Applied Information Aspects of Medicine (Prikladnye informacionnye aspekty mediciny)

2070-9277

Voronezh State Medical University named after N.N. Burdenko - The State Budgetary Institution of Higher Professional Education «Voronezh State Medical University named after N.N. Burdenko» of the Ministry of Public Health of the Russian

10099

10.18499/2070-9277-2024-27-2-11-16

Original Article

Comparative characteristics of antibacterial pharmacotherapy in aseptic surgical interventions in the oral cavity

Kvashnin

Dmitry Viktorovich

Postgraduate student, Assistant of the Department of Surgical Dentistrystomdk@yandex.ruKharitonov

Dmitry Yurievich

MD, Professor, Director of the Institute of Dentistry, Head of the Department of Surgical Dentistrystomatolog@vrngmu.ruShcherbinin

Александр Sergeevich

PhD, Associate Professor of the Department of Surgical Dentistrystomat_okb@mail.ruKumirova

Olga Alexandrovna

PhD, Associate Professor of the Department of Surgical Dentistryfsvsmaburdenko@mail.ru

VSMU named after N.N. BurdenkoВГМУ им. Н.Н. Бурденко

28062024

2721116

05072024

2024

Incorrect administration of antibacterial drugs during aseptic surgical interventions in the oral cavity plays one of the leading roles in complications during outpatient admission in surgical dentistry. Uncontrolled use of antibiotics leads not only to inflammatory complications, but also complicates the further management of the surgical patient. When prescribing antibiotics in cases where there is no need for their appointment, the level of pathogenic flora increases, the phagocytic link of nonspecific immunity weakens, and the cytokine profile of the oral fluid decreases. In the future, there is a risk of infectious complications in the management of this patient, for example, in the case where it is necessary to remove retinated, dystopian third molars for orthodontic indications or install dental implants in included defects in different segments. To reduce the number of complications and a favorable course of the postoperative period, it is necessary to take into account such criteria of surgical intervention as: the volume and time of surgery, the presence of osteotomy, the age of the patient and the presence of concomitant pathology. The purpose of this study was a comparative analysis of clinical and laboratory parameters of the postoperative period of patients with aseptic surgical interventions using antibacterial pharmacotherapy and without the use of antibiotics. A comparative analysis of the phagocytic link of immunity and the cytokine profile of oral fluid in patients who underwent removal of the third molar according to orthodontic indications and installation of a single dental implant in a limited defect was performed. Based on the data obtained, it is proved that the use of antibacterial drugs is not advisable if surgery lasts less than 30 minutes, osteotomy is not used for tooth extraction, the patient is under 35 years old, and there is no concomitant pathology.

antibiotics, surgical dentistry, dental implantation, removal of retinated molars.

антибиотики, хирургическая стоматология, дентальная имплантация, удаление ретинированных моляров.

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