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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" article-type="research-article" dtd-version="1.1d1" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher">Applied Information Aspects of Medicine (Prikladnye informacionnye aspekty mediciny)</journal-id><journal-title-group><journal-title>Applied Information Aspects of Medicine (Prikladnye informacionnye aspekty mediciny)</journal-title></journal-title-group><issn publication-format="electronic">2070-9277</issn><publisher><publisher-name>Voronezh State Medical University named after N.N. Burdenko - The State Budgetary Institution of Higher Professional Education «Voronezh State Medical University named after N.N. Burdenko» of the Ministry of Public Health of the Russian</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">1353</article-id><article-id pub-id-type="doi">10.18499/2070-9277-2003-6-1-11-14</article-id><article-categories><subj-group subj-group-type="heading"><subject>Original Article</subject></subj-group></article-categories><title-group><article-title>PREDICTION DEVELOPMENT AND OPTIMIZATION OF THERAPEUTIC EFFECTS IN PATIENTS WITH ATHEROSCLEROSIS USING THE PRINCIPLES SYSTEMATIC APPROACH AND MATHEMATICAL MODELING</article-title></title-group><contrib-group><contrib contrib-type="author"><name name-style="western"><surname>AP</surname><given-names>Babkin P</given-names></name><bio></bio><email>-</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff id="aff-1">Voronej state medical academy</aff><pub-date date-type="epub" iso-8601-date="2003-12-15" publication-format="electronic"><day>15</day><month>12</month><year>2003</year></pub-date><volume>6</volume><issue>1</issue><fpage>11</fpage><lpage>14</lpage><history><pub-date date-type="received" iso-8601-date="2020-04-22"><day>22</day><month>04</month><year>2020</year></pub-date></history><permissions><copyright-statement>Copyright © 2003, Прикладные информационные аспекты медицины</copyright-statement><copyright-year>2003</copyright-year></permissions><abstract>He study involved 377 patients with different localization of atherosclerosis: coronary arteries (carotid arteries - 201 lower limb arteries - 182 people), which carried out the verification of atherosclerotic lesion angiographic and ultrasound methods, system analysis of atherosclerotic process various localization based on regression analysis and neural network modeling algorithm is proposed choice of a rational plan of remedial measures on the basis of an optimization model for the combination of the most effective drugs based on their compatibility and restrictions on the total cost of treatment., whose integration within software system provides an opportunity to support the activity of the doctor when choosing a rational treatment plan taking into account the individual characteristics of the patients.</abstract><kwd-group xml:lang="ru"><kwd>Атеросклероз</kwd><kwd>системный анализ</kwd><kwd>моделирование</kwd><kwd>верификация атеросклеротического поражения</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Аронов Д.М. Взаимосвязь показателей холестеринтранспорнтной системы крови с клиническими проявлениями и выраженностью коронарного атеросклероза / Аронов Д.М., Жидко Н.И., Перова Н.В. и др. // Кардиология, 1995. № 11. С. 35-45.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Бабкин А.П., Исаков П.Н., Чопоров О.Н. Моделирование развития атеросклероза на основе нейросетей // Окружающая среда и здоровье человека: Сб. научн. и практ. работ, Воронеж Старый Оскол, 2000. С.226-231.</mixed-citation></ref></ref-list></back></article>
