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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" article-type="research-article" dtd-version="1.1d1" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher">Applied Information Aspects of Medicine (Prikladnye informacionnye aspekty mediciny)</journal-id><journal-title-group><journal-title>Applied Information Aspects of Medicine (Prikladnye informacionnye aspekty mediciny)</journal-title></journal-title-group><issn publication-format="electronic">2070-9277</issn><publisher><publisher-name>Voronezh State Medical University named after N.N. Burdenko - The State Budgetary Institution of Higher Professional Education «Voronezh State Medical University named after N.N. Burdenko» of the Ministry of Public Health of the Russian</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">7704</article-id><article-id pub-id-type="doi">10.18499/2070-9277-2021-24-3-38-42</article-id><article-categories><subj-group subj-group-type="heading"><subject>Original Article</subject></subj-group></article-categories><title-group><article-title>ENVIRONMENTAL FACTORS AND FORMATION OF THE DENTAL SYSTEM IN THE PRE- AND POSTNATAL PERIODS OF DEVELOPMENT</article-title></title-group><contrib-group><contrib contrib-type="author"><name name-style="western"><surname>Krasnikova</surname><given-names>O. P</given-names></name><bio></bio><email>-</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Kuralesina</surname><given-names>V. P</given-names></name><bio></bio><email>-</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Vusataya</surname><given-names>E. V</given-names></name><bio></bio><email>-</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Abrosimova</surname><given-names>O. N</given-names></name><bio></bio><email>-</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Nigamova</surname><given-names>K. I</given-names></name><bio></bio><email>-</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Dremalov</surname><given-names>B. M</given-names></name><bio></bio><email>-</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Sagitdinova</surname><given-names>T. N</given-names></name><bio></bio><email>-</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff id="aff-1"></aff><pub-date date-type="epub" iso-8601-date="2021-12-15" publication-format="electronic"><day>15</day><month>12</month><year>2021</year></pub-date><volume>24</volume><issue>3</issue><fpage>38</fpage><lpage>42</lpage><history><pub-date date-type="received" iso-8601-date="2022-07-04"><day>04</day><month>07</month><year>2022</year></pub-date></history><permissions><copyright-statement>Copyright © 2021, Applied Information Aspects of Medicine (Prikladnye informacionnye aspekty mediciny)</copyright-statement><copyright-year>2021</copyright-year></permissions><abstract>We provide our own data on the results of studying the prevalence of early tooth decay in children living in the cities of Stary Oskol and Voronezh. The nature of the child's nutrition, the duration of use of the teat bottle, pacifiers, and the peculiarities of environmental living conditions were assessed. The most common form of early caries has been found to be "bottle caries." At the same time, the canines and second molars of the upper and lower jaws are less affected than the first molars due to a later eruption. The percentage of affected first molars was 57%, while the second milk molars was 24%. It is noted that the front teeth of the lower jaw are not affected. A significant contribution belongs to sugars burned in crumbs for artificial feeding. When breastfed, lactose contained in the mother's milk has cariogenic properties, which is associated with its cleavage in the oral cavity by saliva enzymes. A detailed study of the contribution of possible etiological factors to the development of dental abnormalities in the pre- and postnatal periods is critical for the development of preventive measures for each category of pediatric patients.</abstract><kwd-group xml:lang="en"><kwd>pre- and postnatal period</kwd><kwd>early caries</kwd><kwd>"bottle caries</kwd><kwd>" preventive measures</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>пре- и постнатальный период</kwd><kwd>ранний кариес</kwd><kwd>«бутылочный кариес»</kwd><kwd>профилактические мероприятия</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Бородина, К. М. Анализ изменений кислотно-щелочного баланса полости рта в различные сроки беременности / К. М. Бородина // Региональный вестник. - 2019. - № 16(31). - С. 15-16.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Гарина, И. К. 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