<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE root>
<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" article-type="research-article" dtd-version="1.1d1" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher">Applied Information Aspects of Medicine (Prikladnye informacionnye aspekty mediciny)</journal-id><journal-title-group><journal-title>Applied Information Aspects of Medicine (Prikladnye informacionnye aspekty mediciny)</journal-title></journal-title-group><issn publication-format="electronic">2070-9277</issn><publisher><publisher-name>Voronezh State Medical University named after N.N. Burdenko - The State Budgetary Institution of Higher Professional Education «Voronezh State Medical University named after N.N. Burdenko» of the Ministry of Public Health of the Russian</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">9106</article-id><article-id pub-id-type="doi">10.18499/2070-9277-2023-26-2-40-45</article-id><article-categories><subj-group subj-group-type="heading"><subject></subject></subj-group></article-categories><title-group><article-title>STUDY OF CLINICAL AND MICROBIOLOGICAL PARAMETERS IN PATIENTS WITH NON-REMOVABLE ORTHODONTIC EQUIPMENT DURING THE USE OF DENTAL GELS IN A COMPARATIVE ASPECT</article-title></title-group><contrib-group><contrib contrib-type="author"><name name-style="western"><surname>Lesteva</surname><given-names>Anastasia G.</given-names></name><email>strusovskaya.a@yandex.ru</email></contrib><contrib contrib-type="author"><name name-style="western"><surname>Firsova</surname><given-names>Irina V.</given-names></name><email>firsstom@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Strusovskaya</surname><given-names>Olga G.</given-names></name><email>Strol3@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff id="aff-1"></aff><pub-date date-type="epub" iso-8601-date="2023-06-27" publication-format="electronic"><day>27</day><month>06</month><year>2023</year></pub-date><volume>26</volume><issue>2</issue><fpage>40</fpage><lpage>45</lpage><history><pub-date date-type="received" iso-8601-date="2023-07-01"><day>01</day><month>07</month><year>2023</year></pub-date><pub-date date-type="accepted" iso-8601-date="2023-07-01"><day>01</day><month>07</month><year>2023</year></pub-date></history><permissions><copyright-statement>Copyright © 2023, Applied Information Aspects of Medicine (Prikladnye informacionnye aspekty mediciny)</copyright-statement><copyright-year>2023</copyright-year></permissions><abstract>&lt;p&gt;Inflammatory periodontal disease is the second most common pathology after dental caries, affecting up to 95% of the population of different age groups. The main etiological factor in the occurrence of this pathology is periodontopathogenic microflora. During orthodontic intervention, there is an exacerbation of inflammatory processes in the periodontium due to the accumulation of microbial biofilm, due to the appearance in the oral cavity of patients of additional retention sites in the form of fixed structures. The use of conventional hygiene products is not enough to eliminate deposits of microbial origin. Therefore, to reduce the inflammatory process in the periodontium during orthodontic intervention, it is necessary to use additional hygiene products that provide an adequate antimicrobial effect. These funds should mainly have a specific effect on the periodontopathogenic microflora. In the course of the conducted studies, the effectiveness of the antimicrobial action of dental gels "Bergisept" and "Metrogil-Denta" was proved. At the same time, "Bergisept-gel" has the advantages of specifically inhibiting the growth of P. gingivalis and A. actinomycetemcomitans and practically does not have an antimicrobial effect against Str. salivarius.&lt;/p&gt;</abstract><kwd-group xml:lang="en"><kwd>periodontopathogenic microflora</kwd><kwd>orthodontic treatment</kwd><kwd>inflammatory periodontal diseases</kwd><kwd>antibacterial effect</kwd><kwd>dental gel.</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>пародонтопатогенная микрофлора</kwd><kwd>ортодонтическое лечение</kwd><kwd>воспалительные заболевания пародонта</kwd><kwd>антибактериальное действие</kwd><kwd>стоматологический гель.</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Аверьянов С. В. Взаимосвязь между зубочелюстными аномалиями и заболеваниями пародонта / С. В. Аверьянов, А. В. Зубарева // Проблемы стоматологии. – 2015. – № 2. – С. 46.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Заркумова А. Е. Структура заболеваемости слизистой оболочки полости рта / А. Е. Заркумова // Вестник КазНМУ. – 2017. – № 3. – С. 166-173.</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Керефова З. В. Влияние ортодонтического лечения на состояние тканей пародонта (обзор литературы) / З. В. Керефова, М. Т. Тхазаплижева, К. А. Шхагапсоева, [ и др.] //Современная наука: актуальные проблемы теории и практики. Серия: естественные и технические науки. – 2021. – Т. 8. – С. 174-179.</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>Лукичев М. М. Современные представления о роли микрофлоры в патогенезе заболеваний пародонта / М. М. Лукичев, Л. А. Ермолаева // Институт стоматологии. – 2018. – № 1. – С. 92 – 94.</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>Олейник Е. А. Современные аспекты консервативного подхода к лечению воспалительных заболеваний пародонта у пациентов молодого, среднего и пожилого возраста / Е. А. Олейник, И. А. Беленова, О. И. Олейник, [и др.] // Актуальные проблемы медицины. – 2022. – Т. 45, №2.– С. 178 – 197.</mixed-citation></ref><ref id="B6"><label>6.</label><mixed-citation>Романова Р. О. Особенности формирования микробной биопленки при воспалительных заболеваниях пародонта / Р. О. Романова, М. Е. Кашлевская, Д. С. Левенков, [и др.] // Вестник ПензГУ. – 2022. – Т. 37, № 1. – С. 19 – 23.</mixed-citation></ref><ref id="B7"><label>7.</label><mixed-citation>Тимошин А. В. Опыт лечения воспалительных заболеваний тканей пародонта препаратами на основе коллагена и дигестазы / А. В. Тимошин, А. В. Севбитов, Е. В. Ергешева, Ю. Л. Васильев // Медицинский алфавит. – 2018. – Т. 2, №1. – С. 6 – 10.</mixed-citation></ref><ref id="B8"><label>8.</label><mixed-citation>Флейшер Г. Некоторые факты о гигиене полости рта при ортодонтическом лечении / Г. Флейшер // Руководство для врачей. – Litres. – 2022. – 70 с.</mixed-citation></ref><ref id="B9"><label>9.</label><mixed-citation>Fernandez-Gutierrez, M. M. Streptococcus salivarius MS-oral-D6 promotes gingival re-epithelialization in vitro through a secreted serine protease / M. M. Fernandez-Gutierrez, P. P. Roosjen, E. Ultee, M. Agelink [et al.] // Scientific reports. – 2017. – Vol. 7, Iss. 1. – P. 1-15.</mixed-citation></ref><ref id="B10"><label>10.</label><mixed-citation>MacDonald, K. W. Streptococcus salivarius inhibits immune activation by periodontal disease pathogens / K. W. MacDonald, R. M. Chanyi, J. M. Macklaim, P. A. Cadieux [et al.] // BMC Oral Health. – 2021. – Vol. 21. – Iss. 1. – C. 1–16.</mixed-citation></ref></ref-list></back></article>
