Applied Information Aspects of Medicine (Prikladnye informacionnye aspekty mediciny)Applied Information Aspects of Medicine (Prikladnye informacionnye aspekty mediciny)2070-9277Voronezh State Medical University named after N.N. Burdenko - The State Budgetary Institution of Higher Professional Education «Voronezh State Medical University named after N.N. Burdenko» of the Ministry of Public Health of the Russian788110.18499/2070-9277-2021-24-4-58-64Original ArticleTHE EFFICIENCY OF USING A CELLULOSE-BASED TEST SYSTEM FOR THE RAPID DIAGNOSIS OF BACTERIAL VAGINOSIS. (IN PATIENTS OF REPRODUCTIVE AGE BASED ON CHANGES IN THE PH OF VAGINAL DISCHARGE)ZolotukhinV. O.-KhoroshikhN. V.-ZolotukhinO. V.-MadykinYu. Yu.-MittovaV. O.-Voronezh N.N. Burdenko State Medical University15122021244586428092022Copyright © 2021, Applied Information Aspects of Medicine (Prikladnye informacionnye aspekty mediciny)2021Currently, one of the most common causes of vaginal microbiota disorders is bacterial vaginosis, detected in 80-87% of women with pathological vaginal secretions. During the initial stages of the development of the disease, bacterial vaginosis is accompanied by very poor symptoms, which makes it difficult to diagnose it early. A change in the pH of vaginal secretions can serve as an early symptom of developing bacterial vaginosis, and the determination of the pH of vaginal secretions is regulated by modern Russian and foreign guidelines as a mandatory diagnostic study of women with pathological leucorrhoea. For the continuous determination of the pH of the vaginal discharge, we proposed a test system with an adsorption chip based on cotton cellulose modified by an indicator. The purpose of this study was the evaluation of the efficiency of the obtained test system for the rapid diagnosis of the presence of bacterial vaginosis in women.bacterial vaginosistest systemsgynaecologyБактериальный вагинозтест-системыгинекология[Ефимов Б.А., Тютюнник В.Л. Бактериальный вагиноз: современный взгляд на проблему // РМЖ. 2008. T. 16(1). C. 18-22. @@ Efimov B.A., Tyutyunnik V.L. Bacterial vaginosis: a modern view of the problem. // RMJ. 2008. Vol.16(1). P. 18-22][Бактериальный вагиноз //Кира Е.Ф. М.: МИА, 2012. 472 c. Изд. 2-е, испр., доп. @@Bacterial vaginosis // Kira E.F. Second Edition. Moscow: MIA; 2012. 472p.][Mania-Pramanik J, Kerkar SC, Mehta PB, Potdar S, Salvi VS. Use of vaginal pH in diagnosis of infections and its association with reproductive manifestations // J Clin Lab Anal. 2008. Vol. 22(5). P. 375-379.][Pereira S.D., Martinez O.J., Negreiro F. Observational study of vaginal pH in healthy Portuguese women // Minerva Ginecol 2011. Vol. 63 (2). P. 203-12.][Патент РФ: «Прокладка-индикатор для диагностики заболеваний репродуктивной системы человека» Номер патента: RU 200701 U1 от 6.11.2020 г. @@Patent of the Russian Federation: "Indicator strip for the diagnosis of diseases of the human reproductive system" Patent number: RU 200701 U1 date6.11.2020][Савичева А. М., Тапильская Н. И., Шипицына Е. В., Воробьева Н. Е. Бактериальный вагиноз и аэробный вагинит как основные нарушения баланса вагинальной микрофлоры. Особенности диагностики и терапии // Акушерство и гинекология. 2017. Т. 5. С. 24-31 @@Savicheva A.M., Tapilskaya N. I., Shipitsyna E. V., Vorobyeva N. E. Bacterial vaginosis and aerobic vaginitis as major vaginal microflora balance disorders: Diagnostic and therapeutic characteristics // Obstetrics and gynecology. 2017. Vol. 5. P. 24-31][Bagnall P., Rizzolo D. Bacterial vaginosis: A practical review // JAAPA. 2017. Vol. 30. P. 15-21.][Sherrard J., Wilson J., Donders G, Mendling W., Jensen J. S. European (IUSTI/WHO) International Union against sexually transmitted infections (IUSTI) World Health Organisation (WHO) guideline on the management of vaginal discharge // International Journal of STD & AIDS. 2018. Vol. 29. P. 1258-1272.][Малова И. О., Афанасьева И. Г., Гусевская К. А. Острые вагиниты смешанной этиологии: современный подход к лечению // Акушерство и гинекология: Новости, мнения, обучение. 2019. Т. 7. C. 79-86 @@Malova I. O., Afanasyeva I. G., Gusevskaya K. A. Acute vaginitis of mixed etiology: a modern approach to treatment // Obstetrics and gynecology: News, opinions, training. 2019. Vol. 7. P. 79-86][Диагностика инфекций в акушерско-гинекологической и неонатологической практике: учебное пособие. // Москва, Радугаc 2018. 124 с. @@Diagnosis of infections in obstetric-gynecological and neonatology practice: textbook. // Moscow, Raduga, 2018, 124 p.]