Vol 2, No 4 (1999)

The materials of experimental research work and theoretical basis of bioresonance therapy use are adduced. Bioresonance therapy allows to use and intensify organism’s physiological processes, almost solving the problem of medicinal therapy complications and carrying out dynamic control whole curing a patient. This, undoubtedly, increases the efficiency of treatment.

The analysis of versatile surgical hospital activity in 1997-1999 years was made. It was found out that the predominance of a kind of treatment - conservative or operating, volume of each patients examination varies greatly depending on the economical platform of hospitalization. So, at the charge-free service the resources of medical entity are spent not always rationally. In a surgical hospital the volumes of conservative treatment and operating are approximately identical and 50% more examinations for 1 patient independently of how serious the desease is. In case of paid service only conservative treatment is met extremely seldom, operational powers and the surgical proficiency of the doctors is used more rationally. And quantity of complications and relapses in patients does not depend on what economical basis they been given help. Using organizational technology of an optimum ratio of volumes of the paid and charge-free help it is possible, to increase the effectivity of surgical hospital work and to improve the quality of medical help.

Experimental research data of a number of synthesized Local Anaestheties are shown. Until now only the similarity of structure and strengthening of antiarrhytmmie properties after changing aminoalcoxyl chain structure in blokers of Na+ channels were not known. We have proved that the introducing of one benzol ring into the 1-2-3-position of methoxy-group or changes of the aliphatic chain lead to the pharmacological activity changes. Studying connection between the structure and the effect of the medicine one must take into consideration the mesomeric effect as one of the factors reshaping biological potency of carbonyl and its subsequent effect on the cell receptors’ active centres. Later it is advisable to conduct direct -chemical calculations of electronic structure of medicines under analysis and Local Anaesthetics showing the same effect. It will let us quantatively estimate the structure of receptor’satisfactory active centre in biomembrane and introduce the new criteria for prognosing anaesthetics’ biological potency.

The outcome of examination of 153 patients with the stomach adenocarcinoma are submitted. Black acanthosis is observed in 9 cases. Sex distribution has compounded men 6, women 3. The majority of patients were older than 60 years. 8 patients had the 2-nd and the 3-d stage of tumoral process one-generalized form of stomach carcinoma. 8 patients were given radical treatment, one was made tentative laparotomy. The controlling inspections 3 and 6 months later revealed the regress of paraneoplastic process in the majority of patients. In 5 patients the black acanthosis has preceded to the clinical development of tumor for the term from 4 months till 3 years in remaining paraneoplastic syndrome developed simultaneously with the clinical development of tumor. The conclusion is that the early diagnostic of tumoral process in patients with black acanthosis could promote more well-timed therapy and improvement of long-term results of treatment.

The outcome of examination of 189 patients with stomach carcinoma is analyzed in the article. In 10 people tumor was combined with rheumatic syndrome. The conducted research testifies to its paraneoplastic nature. In the majority of cases rheumatic syndrome has preceded a clinical development of tumor. The distribution of the patients is following: 4 patients with the 1-st and the 2-nd stages and 6 with the 3-d and 4-th stages of tumoral process. The conclusion is that the early diagnostic of stomach carcinoma, based on paraneoplastic nature of rheumatic syndrome could change tactics of treatment and distant forecast of life for the majority of patients of described group.

More than 500 case histories of patients taking treatment on surgic hospital have been analysed. It was revealed that twin organs showed statistically different frequency of right- or leftside localization of the pathological process. The difference concerns both nosological classes of diseases (IDS 10) and anatomical localization of pathological nidus (head, upper extremities, trunk, lower extremities). These facts with some amount of subjective estimate deserve more detailed studying and may become the basis for prognosing morbidity and prophylactic measures recommendation.

In research the analysis of condition of vegetative homeostasis in patients with disturbing-depressive distress is carried out to increase the efficiency of their medicamental therapy. It was ascertained that early detection and correction of disturbance of vegetative homeostasis at disturbing-depressive distress have the relevant preventive value from stands of psychosomatic medicine.