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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" article-type="research-article" dtd-version="1.1d1" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher">Applied Information Aspects of Medicine (Prikladnye informacionnye aspekty mediciny)</journal-id><journal-title-group><journal-title>Applied Information Aspects of Medicine (Prikladnye informacionnye aspekty mediciny)</journal-title></journal-title-group><issn publication-format="electronic">2070-9277</issn><publisher><publisher-name>Voronezh State Medical University named after N.N. Burdenko - The State Budgetary Institution of Higher Professional Education «Voronezh State Medical University named after N.N. Burdenko» of the Ministry of Public Health of the Russian</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">7871</article-id><article-id pub-id-type="doi">10.18499/2070-9277-2021-24-2-40-45</article-id><article-categories><subj-group subj-group-type="heading"><subject>Original Article</subject></subj-group></article-categories><title-group><article-title>DEVELOPMENT OF DOSAGE FORMS FOR TREATMENT OF INFLAMMATORY DISEASES OF PERIODONTAL TISSUES AND ORAL DYSBIOSIS</article-title></title-group><contrib-group><contrib contrib-type="author"><name name-style="western"><surname>Vecherkina</surname><given-names>J. V</given-names></name><bio></bio><email>-</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Chirkova</surname><given-names>N. V</given-names></name><bio></bio><email>-</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Peleshenko</surname><given-names>E. I</given-names></name><bio></bio><email>-</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Bobeshko</surname><given-names>M. N</given-names></name><bio></bio><email>-</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff id="aff-1">Voronezh State Medical University</aff><pub-date date-type="epub" iso-8601-date="2021-12-15" publication-format="electronic"><day>15</day><month>12</month><year>2021</year></pub-date><volume>24</volume><issue>2</issue><fpage>40</fpage><lpage>45</lpage><history><pub-date date-type="received" iso-8601-date="2022-09-28"><day>28</day><month>09</month><year>2022</year></pub-date></history><permissions><copyright-statement>Copyright © 2021, Applied Information Aspects of Medicine (Prikladnye informacionnye aspekty mediciny)</copyright-statement><copyright-year>2021</copyright-year></permissions><abstract>Inflammatory periodontal diseases are widespread, requiring a comprehensive approach in formulating a treatment plan. Often, the main etiological factor of these diseases is the development of dysbiotic processes in the oral cavity. There are few dosage forms designed to eliminate these problems on the market today. The aim is to develop a formulation of a gingival bandage with a probiotic or symbiotic in gel form with an extended spectrum of therapeutic effect, prolonged action, convenient in use, allowing to distribute the active substance evenly on periodontal tissues and oral mucosa to improve the quality of complex treatment of patients with inflammatory and dysbiotic phenomena of the oral cavity.</abstract><kwd-group xml:lang="en"><kwd>periodontal diseases</kwd><kwd>dysbiotic processes</kwd><kwd>dressing gum paste formulation</kwd><kwd>probiotic</kwd><kwd>symbiotic</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>заболевания пародонта</kwd><kwd>дисбиотические процессы</kwd><kwd>рецептура десневой пасты - повязки</kwd><kwd>пробиотик</kwd><kwd>симбиотик</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Оценка эффективности комплексного лечения и комплаентности пациентов с заболеваниями тканей пародонта / Чиркова Н.В., Плутахина А.А., Петросян А.Э., Андреева Е.А., Бобешко М.Н.// Системный анализ и управление в биомедицинских системах. - Т. 19, № 4. 2020. - С. 42-55 @@Evaluation of the effectiveness of complex treatment and compliance of patients with periodontal tissue diseases / Chirkova N.V., Plutakhina A.A., Petrosyan A.E., Andreeva E.A., Bobseko M.N.// System analysis and management in Biomedicine systems. - T. 19, No. 4. 2020. - P. 42-55</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Профилактика стоматологических заболеваний: учебное пособие / С.И. 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