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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" article-type="research-article" dtd-version="1.1d1" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher">Applied Information Aspects of Medicine (Prikladnye informacionnye aspekty mediciny)</journal-id><journal-title-group><journal-title>Applied Information Aspects of Medicine (Prikladnye informacionnye aspekty mediciny)</journal-title></journal-title-group><issn publication-format="electronic">2070-9277</issn><publisher><publisher-name>Voronezh State Medical University named after N.N. Burdenko - The State Budgetary Institution of Higher Professional Education «Voronezh State Medical University named after N.N. Burdenko» of the Ministry of Public Health of the Russian</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">10098</article-id><article-id pub-id-type="doi">10.18499/2070-9277-2024-27-2-4-10</article-id><article-categories><subj-group subj-group-type="heading"><subject>Original Article</subject></subj-group></article-categories><title-group><article-title>Gingivitis against the background of the use of metal alloys in the oral cavity: the use of gels containing bacteriophages</article-title></title-group><contrib-group><contrib contrib-type="author"><name name-style="western"><surname>Ippolitov</surname><given-names>Yuri Alexeyevich</given-names></name><bio>&lt;p&gt;MD, Professor, Head of the Department of Pediatric Dentistry with Orthodontics&lt;/p&gt;</bio><email>dsvgma@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Uryadnikova</surname><given-names>Valeria Alexandrovna</given-names></name><bio>&lt;p&gt;Postgraduate student of the Department of Pediatric Dentistry with Orthodontics&lt;/p&gt;</bio><email>uryadnikova.96@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Mikhailova</surname><given-names>Svetlana Anatolievna</given-names></name><bio>&lt;p&gt;PhD, Associate Professor of the Department of Pediatric Dentistry with Orthodontics&lt;/p&gt;</bio><email>svetamih1367@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Ippolitov</surname><given-names>Ivan Yurievich</given-names></name><bio>&lt;p&gt;Candidate of Medical Sciences, Assistant of the Department of Orthopedic Dentistry&lt;/p&gt;</bio><email>ippolitoff87@bk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Alyoshina</surname><given-names>Elena Olegovna</given-names></name><bio>&lt;p&gt;PhD, Associate Professor of the Department of Pediatric Dentistry with Orthodontics&lt;/p&gt;</bio><email>aeo86@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Kuralesina</surname><given-names>Victoria Pavlovna</given-names></name><bio>&lt;p&gt;PhD, Associate Professor of the Department of Pediatric Dentistry with Orthodontics&lt;/p&gt;</bio><email>dsvgma@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Rusanova</surname><given-names>Tatyana Anatolievna</given-names></name><bio>&lt;p&gt;PhD, Associate Professor of the Department of Advanced Training of Highly qualified Personnel&lt;/p&gt;</bio><email>dsvgma@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>The womb</surname><given-names>Irina Igorevna</given-names></name><bio>&lt;p&gt;student&lt;/p&gt;</bio><email>utrobina10@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Kanovka</surname><given-names>Anna Romanovna</given-names></name><bio>&lt;p&gt;student&lt;/p&gt;</bio><email>anna.kanovka@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff id="aff-1">VSMU named after N.N. Burdenko</aff><pub-date date-type="epub" iso-8601-date="2024-06-28" publication-format="electronic"><day>28</day><month>06</month><year>2024</year></pub-date><volume>27</volume><issue>2</issue><fpage>4</fpage><lpage>10</lpage><history><pub-date date-type="received" iso-8601-date="2024-07-05"><day>05</day><month>07</month><year>2024</year></pub-date></history><permissions><copyright-statement>Copyright © 2024, Applied Information Aspects of Medicine (Prikladnye informacionnye aspekty mediciny)</copyright-statement><copyright-year>2024</copyright-year></permissions><abstract>&lt;p&gt;Gingivitis is one of the most common complications in patients undergoing orthodontic treatment. Since various types of alloys are used during orthodontic treatment, it becomes necessary to search for the relationship between the type of metal used, the degree of gum damage and an effective anti-inflammatory agent that does not cause dysbiosis of the oral cavity.&lt;/p&gt;&#13;
&lt;p&gt;The object of the study is patients undergoing orthodontic treatment aged 25 to 35 years without general somatic pathology. The patients were divided into 2 groups. In group A, orthodontic arches made of nickel-titanium alloy were used. In group B, medical steel arcs. In subgroups A1, B1, the antiseptic chlorhexidine bigluconate 0.05% was used, and in subgroups A2 and B2, a gel with bacteriophages "Phagodent" was used.&lt;/p&gt;&#13;
&lt;p&gt;Research methods: survey, examination, study of medical documentation, application of indices for determining plaque Silness-Loe, PMA, perhydrol sample and Schiller-Pisarev.&lt;/p&gt;&#13;
&lt;p&gt;Examinations of patients were carried out on the 3rd, 6th, 9th, 12th days from the start of therapy. As a result of the study, it was found that the accumulation of plaque and the degree of gingival inflammation were higher in patients with arches made of nickel and titanium alloy than from medical steel due to their pronounced roughness and the presence of many retention areas of the oral cavity.&lt;/p&gt;&#13;
&lt;p&gt;As a result of the study, it was found that in patients who received complex treatment with the use of Phagodent gel, the inflammatory process in the gum was eliminated in subgroup B2 on day 9, and in subgroup A2 on day 12. Whereas in subgroup A1, the index indicators did not reach the norm, and in subgroup B 1, the index indicators returned to normal on day 12.&lt;/p&gt;</abstract><kwd-group xml:lang="en"><kwd>bacteriophage, gingivitis, orthodontic arches made of nickel-titanium alloy, orthodontic arches made of medical steel.</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>Гингивит - одно из самых распространенных осложнений у пациентов, находящихся на ортодонтическом лечении. Так как во время ортодонтического лечения применяются различные виды сплавов металлов, возникает необходимость поиска взаимосвязи вида используемого металла и степени поражение дёсен, а также эффективного противовоспалительного средства, не вызывающего дисбактериоза полости рта. &#13;
Объект исследования -  пациенты, находящиеся на ортодонтическом лечении в возрасте от 25 до 35 лет без общесоматической патологии. Пациенты были разделены на 2 группы. В группе А использовались ортодонтические дуги из сплава никеля с титаном. В группе В дуги из медицинской стали. В подгруппах А1,В1 применялся антисептик хлоргексидина биглюконат 0,05%, а в подгруппах А2 и В2 был применён гель с бактериофагами «Фагодент». &#13;
Методы исследования: опрос, осмотр, изучение медицинской документации, применение индексов определения зубного налета Silness-Loe, РМА, пергидролевой пробы и Шиллера-Писарева.&#13;
Осмотры пациентов проводили на 3, 6, 9, 12 сутки от начала терапии. В результате исследования было констатировано, что скопление зубного налёта и степень воспаления десны было выше у пациентов с дугами из сплава никеля и титана, чем из медицинской стали по причине их выраженной шероховатости и наличия множества ретенционных участков полости рта. &#13;
В результате проведенного исследования было констатировано, что у пациентов получивших комплексное лечение с применением геля «Фагодент» воспалительный процесс в десне был ликвидирован в подгруппе В2 на 9 сутки, а в подгруппе А2 на 12 сутки. Тогда как в подгруппе А1 индексные показатели не достигли нормы, а в подгруппе В 1 индексные показатели пришли к норме на 12 сутки.</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>bacteriophage, gingivitis, orthodontic arches made of nickel-titanium alloy, orthodontic arches made of medical steel.</mixed-citation></ref></ref-list></back></article>
