Applied Information Aspects of Medicine (Prikladnye informacionnye aspekty mediciny)

2070-9277

Voronezh State Medical University named after N.N. Burdenko - The State Budgetary Institution of Higher Professional Education «Voronezh State Medical University named after N.N. Burdenko» of the Ministry of Public Health of the Russian

1740

10.18499/2070-9277-2015-18-1-43-48

Original Article

EFFECT OF PRENATAL PASSIVE SMOKING FOR PATTERN OF ELECTRICAL RESPIRATORY DRIVE OF NEWBORNS RATS (IN VITRO)

Bolychevsky

S E

singlsb@mail.ruZinchenko

E A

physorgma@gmail.comMiroshnichenko

I V

miv_2000@mail.ru

Orenburg State Medical University

15052015

1814348

24042020

2015

It is now established that passive smoking during pregnancy increases the frequency and duration of slip-apnea in her baby. The aim of the study was to investigate the features of the functioning of the central mechanism for the generation of respiratory activity in neonatal rats who underwent in utero effects of passive smoking. The study was performed on the brain stem (BS) of newborn rats (n = 107) under conditions in vitro. Modeling of passive smoking was carried out by fumigation cigarette smoke females from 1 to 20 days of gestation. In BS of newborn rats undergoing prenatal passive smoking duration values respiratory cycle, amplitude and duration of the inspiratory discharge were significantly lower relative to the control data. Thus was established the influence of prenatal smoking on function of the respiratory center of newborn rats.

in vitro

новорожденные крысыдыхательный центрпассивное курениебульбоспинальный препарат

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