Applied Information Aspects of Medicine (Prikladnye informacionnye aspekty mediciny)Applied Information Aspects of Medicine (Prikladnye informacionnye aspekty mediciny)2070-9277Voronezh State Medical University named after N.N. Burdenko - The State Budgetary Institution of Higher Professional Education «Voronezh State Medical University named after N.N. Burdenko» of the Ministry of Public Health of the Russian1158010.18499/2070-9277-2026-29-1-165-175Diatom algae of the genus skeletonema: chemical composition and prospects for use in medical practiceMikhailovaElena<p>PhD, Associate Professor of the Department of Pharmaceutical Business Organization, Clinical Pharmacy, and Pharmacognosy</p>milenok2007@mail.ruPopovSergei<p>Doctor of Medical Sciences, Head of the Department of Pharmaceutical Business Organization, Clinical Pharmacy, and Pharmacists</p>popov-endo@mail.ruBredikhinaTatyana<p>PhD, Associate Professor at the Department of Pharmaceutical Business Organization, Clinical Pharmacy, and Pharmacognosy</p>bredichina-tat@yandex.ruN.N. Burdenko Voronezh State Medical University of the Russian Ministry of Health0704202629116017002042026Copyright © 2026, Applied Information Aspects of Medicine (Prikladnye informacionnye aspekty mediciny)2026<p>The wide range of biologically active compounds of diatoms of the genus Skeletonema makes them a promising object for the pharmaceutical industry. In connection with the above, the purpose of this work was to study the chemical composition and related pharmacological effects of representatives of the genus Skeletonema based on the analysis and systematization of data obtained from domestic and foreign literary sources. Chemical analysis revealed a significant amount of polyunsaturated fatty acids, saturated fatty acids, as well as fatty acid esters and amides, monoacylglycerols, oxylipins, glycosphingolipids, free and conjugated forms of sterols, polysaccharides and monosaccharides, phenolic compounds, vitamins and other compounds. The pigment composition contains chlorophyll , fucoxanthin, diadinoxanthin, astaxanthin and -carotene. A high concentration of pheophorbide was detected. Stress conditions, such as light, temperature, salt stress, change in concentration of biogenic elements, can be used to intensify biosynthesis of target biologically active substances.</p>
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