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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" article-type="research-article" dtd-version="1.1d1" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher">Applied Information Aspects of Medicine (Prikladnye informacionnye aspekty mediciny)</journal-id><journal-title-group><journal-title>Applied Information Aspects of Medicine (Prikladnye informacionnye aspekty mediciny)</journal-title></journal-title-group><issn publication-format="electronic">2070-9277</issn><publisher><publisher-name>Voronezh State Medical University named after N.N. Burdenko - The State Budgetary Institution of Higher Professional Education «Voronezh State Medical University named after N.N. Burdenko» of the Ministry of Public Health of the Russian</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">1679</article-id><article-id pub-id-type="doi">10.18499/2070-9277-2014-17-1-52-55</article-id><article-categories><subj-group subj-group-type="heading"><subject>Conference Proceedings</subject></subj-group></article-categories><title-group><article-title>EXPERIENCE WITH THE USE AGOMELATINE HYPERTENSIVE PATIENTS HIGH RISK</article-title></title-group><contrib-group><contrib contrib-type="author"><name name-style="western"><surname>Gosteva</surname><given-names>E V</given-names></name><bio></bio><email>-</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Vasileva</surname><given-names>L V</given-names></name><bio></bio><email>-</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff id="aff-1">Voronezh N.N. Burdenko State Medical Academy</aff><pub-date date-type="epub" iso-8601-date="2014-12-15" publication-format="electronic"><day>15</day><month>12</month><year>2014</year></pub-date><volume>17</volume><issue>1</issue><fpage>52</fpage><lpage>55</lpage><history><pub-date date-type="received" iso-8601-date="2020-04-24"><day>24</day><month>04</month><year>2020</year></pub-date></history><permissions><copyright-statement>Copyright © 2014, Прикладные информационные аспекты медицины</copyright-statement><copyright-year>2014</copyright-year></permissions><abstract>There are literature date about depression and anxiety as risk factors of atherosclerotic genesis of cardiovascular diseases. Their prophylaxis and correction is an necessary part of prophylaxis of these diseases. The application of valdoxan (agomelatin) for treatment of patients with arterial hypertension of high risk has observed.</abstract><kwd-group xml:lang="ru"><kwd>артериальная гипертензия</kwd><kwd>ишемическая болезнь сердца</kwd><kwd>депрессия</kwd><kwd>вальдоксан</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Оганов Р.Г.Депрессивные расстройства в общесоматической практике по данным исследования КОМПАС: взгляд кардиолога. /Р.Г.Оганов, В.И.Погосова,С.А.Шальнова и др.// Кардиология 2005.- №8.- С.38-44</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Кардиоваскулярная профилактика. Национальные клинические рекомендации. Всероссийское научное общество кардиологов, 2011. Сборник. Под ред. Р.Г.Оганова. 4-е издание. М: «Силиция-Полиграф» 2011. - С.17-112.</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Perk J., De Backer G., Gohlke H. et al. European Guidelines on cardiovascular disease prevention in clinical practice (version 2012). Eur Heart J 2012. -№ 33. - Р.1635- 1701.</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>Олье Ж.П., Каспер 3. Эффективность Вальдоксана (агомелатина), агониста МТ1/МТ2- рецепторов и антагониста 5НТ2С-рецепторов при большом депрессивном расстройстве. Рос. психиатр, журн. 2009.- №2. - С. 85-95.</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>Loo H, Hale A, D'haenen H. Determination of the dose of agomelatine, a melatoninergic agonist and selective 5HT-antagonist, in the treatment of mayor depressive disorder: a placebo-controlled dose range study. Int Clin Psychopharmacol. 2002.- №17. - Р. 239-47.</mixed-citation></ref></ref-list></back></article>
