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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" article-type="research-article" dtd-version="1.1d1" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher">Applied Information Aspects of Medicine (Prikladnye informacionnye aspekty mediciny)</journal-id><journal-title-group><journal-title>Applied Information Aspects of Medicine (Prikladnye informacionnye aspekty mediciny)</journal-title></journal-title-group><issn publication-format="electronic">2070-9277</issn><publisher><publisher-name>Voronezh State Medical University named after N.N. Burdenko - The State Budgetary Institution of Higher Professional Education «Voronezh State Medical University named after N.N. Burdenko» of the Ministry of Public Health of the Russian</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">1879</article-id><article-id pub-id-type="doi">10.18499/2070-9277-2016-19-1-133-138</article-id><article-categories><subj-group subj-group-type="heading"><subject>Original Article</subject></subj-group></article-categories><title-group><article-title>A CIRCADIAN RHYTHM OF BLOOD PRESSURE IN PATIENTS WITH ESSENTIAL HYPERTENSION AND HYPERURICEMIA</article-title></title-group><contrib-group><contrib contrib-type="author"><name name-style="western"><surname>Fedoryako</surname><given-names>E V</given-names></name><bio></bio><email>-</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Provorotov</surname><given-names>V M</given-names></name><bio></bio><email>-</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff id="aff-1"></aff><aff id="aff-2">Voronezh State Medical University</aff><pub-date date-type="epub" iso-8601-date="2016-12-15" publication-format="electronic"><day>15</day><month>12</month><year>2016</year></pub-date><volume>19</volume><issue>1</issue><fpage>133</fpage><lpage>138</lpage><history><pub-date date-type="received" iso-8601-date="2020-04-24"><day>24</day><month>04</month><year>2020</year></pub-date></history><permissions><copyright-statement>Copyright © 2016, Прикладные информационные аспекты медицины</copyright-statement><copyright-year>2016</copyright-year></permissions><abstract>Several recent studies indicate that hyperuricemia may be an independent predictor of cardiovascular events in hypertensive patients. The purpose of research - to study the relationship of serum uric acid level with the options daily profile of blood pressure in hypertensive patients. Results: the combination of hypertension and asymptomatic GU revealed pathological changes in blood pressure regulation, the inversion of the circadian rhythm of blood pressure, increase in the time of the morning rise of systolic blood pressure These changes contribute to an increase in the load on the target organs and the development of changes in them (hypertrophy of the left heart).</abstract><kwd-group xml:lang="ru"><kwd>артериальная гипертензия</kwd><kwd>гиперурикемия</kwd><kwd>суточное мониторирование АД</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Panoulas VF, Milionis HJ, Douglas KMJ, Nightingale P, Kita MD, Klocke R, и др. Association of serum uric acid with cardiovascular disease in rheumatoid arthritis. Rheumatology (Oxford) [Интернет]. сентябрь 2007 г.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Веснина ЖВ, Арсеньева ЮА. Кардиоренальный синдром: современные взгляды на проблему взаимосвязи заболеваний почек и сердечно-сосудистой системы. Клиническая медицина [Интернет]. ОАО «Издательство «Медицина»; 2012 г.</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Zhang W, Doherty M, Pascual E, Bardin T, Barskova V, Conaghan P, и др. EULAR evidence based recommendations for gout. Part I: Diagnosis. Report of a task force of the Standing Committee for International Clinical Studies Including Therapeutics (ESCISIT). Ann Rheum Dis [Интернет]. октябрь 2006 г.</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>Johnson RJ, Kang D-H, Feig D, Kivlighn S, Kanellis J, Watanabe S, идр. Is there a pathogenetic role for uric acid in hypertension and cardiovascular and renal disease? Hypertension [Интернет]. июнь 2003 г.</mixed-citation></ref></ref-list></back></article>
