IMMUNOLOGIC PROFILE AND CLINICAL VALUE OF THE APOPTOSIS OF IMMUNOCOMPETENT CELLS AT NEWBORNS WITH THE SERIOUS ASPHYXIA

N V Bugrym; Бугрым Н В; I I Logvinova; Логвинова И И; E L Krutskikh; Крутских Е Л; N I Ivanova; Иванова Н И; N V Bugrym; Bugrym N V; I I Logvinova; Logvinova I I; E L Krutsky; Krutsky E L; N I Ivanov; Ivanov N I

doi:10.18499/2070-9277-2009-0-12-122-132

IMMUNOLOGIC PROFILE AND CLINICAL VALUE OF THE APOPTOSIS OF IMMUNOCOMPETENT CELLS AT NEWBORNS WITH THE SERIOUS ASPHYXIA

Authors: Bugrym NV¹, Logvinova II¹, Krutskikh EL¹, Ivanova NI¹, Bugrym NV², Logvinova II², Krutsky EL², Ivanov NI²
Affiliations:
2. The Voronezh state medical academy of N.N.Burdenko
Issue: No 12 (2009)
Pages: 122-132
Section: Articles
URL: https://new.vestnik-surgery.com/index.php/2070-9277/article/view/5436
DOI: https://doi.org/10.18499/2070-9277-2009-0-12-122-132

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Abstract

The estimation of an apoptosis of immune cells and condition of cellular and humoral links of immune system at newborns transferred a serious asphyxia was spent. 47 full-term newborns for 1-2 days and for 4-5 days are surveyed. By results of a frequency analysis установленно, that children who have transferred a serious asphyxia, have raised indicators CD4, CD8, Cd95-apoptoza and lowered indicators CD19, CD56, ИАН at a birth in peripheric blood. In early neonatal adaptation, for 4-5 days had raised indicators CD3, CD4, Cd95-apoptoza, НСТ a MOF, and lowered indicators CD19, CD56, IgA, IgM, ИАН, that testifies to failure of adaptatsionno-COMPENSATORY mechanisms of an organism and leads to depression of its protective function.

Keywords

an asphyxia, immunity, newborns

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IMMUNOLOGIC PROFILE AND CLINICAL VALUE OF THE APOPTOSIS OF IMMUNOCOMPETENT CELLS AT NEWBORNS WITH THE SERIOUS ASPHYXIA

Full Text

Abstract

Keywords

About the authors

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