Applied Information Aspects of Medicine (Prikladnye informacionnye aspekty mediciny)Applied Information Aspects of Medicine (Prikladnye informacionnye aspekty mediciny)2070-9277Voronezh State Medical University named after N.N. Burdenko - The State Budgetary Institution of Higher Professional Education «Voronezh State Medical University named after N.N. Burdenko» of the Ministry of Public Health of the Russian674210.18499/2070-9277-2019-22-3-54-59Original ArticleANALYSIS OF THE RATIONALITY OF PURPOSE OF MEDICINES OF NON-SPECIFIC PHARMACOTHERAPY BY PATIENTS WITH TUBERCULOSIS IN A HOSPITAL BASED ON DATA OF EVIDUAL MEDICINEArapbaevaD. A-TilekeevaU. M-Kyrgyz State Medical Academy15122019223545903042021Copyright © 2019, Прикладные информационные аспекты медицины2019The article analyzes the rationality of the use of drugs pathogenetic and symptomatic therapy in patients with newly diagnosed pulmonary tuberculosis, on the basis of evidence-based medicine. Revealed non-compliance with WHO indicators for proper prescription of drugs, a high level of polypharmacy of drugs of non-specific pharmacotherapy, against the background of etiotropic treatment with 4-5 antituberculosis drugs. The findings indicate low adherence to the clinical guidelines for organizing tuberculosis control in the Kyrgyz Republic and WHO recommendations for the prevention and treatment of isoniazid-induced hepatitis, the dosage regimen and the route of administration for pyridoxine hydrochloride. In actual clinical practice, a significant portion of tuberculosis patients receive non-targeted therapeutic drugs with unproven efficacy, which have no indication for use for this category of patients.newly diagnosed pulmonary tuberculosisrational use of drugspathogenetic and symptomatic drugsanti-tuberculosis drugsWHO indicatorsevidence-based medicineвпервые выявленный туберкулез легкихрациональное использование лекарственных средствлекарственные средства патогенетической и симптоматической терапиипротивотуберкулезные препаратыиндикаторы ВОЗдоказательная медицина1.Доклад о глобальной борьбе с туберкулезом. ВОЗ, 2017. - Режим доступа : Http://www.who.int/tb/publications/global_report/gtbr2017_executive_summary_ru.pdf?ua=1.2.Кадыров А.А. Эпидемиологическая ситуация по ТБ в Кыргызской Республике в 2012-2016 годах. / А.А. Кадыров // Наука, новые технологии и инновации Кыргызстана. - 2017. - №8. - С.3-7.3.Guidelines for the treatment of drug-susceptible tuberculosis and patient care, 2017 updat : WHO: HTM/TB/2017.054.Treatment of tuberculosis: guidelines - 4-ed.// World Health Organization, 2010: WHO/HTM/TB/2009.420.5.Сычев Д.А. Полипрагмазия в клинической практике: проблема и решения. учебное пособие / Д.А. Сычев. - Санкт-Петербург, 2016. - 224 с.6.Всемирная организация здравоохранения. Шестьдесят вторая сессия всемирной ассамблеи здравоохранения. Рациональное использование лекарственных средств (резолюция WHA60/16). -Женева, 2009. -6с. Серия: технических докладов ВОЗ. -№ 950.7.Тилекеева У.М. Анализ и пути оптимизации использования противотуберкулезных средств в Кыргызской Республике : автореф. дис…. д-ра мед. наук / У.М. Тилекеева.- Бишкек, 2007. - 42 c.8.The effect of multi-vitamin/mineral supplementation on mortality during treatment of pulmonary tuberculosis: a randomized two-by-two factorial trial in Mwanza, Tanzania / N.Range N.[ et al.] // British Journal of Nutrition. - 2006. - Vol. 95(4). - З.762-70.9.Nutritional supplements for people being treated for active tuberculosis / D. Sinclair[ et al. ]//Cochrane Database of Systematic Reviews. - 2011,. -Issue 11 - - CD006086.