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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" article-type="research-article" dtd-version="1.1d1" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher">Applied Information Aspects of Medicine (Prikladnye informacionnye aspekty mediciny)</journal-id><journal-title-group><journal-title>Applied Information Aspects of Medicine (Prikladnye informacionnye aspekty mediciny)</journal-title></journal-title-group><issn publication-format="electronic">2070-9277</issn><publisher><publisher-name>Voronezh State Medical University named after N.N. Burdenko - The State Budgetary Institution of Higher Professional Education «Voronezh State Medical University named after N.N. Burdenko» of the Ministry of Public Health of the Russian</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">7857</article-id><article-id pub-id-type="doi">10.18499/2070-9277-2022-25-2-15-19</article-id><article-categories><subj-group subj-group-type="heading"><subject>Original Article</subject></subj-group></article-categories><title-group><article-title>ROLE OF CHOLECALCIFEROL IN BONE RESORPTION OF ALVEOLAR PROCESSES IN PATIENTS WITH CHRONIC GENERALIZED PERIODONTITIS AND PARTIAL ADENTIA</article-title></title-group><contrib-group><contrib contrib-type="author"><name name-style="western"><surname>Polushkina</surname><given-names>A. A</given-names></name><bio></bio><email>-</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Bobeshko</surname><given-names>M. N</given-names></name><bio></bio><email>-</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff id="aff-1">Voronezh State Medical University</aff><pub-date date-type="epub" iso-8601-date="2022-12-15" publication-format="electronic"><day>15</day><month>12</month><year>2022</year></pub-date><volume>25</volume><issue>2</issue><fpage>15</fpage><lpage>19</lpage><history><pub-date date-type="received" iso-8601-date="2022-09-28"><day>28</day><month>09</month><year>2022</year></pub-date></history><permissions><copyright-statement>Copyright © 2022, Applied Information Aspects of Medicine (Prikladnye informacionnye aspekty mediciny)</copyright-statement><copyright-year>2022</copyright-year></permissions><abstract>Diseases of the human oral cavity have acquired such a large scale that they give reason to talk not only about the problem of a purely medical, but also of a social nature. Periodontal diseases occur in almost all people over 40 years of age (WHO experts, 2006), including in industrialized countries. According to various sources, 90% of the population show signs of gingivitis, 50% and 3% - symptoms of moderate and severe periodontitis, respectively. At the same time, a severe course of periodontitis is increasingly noted with an increase in the number of patients with aggressive forms of the disease. Disturbance of hormone formation and their deficiency can cause the development of periodontal pathology. The deficiency of one of them D-hormone, which is called cholecalciferol, which has a wide range of biological properties and is involved in the regulation of many important physiological processes, also has negative consequences and underlies a number of diseases. Until recently, the most studied property of cholecalciferol was its regulation of calcium-phosphorus homeostasis. However, new data from domestic and foreign authors allow us to expand our ideas about the true influence of this hormone-like substance on a variety of biological effects.</abstract><kwd-group xml:lang="en"><kwd>dentistry</kwd><kwd>periodontitis</kwd><kwd>gingivitis</kwd><kwd>therapeutic and preventive measures</kwd><kwd>vitamin and mineral complex</kwd><kwd>diabetes mellitus</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>стоматология</kwd><kwd>пародонтит</kwd><kwd>гингивит</kwd><kwd>лечебно-профилактические мероприятия</kwd><kwd>витаминно-минерального комплекса</kwd><kwd>сахарный диабет</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Голубев Н. А., Чиркова Н. В., Полушкина Н. А., Плотникова И. Е., Бобешко М. Н. Современные аспекты гигиены полости рта у больных пользующихся съемными протезами // Системный анализ и управление в биомедицинских системах. 2016. Т. 15, №2. С. 248-250. @@Golubev N. A., Chirkova N. 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