Vol 26, No 1 (2023): Опубликован 29.03.2023

A dentist-surgeon performs a large number of different surgical procedures. Despite the fact that in the 21st century, the level of dental care is high, the number of tooth extractions has not decreased. The main component of surgical work is the extraction of a tooth.

The article analyzes the clinical and radiological control of the process of socket regeneration using A-PRF technology, in addition, an assessment of the opinion of doctors on the use of this technique of “hole preservation” after removal was carried out.

In his practice, a dental surgeon often encounters complications after a tooth extraction operation, and in order to avoid them, it is necessary to carry out a set of measures aimed at improving the rehabilitation period, optimizing the reparative process and improving the results of surgical treatment.

Based on the results of our work, we found that this technique is not popular among doctors, although it shows good results. When using A-PRF clot, the period of socket epithelialization is reduced, and early formation of a bone pattern is observed, which we do not observe in patients in whom this technique is not used.

In order not to carry out repeated surgical reception in the future, it is necessary to think about early conservation.

Inflammatory periodontal diseases remain an unsolved problem of modern medicine due to the high prevalence and insufficient effectiveness of treatment. The study examined the effectiveness of photodynamic and anti-inflammatory therapy in the treatment of chronic generalized periodontitis of moderate severity. The study material was the results of a comprehensive dental examination and treatment of 90 patients aged 30 to 49 years. For treatment, Asepta balm, photodynamic therapy (FotoSan 630 device), etoricoxib (Arcoxia) were used for follow-up periods of up to six months using periodontal indices. The high efficiency of treatment of chronic generalized periodontitis of moderate severity with a combination of photodynamic and anti-inflammatory therapy has been proven. This combination increased the effectiveness of treatment, compared with single-component antimicrobial therapy by 29.9%.

Improving the reliability of fixing fixed orthopedic structures of dentures is an urgent issue at all times. Due to the increase in the variety of materials in the modern world, the choice for dentists has become even more difficult. Various types of fixing materials are used in the clinic, and their choice depends on the specifics of the clinical situation and the material of the structure from which it is made.

One of the types of cements are zinc-phosphate, which are used in practice for a long time and are characterized by sufficient adhesion strength. Representatives of this group have become less popular in the orthopedic dental clinic, since its properties are considered insufficiently satisfactory. Undoubtedly, any fixing material has both pros and cons. It is possible to get high-quality treatment with a dental prosthesis in the oral cavity if the fixing materials are correctly selected, the principles of preparation are observed and a high-quality adhesive protocol is performed.

The article describes a study of the adhesive ability of individual zinc-phosphate cements, which was carried out in laboratory conditions at the technical base of LLC "Tselit" Voronezh. 30 teeth of the chewing group were used, which were divided into groups according to the use of materials: "NeoDent" LLC Celit, "VISCIN" LLC Raduga-R, "Adhesor" SpofaDental (Czech Republic).

The strength of adhesion was studied using the method - shear test, which determines the strength of the connection of dentine tissue with zinc-phosphate cement.

The data of domestic and foreign literature characterizing the current state of pharmaceutical education are studied. The criteria for the effectiveness of the process of professional development of pharmaceutical industry specialists have been established. A sociological study of pharmaceutical workers on the demand and quality of pharmaceutical education received by them was conducted. Practical recommendations aimed at improving the process of professional development of pharmaceutical workers to improve the quality of pharmaceutical care are proposed.

The aim of the work was to create a piezoelectric sensor modified with a polymer with molecular imprints of cefuroxime for its subsequent determination in aqueous solutions. For the synthesis of MIP, we used a mixture containing a copolymer of 1,2,4,5-benzenetracarboxylic acid and 4,4'-diaminodiphenyl oxide produced by OJSC IIPP SPA «Plastic» (Moscow), as well as a solution containing template molecules.

The resulting mixture was applied to the surface of the sensor electrode by stamping. After that, thermal imidization was carried out in an oven. Next, the sensors were cooled and placed in distilled water to remove the template.

The resulting sensor was used to determine the content of the antibiotic cefuroxime in aqueous solutions using a calibration curve. For this, standard solutions of cefuroxime were prepared with concentrations of 1.0•10–1 – 1.0•10–7 g/dm³. The measurements made allowed us to conclude that with an increase in the antibiotic concentration in the analyzed solution, a decrease in the resonant frequency occurs. The calibration dependence is linear. The limit of detection of cefuroxime for the obtained sensor is 1.0•10–5 g/dm3. To test the selectivity of the obtained sensor based on a polymer with molecular imprints, an analysis of an antibiotic similar in structure, cefazolin, was carried out. It has been established that the sensory system is selective only for the antibiotic that was used for the synthesis of MIP.