inflamed. As a result, the digestive process is disrupted, which leads to the development of pain syndrome. This article examines the aspects of awareness of KSMU students concerning NSAID-associated gastritis, the prevalence of this disease is established, the main factors of its occurrence are identified.
Keywords
Full Text
Relevance. NSAID-associated gastritis is a histopathological change in the gastric mucosa under the action of nonsteroidal anti-inflammatory drugs (NSAIDs) taken by a patient to relieve a painful symptom. The main symptom of the disease is epigastric pain, which appears during the period of hunger (usually at night), may be accompanied by nausea, heartburn. The disease can also be asymptomatic [1, 2]. The main diagnostic criterion for diagnosis is to establish the connection of NSAID intake with pathological symptoms, FGDS data. This type of gastritis belongs to the secondary forms of this disease, and therefore, the exclusion of the cause (taking NSAIDs) of the disease leads to its elimination, which explains the relevance of this topic.
Goal. To study the prevalence of NSAID-associated gastritis among medical students of KSMU. Identification of awareness of risk factors for the development of NSAID-associated gastritis. Analysis and synthesis of the obtained data.
Materials and methods. Our research was based on the data obtained as a result of the questionnaire. The survey was conducted among 50 5th-year students of the medical faculty of KSMU.
Results. All respondents participating in the study were offered 8 questions concerning NSAID-associated gastritis. During the study, it was found: the ratio of male and female, how many times a month students take NSAIDs, do you use proton pump inhibitors (omeprozole) together with NSAIDs, for what reason students take NSAIDs, is there a diagnosed NSAID gastritis, do students worry about "hungry" pains, heartburn, acid belching, have you noticed whether students have plaque on their tongue, what factors may predispose to the occurrence of NSAID-associated gastritis.
The study involved 50 students, 75% of them women, 25% men. Students take NSAIDs: 1-2 times a month - 60%; 3-4 times a month – 25%; 5 times or more – 15%. Respondents use proton pump inhibitors together with NSAIDs in 65% of cases. The reasons for taking NSAIDs: for relieving headaches – 45%, for relieving painful menstruation – 55%. The diagnosis of NSAID gastritis was established in 15% of respondents. Some students note the following symptoms: "hunger pains" - 5%, heartburn – 25%, acid belching – 5%, plaque on the tongue – 5%. As a risk factor for the occurrence of NSAID gastritis, students chose to take nonsteroidal anti–inflammatory drugs - 100%.
Conclusions. As a result of the study, it was found that the majority of students take NSAIDs 1-2 times a month (60%) to relieve headaches (45%) and painful menstruation (55%). The majority of respondents (65%) take proton pump inhibitors together with NSAIDs. 15% of the respondents were diagnosed with NSAID-associated gastritis. All students believe that the main risk factor for NSAID-associated gastritis is taking nonsteroidal anti-inflammatory drugs. All this suggests that most students are aware of this problem and try to avoid it by taking proton pump inhibitors together with NSAIDs.
About the authors
Ekaterina Viktorovna Shchukina
Kursk State Medical University
Author for correspondence.
Email: yekaterina.schukina123@yandex.ru
ORCID iD: 0009-0003-4323-267X
Russian Federation, 3, K. Markx str., Kursk, 305000, Russia
References
- Циммерман, Я.С. Поражение желудка, индуцированное приемом нестероидных противовоспалительных препаратов (НПВП): НПВП-гастрит или НПВП-гастропатия? / Циммерман Я.С. // Клиническая фармакология и терапия. - 2018. - Т. 27. - № 1. - С. 14-21.
- Вельц, Н.Ю. Нестероидные противовоспалительные препараты: проблемы безопасности применения / Н.Ю. Вельц, Е.О. Журавлева, Т.М. Букатина, Г.В. Кутехова // Безопасность и риск фармакотерапии. - 2018. - Т. 6. - № 1. - С. 11-18.


