No 61 (2015)

Articles
THE CLINICAL CASE OF COMBINATION OF AUTOIMMUNE HEPATITIS, PRIMARY BILIARY CIRRHOSIS AND ULCERATIVE COLITIS BY A 56 YEAR-OLD PATIENT
Chernuh T.M., Sviridova T.N., Alexeev N.Y., Sudakov O.V.
Abstract
The represented clinical case deals with the question of combined autoimmune disorders of the digestive system: autoimmune hepatitis, primary biliary cirrhosis and ulcerative colitis. The descriptive using of fecal calprotectin biomarker is shown for the diagnostics of inflammatory bowel disease. The expediency of examination of patients with inflammatory bowel disease is substantiated for detection of autoimmune disorders of the liver and patients with autoimmune disorders of the liver for elimination of presence of inflammatory bowel disease.
Научно-медицинский вестник Центрального Черноземья. 2015;(61):3-10
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EXPERIENCE OF TEACHERSCHAIRS OF HOSPITAL THERAPY AND ENDOCRINOLOGY OF VORONEZH STATE MEDICAL UNIVERSITY THE CENTER OF PREVENTION OF WARM AND VASCULAR DISEASES OF VORONEZH
Chernykh T.M., Fursov E.A.
Abstract
Meaningful form of organizational-methodical work of medical institutions of higher education teachers is to conduct lectures and seminars on actual problems of medical prevention among the population. Keywords: cardiovascular diseases, modifiable risk factors, information lectures for teachers of medical institutions of higher education
Научно-медицинский вестник Центрального Черноземья. 2015;(61):11-13
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MEDICO-SOCIAL CHARACTERISTICS OF WOMEN OF THE VORONEZH REGION WITH CANCER
Kosolapov V.P., Sych G.V., Sych A.V.
Abstract
The problem of morbidity, disability and mortality of women population due to malignant neoplasms is one of the most actual in modern medicine. Concern and attention to cancer due to stable growth worldwide incidence that in the foreseeable future will continue to increase due to a variety of subjective and objective causes aging of the population, environmental, economic and other factors. In 2014, the first time in Russia revealed more than 567 thousand cancer patients, died from cancer patients 289 thousand, which is 15,4% in the total mortality (the second reason after cardiovascular diseases). In the structure of mortality from malignant tumors more than 30% occupied by people under the age of 60 years, indicating that the extremely high social importance of early diagnosis, prevention and treatment of cancer. The fact that the upward trend in the incidence of cancer has long been maintained, despite the obvious advances in the diagnosis and treatment of tumors, indirect evidence that crucial in cancer fight belongs to cancer prevention, including the study of the most relevant factors affecting the development of tumors. This paper presents the characteristics of the socio-hygienic characteristics of women with tumors.
Научно-медицинский вестник Центрального Черноземья. 2015;(61):14-19
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ROLE OF TUMOR NECROSIS FACTOR-α IN THE DEVELOPMENT OF OXIDATIVE STRESS AND INFLAMMATION
Tsvetikova L.N., Atyakshin D.A., Lobeeva N.V.
Abstract
The tumor necrosis factor - α (TNF-α) is involved in immune regulation, the development of inflammation and hemodynamic disturbances in different human diseases, both infectious and non-infectious nature. TNF-α can induce apoptosis through activation of caspase-3, and through the activation of caspase-8, which leads to increased intracellular levels of reactive oxygen species and oxidative stress. Gene expression of antioxidants and cytokines (TNF-α, interleukin-6 (IL-6), IL-1, IL-8) and transcription factors (SIP, NF kappa β) increases by oxidative stress and affects to the immune system and inflammatory processes. TNF-α can be used in complex analysis to assess the extent of the inflammatory process in the dynamics and have important diagnostic value for the prediction and prevention of diseases.
Научно-медицинский вестник Центрального Черноземья. 2015;(61):20-23
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CLINIC CHRONIC OBSTRUCTIVE PULMONARY DISEASE AND ANEMIA, GENDER DIFFERENCES
Budnevsky A.V., Provotorov V.M., Ulyanova M.I., Shegida Y.V.
Abstract
Due to the wide prevalence of chronic obstructive pulmonary disease (COPD) direct and indirect costs due to disability and premature mortality are quite high and significantly increase the economic burden on the state budget. Recently, much attention is paid to the differences in COPD with systemic manifestations of it, including the anemic syndrome, and the study of quality of life of patients, male and female. The study gender-specific quality of life of patients will optimize the complex medical care to patients with COPD.
Научно-медицинский вестник Центрального Черноземья. 2015;(61):24-29
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DEVELOPMENT OF RURAL MEDICINE IN THE MODERN CONDITIONS IN THE TERRITORY OF THE VORONEZH REGION
Kosolapov V.P., Chubirko Y.M., Sych G.V., Chubirko I.E.
Abstract
The main directions of the organization of medical care to country people in the Voronezh region and the Russian Federation are considered. The factors influencing specifics of incidence of inhabitants of rural areas are explained, dynamics of the medical organizations providing medical care to country people is reflected, paths of development of rural medicine are offered.
Научно-медицинский вестник Центрального Черноземья. 2015;(61):30-34
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THE ORGANIZATION AND WORK OF THE COASTAL HOSPITAL DURING THE FIRST CAMPAIGN OF THE RUSSIAN NAVY IN 1757 IN THE SEVEN YEARS' WAR
Popov Y.M.
Abstract
One of the main events of the Seven Years' War is Russian fleet participation in the hostilities against Prussia. The large number of sick sailors on ships in the first campaign in 1757 forced the command to establish a coast hospital on the shore of the Gdansk Gulf for further treatment. This article is devoted to the peculiarities of this process.
Научно-медицинский вестник Центрального Черноземья. 2015;(61):35-39
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I.P. TARADIN AS a DOCTOR, MEDICINE HISTORIAN AND PHILOSOPHER (to 125 anniversary since birth)
Malikova A.A.
Abstract
The article is concerned with the historical ideas and activities of the first head the Department of Voronezh State Medical University I.P. Taradin and there is provided biographical information about him.
Научно-медицинский вестник Центрального Черноземья. 2015;(61):40-43
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MODERN LEVEL OF PALLIATIVE CARE, MEDICAL AND SOCIAL ASSISTANCE IN RUSSIA
Redkin A.N., Ivanova J.S., Manykovskaya O.V., Karpova V.G.
Abstract
Today there is a big problem of cancerous diseases among the population all over the world. Despite the fact that measures for active detection of cancer patients, achievement in diagnosis and treatment of malignant tumors are really good, cancerous diseases are one of the first places in the structure of mortality of the population. So in Russian Federation cancerous diseases are the second place after cardiovascular system. Besides the number of incurable patients has been increasing at last years. The aim of the literary review is to define the term "palliative care", find out some problems, give the documents about palliative care.
Научно-медицинский вестник Центрального Черноземья. 2015;(61):44-53
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CLINIC CHRONIC OBSTRUCTIVE PULMONARY DISEASE AND ANEMIA: GENDER DIFFERENCES
Budnevsky A.V., Provotorov V.M., Ulyanova M.I., Shegida Y.V.
Abstract
Anemia refers to the manifestations of systemic inflammation in chronic obstructive pulmonary disease (COPD) and a factor aggravating the disease. Gender aspects of the clinical manifestations of anemia and treatment strategy is practically not been studied, and that was the basis for the study. Revealed the influence of gender dimorphism is related anemia on clinical symptoms and quality of life of patients with COPD. Women received significantly greater inconsistency of the mental health than men, the physical parameters of health were violated in patients of both sexes equally.
Научно-медицинский вестник Центрального Черноземья. 2015;(61):54-61
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COMPARISON AND ANALYSIS METHODS OF PRESSURE ON THE TARGET GROUPS
Vaskina E.E.
Abstract
The research was conducted on patients having different diseases, in particular patients with isolated systolic hypertension (ISAH). The results of blood pressure readings measured by the oscillometric and Korotkov method, were significantly different. The program SPSS Statistics 17.0 summarizes the required data about the patients on the basis of the analysis of target groups by means of criterion Student.
Научно-медицинский вестник Центрального Черноземья. 2015;(61):62-66
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STUDY OF THE ADAPTIVE CAPABILITIES OF STUDENTS-ATHLETES
Gladskich N.A., Korotkova S.B., Fursova E.A.
Abstract
Sports development plays an important role in formation of the student as an individual. Permanent training process allows you to maintain good form the cardiovascular and respiratory system. Definition of adaptive capacity of an organism plays a role in the assessment not only of the State of the organism, but also allows you to monitor the training process. Reduce the physical load in a timely manner avoiding muscle fatigue effect, rationally to undertake remediation activities. All these measures allow to approach the competition in optimum physical condition. We built mathematical models of adaptive capacity of athletes engaged in light and heavy training, aimed at optimization of the preparation for a competition.
Научно-медицинский вестник Центрального Черноземья. 2015;(61):67-74
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CHILDREN AGE AND SEX DIFFERENCES OF BLOOD PRESSURE IN THE VORONEZH REGION
Zhdanova O.A., Sitnikova V.P.
Abstract
The article presents the results of statistical analysis of the blood pressure of 1124 boys and 1185 girls 7-16 years old living in the Voronezh region in 2011-2014. Systolic blood pressure of the boys prevailed over systolic blood pressure values of the girls at all ages groups. The minimal differences were at the age of 10 years old, maximal - at 15 and 16 years old (р0,005). The average measurements of diastolic blood pressure of girls at 8-10 years old and 13 were higher but at the age of 14- lower than the same numbers at boys group. It was discovered a small decrease in the measures of diastolic blood pressure at 15-16 years old girls group in comparison with the younger girls group.
Научно-медицинский вестник Центрального Черноземья. 2015;(61):75-79
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ALIMENTARNYE FACTORS In The Etiology Of MALIGNANT NEOPLASMS (on the example of the Oryol region)
Saurina O.S.
Abstract
Cancer is a major cause of morbidity and mortality throughout the world - in 2012 year occurred about 14 million new cases and 8.2 million deaths associated with cancer. In developed countries, cancer is the second most among all causes of death after cardiovascular diseases. About one-third of cancer deaths are caused by 5 major risk factors that are associated with the behavior and diet, such as high body mass index, insufficient consumption of fruits and vegetables, physical inactivity, tobacco use and alcohol consumption.
Научно-медицинский вестник Центрального Черноземья. 2015;(61):80-85
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IMPROVING THE QUALITY OF LIFE OF PATIENTS SUFFERING FROM CHRONIC OBSTRUCTIVE PULMONARY DISEASE AND IN THE TREATMENT OF ANDROGENIC DEFICIT ANDRIOL
Provotorov V.M., Perveev I.M., Titova L.A.
Abstract
The results of the analysis of the peculiarities of the clinical course of the disease and the effectiveness of therapy in patients with chronic obstructive pulmonary disease (COPD) with androgenic deficit. We examined 115 men aged from 42 to 62 years. Of these, 35 patients with COPD was diagnosed androgenic deficit. The study revealed a relationship between testosterone levels and quality of life. The use of hormone replacement therapy andriol contributed to improving the quality of life.
Научно-медицинский вестник Центрального Черноземья. 2015;(61):86-92
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THE USE OF RADICAL INTERVENTION AND THE USE OF RADICAL INTERVENTION AND PULSE OF ANOLYTE IN COMPLEX TREATMENT OF ACUTE PARAPROCTITIS
Andreev A.A., Demyanov A.N.
Abstract
The frequency of occurrence of the abscess is about 0.5% of the population in the Russian Federation, about 1% of all hospitalized in surgical hospitals or to 48% of patients with diseases of the rectum. The purpose of the study - improve results of complex treatment of patients with acute paraproctitis, based on the application of one-stage radical surgical intervention and the pulse of a purulent cavity with a solution of the neutral anolyte. During the execution of the study analyzed the results of treatment of 158 patients with acute paraproctitis, which were divided into control and two experimental groups. The control group consisted of 40 patients who after radical procedures (opening and drainage of purulent cavities, the elimination of the fistula orifice in the rectum) were assigned to daily treatment of purulent cavity with a solution of anolyte. 1st main group - 47 patients who only performed the autopsy, drainage and the hydro pulse of a purulent cavity anolyte. In the 2nd main group (71 patient) underwent radical intervention and a pulse of a purulent cavity neutral anolyte. To conduct a pulse of a purulent cavity was used the original device that is the source of high pressure (up to 7 atm.) allows to generate a pulsed flow of the antiseptic solution. The optimal method of complex treatment of acute abscess was performing radical surgery (excision of a crypt opening and drainage of the abscess) with pulse treatment of purulent cavity neutral anolyte (pH 7,0-7,2, ORP-+550-+800 mV) /2-I main group, the use of which allowed to reduce time of inflammation on average by 50%, the formation of granulation tissue and the epithelization - on 30-40%, to accelerate the relief of the intoxication syndrome and reduce the level of microbial contamination that significantly reduced the duration of hospitalization and rehabilitation.
Научно-медицинский вестник Центрального Черноземья. 2015;(61):93-97
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INFLUENCE OF VARIOUS OPTIONS OF HLORGEKSIDIN-DIOKSIDINOVOY OF MIX ON THE PATHOGENIC MICROFLORA
Bulynin B.B., Syretskikh V.A., Bondarenko E.V., Dementyeva L.M.
Abstract
The research of bactericidal action of new antiseptic composition which principal components are the known antiseptics - хлоргексидин and Dioxydinum was executed. The research was conducted by in vitro with participation of the most widespread causative agents of an intrahospital infection - E. coli, St. aureus, Pseud. aeruginosa. In an experiment various options of composition differing in concentration and a volume ratio of components were used.
Научно-медицинский вестник Центрального Черноземья. 2015;(61):98-101
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GROUP MEDICINES PHARMALOGICHESKAYA CARDIAC AND VASCULAR TOOLS: INFLUENCE ON THE CURRENT AND DISEASE OUTCOMES AT PATIENTS WITH THE CHRONIC OBSTRUCTIVE PULMONARY DISEASE
Malysh E.Y., Drobysheva E.S., Ovsyannikov E.S., Tokmachev R.E., Chernov A.V., Volokitin A.N., Titova L.A.
Abstract
Chronic obstructive pulmonary disease - the disease which is characterized by a persistention of a low-intensive systemic inflammation and, respectively, having close connection with cardiovascular diseases. Thus, influence of basic groups of cardiovascular medicines on a current and clinical outcomes of HOBL is represented urgent: β-blockers, inhibitors of angiotenzinprevrashchayushchy enzyme (IAPF) and blockers of receptors to angiotensin (SCONCE), statin. Keywords: chronic obstructive pulmonary disease, cardiovascular diseases.
Научно-медицинский вестник Центрального Черноземья. 2015;(61):102-107
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COMPLEX INFLUENCE OF LIQUID WITH THE NEGATIVE REDOX POTENTIAL ON SEPARATE INDICATORS OF BULK ANALYSIS OF BLOOD AT PATIENTS WITH GONARTROZ 3-4 DEGREES IN THE EARLY PERIOPERATSIONNY PERIOD
Tokar A.A., Samodai V.G., Reznikov K.M., Atyakshin D.A.
Abstract
In work indexes of the bulk analysis of blood (BAB) at introduction of liquid with the negative redox potential (RP) by the patient with deforming gonartrozy in the perioperatsionny period are investigated. Liquid intake, with the negative OVP increases sizes of the following indexes of OAK a little: HGB, MCV, MCH, MCHC, PLT, and also lowers such important parameters as - SOE, NEUT that is especially expressed at the dosed their appointment. At the dosed oral administration of liquid with the negative OVP at the rate of 2 ml of a catholyte on 1 kg of body weight of the patient the quantity of authentically changed indicators of OAK increases by 12 days after performing surgery.
Научно-медицинский вестник Центрального Черноземья. 2015;(61):108-111
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CHILDREN AGE AND SEX DIFFERENCES OF BLOOD PRESSURE IN THE VORONEZH REGION
Zhdanova O.A., Sitnikova V.P.
Abstract
The article presents the results of statistical analysis of the blood pressure of 1124 boys and 1185 girls 7-16 years old living in the Voronezh region in 2011-2014. Systolic blood pressure of the boys prevailed over systolic blood pressure values of the girls at all ages groups. The minimal differences were at the age of 10 years old, maximal - at 15 and 16 years old (р0,005). The average measurements of diastolic blood pressure of girls at 8-10 years old and 13 were higher but at the age of 14- lower than the same numbers at boys group. It was discovered a small decrease in the measures of diastolic blood pressure at 15-16 years old girls group in comparison with the younger girls group.
Научно-медицинский вестник Центрального Черноземья. 2015;(61):112-116
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