Applied Information Aspects of Medicine (Prikladnye informacionnye aspekty mediciny)Applied Information Aspects of Medicine (Prikladnye informacionnye aspekty mediciny)2070-9277Voronezh State Medical University named after N.N. Burdenko - The State Budgetary Institution of Higher Professional Education «Voronezh State Medical University named after N.N. Burdenko» of the Ministry of Public Health of the Russian131510.18499/2070-9277-2002-5-1-2-59-64Original ArticleExamination of vegetative status in patients with acquired heart diseaseMinakovE V-FursovaЕ А-Voronezh State Medical AcademyVoronezh Regional Clinical Hospital No11512200251-2596422042020Copyright © 2002, Прикладные информационные аспекты медицины2002Clinical course of cardiac insufficiency is determined by activation of neurohumoral systems. Neurohumoral activation leads to vegetative imbalance. Vegetative disorders play major role in cardio-vascular system diseases. The aim of the research is to study the indices of heart rate variability in patients with chronic cardiac insufficiency. 95 patients with chronic cardiac insufficiency were examined simultaneously with a control group of 20 healthy people without any cardio-vascular pathology. Patients with rheumatic heart diseases (associated aortic and combined mitral-aortic defects) were included into the research. Circulatory deficiency - I-II, functional class I - Ш. Vegetative status was assessed with the use of computer hardware complex “VARICARD”, evaluating 5 one-minute intervals (while conducting active tilt-test); initially - after the performance of traditional medicament treatment and later - in one month after the surgical correction of a defect. Baroreceptor sensitivity was increased after surgery. High indices of initial activity of parasympathetic nervous system prove that it was stimulated by drugs, used in the long-term treatment of chronic cardiac insufficiency (inhibitors of angiotensin transforming ferment, β-blockers, cardiac glycosides) and that cardiac insufficiency sickness rate is comparatively low.нейрогуиоральные системысердечная недостаточностьрецепторы1.1. Михайлов В.М. Опыт практического применения /В.М. Михайлов // Вариабельность ритма сердца. 2000. -200 с.2.2. Дземешкевич С. JI. Антикоагулянтная терапия у паци-ентов с клапанными пороками сердца / СЛ. Дземешкевич, Е.П. Панченко //Русский Медицинский Журнал. 2001. Т. 9, № 10. - С. 427 - 429.3.3. Бабунц И.В. Азбука анализа вариабельности сердечного ритма /И.В. Бабунц, Э.М. Мириджанян, Ю.А. Машаех. Ставрополь, 2002. - 112 с.4.4. Черепенин Л.П. Программа обследования больных с изолированными митральными пороками сердца для оценки степени легочной гипертензии / Л.П. Черепенин, Е.В. Привалова, А.С. Иванов //Клин, медицина. 2000. - № 3. - С. 28-32.5.5. Cohn J.N. Effect of the angiotensin receptor blocker valsartan on morbidity and mortality in heart failure: The Valsartan Heart Failure Trial (Val-HeFT) // 2nd Intern. Forum on Angiotensin II Receptor Antagonism. Monte-Carlo, 2001.-Abstr.-P. 13.