Applied Information Aspects of Medicine (Prikladnye informacionnye aspekty mediciny)Applied Information Aspects of Medicine (Prikladnye informacionnye aspekty mediciny)2070-9277Voronezh State Medical University named after N.N. Burdenko - The State Budgetary Institution of Higher Professional Education «Voronezh State Medical University named after N.N. Burdenko» of the Ministry of Public Health of the Russian592510.18499/2070-9277-2020-23-2-36-42Original ArticleDIFFERENTIAL DIAGNOSIS OF PRIMARY THE LOSS OF THE MINERAL COMPONENT OF TOOTH ENAMEL USING A CONE-BEAM COMPUTER TOMOGRAPHYIppolitovYu A-GavrishA V-RostovtsevV V-MahmoudiA A-GlushenkovaO A-Voronezh State medical University22122020232364208092020Copyright © 2020, Прикладные информационные аспекты медицины2020Clinical differential diagnosis of primary hypomineralization and demineralization is a complex task, which fundamentally determines the tactics of further treatment of both childrens and adults. It is possible to establish exact quantitative criteria for the differential diagnosis of these conditions using CT densitometry. Native enamel without pathological changes has microhardness values in the range from 2800 to 4000 HU (Hausfields). Research have shown that with primary congenital hypomineralization of permanent teeth, these values are reduced to 1600-2000 HU, with subsurface demineralization - 1500-2600 HU with a decrease in hardness of more than 30% in the layers lying under the preserved enamel area without changing the thickness of the enamel in the area equator tooth. When surface demineralization values lie in the region from 1600 to 2900 HU, but there is a thinning of the enamel layer of less than 1 mm in the equatorial region of the tooth. The derived patterns make it possible to more reliably and confidently talk about the genesis of the identified pathological changes, and therefore - to choose the most optimal way to treat these conditions.personalized diagnosticsdental cariesdemineralizationhypomineralizationCT-densitometrynon-carious dental lesionsперсонифицированная диагностикакариес зубадеминерализациягипоминерализацияКТ-денситометриянекариозные поражения зубов1.Детская терапевтическая стоматология. Национальное руководство/под ред.В.К.Леонтьева,Л.П.Кисельниковой.- М.: ГЭОТАР-Медиа,2010.-896с.Серия «Национальные руководства»2.Терапевтическая стоматология: Учебник/Под ред. Ю.М. Максимовского.- М: Медицина, 2002.-640 с. ил.( Учеб.лит. Для студентов мед.вузов).3.Analysis of bone mineral density and content in children with molar incisor hypomineralization using dual-energy X-ray absorptiometry scan: A pilot study. Rahul M, Ashima G, Krishan G, Veenu S. Journal of the Indian Society of Pedodontics and Preventive Dentistry/ 2019 Jul-Sep;37(3):282-2854.Craveia J., Rouas P., Carat T., Manton D.J., Boileau M.J., Garot E. Knowledge and management of first permanent molars with enamel hypomineralization among dentists and orthodontists. The Journal of clinical pediatric dentistry. 2020;44(1):20-27. doi: 10.17796/1053-4625-44.1.45.Drummond В.К. Planningand Care for Children and Adolescents with Dental Enamel Defects: Etiology, ResearchandContemporaryManagement / B.K.Drummond, N.Kilpatrick. -Springer-VerlagBerlinHeidelberg, 2015. -175 p6.Epidemiology study of idiopathicenamelhypomineralizationinpermanentteethofSwedishchildren/G.Koch, A-LHallonsten, N. Ludvigsson et al.//Community Dent Oral Epidemiology.-1987.- Vol.15- P.279-2857.Interactions with the aquaporin 5 gene increase the susceptibility to molar-incisor hypomineralization. Pang L, Li X, Wang K, Tao Y, Cui T, Xu Q, Lin H. Archives of oral biology/ 2019 Dec 23;111:1046378.Kreulen C.M., Van 't Spijker A., Rodriguez J.M., Bronkhorst E.M. Systematic review of the prevalence of tooth wear in children and adolescents. Caries research. 2018;44(2):151-9. doi: 10.1159/000308567.9.Nor N.A.M., Chadwick B.L., Farnell D., Chestnutt I.G. The prevalence of enamel and dentine caries lesions and their determinant factors among children living in fluoridated and non-fluoridated areas. Community dental health. 2019 Aug 29;36(3):229-236. doi: 10.1922/CDH_4522Nor08.10.Patrick S., Birur N.P., Gurushanth K., Raghavan A.S., Gurudath S. Comparison of gray values of cone-beam computed tomography with hounsfield units of multislice computed tomography: An in vitro study. Indian J Dent Res. 2017 Jan-Feb;28(1):66-70.11.WeerheijmK.LMolarincisorhypomineralization(MIH)/ K.LWeerheijm//Eur.J. Paediatr.Dent.- 2003.-Vol.3.-P.115-12012.Zhao D., Dong B., Yu D., Ren Q., Sun Y. The prevalence of molar incisor hypomineralization: evidence from 70 studies. International journal of paediatric dentistry / the British Paedodontic Society and the International Association of Dentistry for Children. 2018 Mar;28(2):170-179. doi: 10.1111/ipd.12323. 9.