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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" article-type="research-article" dtd-version="1.1d1" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher">Applied Information Aspects of Medicine (Prikladnye informacionnye aspekty mediciny)</journal-id><journal-title-group><journal-title>Applied Information Aspects of Medicine (Prikladnye informacionnye aspekty mediciny)</journal-title></journal-title-group><issn publication-format="electronic">2070-9277</issn><publisher><publisher-name>Voronezh State Medical University named after N.N. Burdenko - The State Budgetary Institution of Higher Professional Education «Voronezh State Medical University named after N.N. Burdenko» of the Ministry of Public Health of the Russian</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">6804</article-id><article-id pub-id-type="doi">10.18499/2070-9277-2021-24-1-68-74</article-id><article-categories><subj-group subj-group-type="heading"><subject>Original Article</subject></subj-group></article-categories><title-group><article-title>PSYCHO-EMOTIONAL FACTOR IN PATHOGENESIS OF SEVERE FORMS OF RED FLAT DEPRIVATION OF ORAL MUCOSA AND RED LIP BORDER</article-title></title-group><contrib-group><contrib contrib-type="author"><name name-style="western"><surname>Serikova</surname><given-names>O. V</given-names></name><bio></bio><email>-</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Shumilovich</surname><given-names>B. R</given-names></name><bio></bio><email>-</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff id="aff-1"></aff><pub-date date-type="epub" iso-8601-date="2021-05-13" publication-format="electronic"><day>13</day><month>05</month><year>2021</year></pub-date><volume>24</volume><issue>1</issue><fpage>68</fpage><lpage>74</lpage><history><pub-date date-type="received" iso-8601-date="2021-05-13"><day>13</day><month>05</month><year>2021</year></pub-date></history><permissions><copyright-statement>Copyright © 2021, Прикладные информационные аспекты медицины</copyright-statement><copyright-year>2021</copyright-year></permissions><abstract>Clinical features of the course of red flat deprivation (CPL) localized on the mucous membrane of the oral cavity are characterized by a chronic course, high resistance to therapy, and the possibility of transition to malignant forms. CPL is a visible cosmetic drawback, the probability of transition to malignant forms leads to the development of anxiety, defensiveness, social maladaptation in patients. The aim of the study is to study the psychoemotional state of patients with severe forms of CPL, to develop schemes for optimizing therapy regimens. Severe forms of CPL have been found to be characterized by a progressive increase in anxiety rates. Evaluation of the psychoemotional factor in such patients is necessary, in order to correct the increased level of anxiety, it is advisable to prescribe psychotropic (sedative) pharmacological drugs as part of integrated therapy.</abstract><kwd-group xml:lang="en"><kwd>red flat lichen</kwd><kwd>oral mucosa</kwd><kwd>psychoemotional factor</kwd><kwd>anxiety</kwd><kwd>comprehensive therapy</kwd><kwd>psychotropic, sedatives</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>красный плоский лишай</kwd><kwd>слизистая оболочка ротовой полости</kwd><kwd>психоэмоциональный фактор</kwd><kwd>тревожность</kwd><kwd>комплексная терапия</kwd><kwd>психотропные, седативные препараты</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>1. Аллик Е.Л. Совершенствование лечения различных форм плоского лишая слизистой оболочки полости рта с учётом психологического статуса больных : автореф. дис.. канд. мед. наук / Е.Л. 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