Vol 6, No 2 (2003)

It has been suggested that informational components of thinking, consciousness and memory were considered as major components of aging rate regulation.

The results have been reported on the treatment of 1079 children, aged 1 to 15 years old, with acute lymphoblastic leucosis in the centers of pediatric oncohematology in the period from 1991 to 1998. The patients were administered the program treatment according to the modified protocol ALL-BFM-90m, 107 children received non-program treatment. Within the framework of the protocol the patients were divided into groups with standard, mean and high risk (respectively 29.0%; 63.2%; 7.1%), which determined the volume of polychemotherapy and radiation therapy. The treatment results were assessed according to the indices of overall (OS) and event-free (EFS) survival rate using the method of Kaplan-Mayer. The remission was observed in 84-92% of cases. Treatment tolerance was wholly satisfactory. Five-year event-free survival rate (EFS) made up 0.63; 0.72; 0.5 correspondingly depending on the risk group. The advantages of five-year program treatment of acute lymphoblastic leukosis were seen in the results of overall survival rate (OS-0.69), considerably exceeding similar results in the group of patients, administered non-program treatment (OS - 0.32). Infectious complications against the background of neutropenia (29%) and viral hepatitis (45%) were a menace to the lives of patients. Recurrences still remain the main cause of failures happening in the course of treatment according to the protocol ALL-BFM-90 m. It was identified that the causes of acute lymphoblastic leukosis development, features of its localization, and course and recurrence outcomes in children are associated with pathological process severity and non-adequate treatment administered at the initial disease stage. The indices of event-free survival rate, according to the results of our investigations, conform to the general tendency of five-year survival rate growth in children with acute lymphoblastic leucosis. The program therapy for acute lymphoblastic leucosis administered to children according to the protocol ALL-BFM-90m is more efficient than non-program treatment. *Centers of pediatric oncohematology were established in Russia in 1991 in the following cities: Vladivostok, Volgograd, Voronezh, Yekaterinburg, Rostov-on-Don, Novosibirsk, Novokuznetsk, Omsk, Habarovsk with the support of charitable Foundation “Care”, Germany.

It has been identified that there are metabolic, endocrine and immunological causes resulting in the development of some inactive endometrial elements, containing in the blood flown backward, into invasive tumor with penetrating growth, such as minor forms of endometriosis.

Propose the algorithme of pharmacoimmunocorrection of infections urogenitales

Controlled treatment methods have been developed for mental diseases on the grounds of quantitative assessment of differential thermometric indices of biologically active points. This enabled to work out the decision-making algorithms while treating schizophrenia and endogenous depressions with the use of modern psychotropic medications, which led to the reduction of hospital stay by 3 to 5 days.

The treatment method have been presented for patients with complex clinical conditions of prosthetic bed; the structures of removable laminar dentures with basis elastic layer, their functional resources and features of manufacturing techniques of dentures of different modifications have been described.

Microsurgical autotransplantation of tissue complexes is an optimal method of defect replacement, occurring as a result of surgical treatment of locally advanced primary and recurrent malignant tumors of facial and scalp integuments, it enables to obtain positive functional and esthetic results in a comparatively short time period, which is the major condition of valuable social and psychological rehabilitation.

Application of complex diagnostic and complex treatment methods enables to set the diagnosis in the shortest possible time and to undertake timely and competent correction measures for oral mucosa and periodontum pathological states of inflammatory origin, identified at clinical stages of orthodontic treatment of dentitions.

Delivering dental services to Navy personnel it is required to take into account high incidence rate of dental diseases both among fresh forces and people serving on contractual basis, insufficient sanation procedures administered to draftees, low level of preventive measures, performed by military unit dentists.

Examinations have been conducted on 50 teeth of the frontal group directly in oral cavities, chromaticity coordinates were identified of cervical area, body and cutting edge of different teeth. The analysis of measurument results allows the consumption that all the spectra have different shapes; on chromaticity diagram each spectrum corresponds to its own coordinate point. Objective color difference was identified between cervical area, body area and cutting edge per units of color threshhold.

The authors have improved the quality of diagnosis and treatment of patients with severe and compound facial injuries, widely applying surgical method of reposition and fixation of facial bones and taking into account the features of craniofacial injury in the child age.

The method of delayed scheduled video thoracoscopy may be recommended for application in hospitals, unable to provide for twenty-four-hour video thoracoscopic services. Using the methods suggested we have not ever had a single clotted hemothorax occurring in the hospital. All patients, having surgery due to such a diagnosis were admitted from other medical establishments.

The issues have been considered of alimentary-dependant sickness prevention. For the last years dozens of recipes and technologies have been developed for foodstuffs of special value, used in prevention and complex treatment of alimentary diseases.

The final objective of information delivery to regional public health establishment of lower level should include the development and introduction of the so-called “electronic passport of a patient” containing, apart from the patient’s passport data, the complex of treatment and diagnostic measures, administered to a patient during the life period.