No 54 (2013)

Articles
PHARMACOGNOSTIC RESEARCH OF AERIAL PARTS OF THE PELARGONIUM ZONAL (PELARGONIUM ZONALE L. HER.)
Bulatova I.A., Yushkova T.A.
Abstract
The main diagnostic signs of the aerial parts of the Pelargonium zonal (Pelargonium zonale L. Her., fam. Geraniaceae), the presence of flavonoids, substances of protein nature and phenol carbonic acids are revealed. At the received phytopreparation existence of the expressed hypoglycemic activity is revealed. Key words: Pelargonium zonale, flavonoids, substances of protein nature, phenol carbonic acids, hypoglycemic activity.
Научно-медицинский вестник Центрального Черноземья. 2013;(54):1-8
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RAK PREDSTATEL'NOY ZhELEZY U MOLODYKh MUZhChIN V ALTAYSKOM KRAE
Ganov D.I., Lazarev A.F.
Abstract
Рeзюме. Была ретроспективно отобрана группа - 195 мужчин больных раком предстательной железы с впервые установленным диагнозом в возрасте до 55 лет. РПЖ у мужчин молодого возраста до 55 лет у 84(43,0%) мужчин выявлен в запущенной форме с отдаленными метастазами. У 53(27,2%) пациентов был диагностирован рак третьей стадии. У 51(26,2%) пациента рак предстательной железы второй стадии и только у 7(3,61%) рак первой стадии. Около 24,0% мужчин молодого возраста с установленным раком предстательной железы отмечали факт наличия злокачественной болезни у своих близких родственников. Удельный вес мужчин с установленным раком предстательной железы до 55 лет в структуре ЗН предстательной железы составил 12,0%. В молодом возрасте рак предстательной железы у мужчин имеет агрессивное течение. Рак предстательной железы у мужчин Алтайского края в возрасте до 55 лет чаще диагностируется в запущенной стадии с отдаленными метастазами и характеризуется низкой продолжительностью жизни.
Научно-медицинский вестник Центрального Черноземья. 2013;(54):9-11
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DOPAMINE AGONIST AND LEVODOPA IN THE TREATMENT OF EXTRAPYRAMIDAL DISEASES
Zolotarev O.V., Karpova O.Y.
Abstract
Was Compared the effects of levodopa and dopamine receptor agonists (DRAs) on patients with Parkinson's disease (PD) and parkinsonian syndrome . Levodopa were effective in both cases, but more in the treatment of PD. Using DRAs is effective in the early stages of PD, at later stages of PD and parkinsonism syndrome effects were not noted .
Научно-медицинский вестник Центрального Черноземья. 2013;(54):12-17
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CORRELATION BETWEEN IMMUNE STATUS INDICES IN PATIENTS WITH MULTIPLE SCLEROSIS
Lutsky M.A., Lushnikova Y.P., Smelyanets M.A.
Abstract
The article gives an analysis of a number of parameters indicating that there cannot be any isolated disorders in a human organism. Immune system ab-normalities are closely related to nervous and endocrine regulations of func-tions. Immunopathology, in its turn, is associated with metabolic disorders, which finally lead to additional complications. There exists a real capacity in a patient’s organism to influence the immune status by means of biochemical pa-rameters and vice versa. All these aspects are analyzed in the given article.
Научно-медицинский вестник Центрального Черноземья. 2013;(54):18-24
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ANALYSIS OF PROTEIN AND LIPID FREE-RADICAL OXIDATION PROCESSES IDENTIFYING OXIDATIVE STRESS IN DIFFERENT CLINICAL FORMS OF MULTIPLE SCLEROSIS
Lutsky M.A., Razinkin K.A., Lushnikova Y.P., Smelyanets M.A.
Abstract
The article gives a detailed analysis of protein and lipid free-radical oxidation processes identifying oxidative stress in Primary Progressive Multiple Sclerosis (PPMS) and Secondary Progressive Multiple Sclerosis (SPMS). The findings obtained in the course of the study make it possible to verify the presence of two factors in the oxidative stress development, namely: the intensification of free-radical oxidation (FRO) processes and the functional imbalance in the enzymatic and nonenzymatic segments of the antioxidant defense system (ADS) in PPMS and SPMS. The understanding of the complex pathogenesis of Multiple Sclerosis guarantees an effective and potentially productive therapy for such a severe disease of the nervous system.
Научно-медицинский вестник Центрального Черноземья. 2013;(54):25-33
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METABOLIC INDICES DYNAMICS VERIFYING THE CONTINUITY OF PATHOLOGIC PROCESS PROGRESSION IN MULTIPLE SCLEROSIS
Lutsky M.A., Smelyanets M.A.
Abstract
The article gives an analysis of the metabolic dynamics verifying protein and lipid free-radical oxidation (FRO) intensification and a functional imbalance in the enzymatic and nonenzymatic segments of the antioxidant defense system (ADS), which identifies the presence of oxidative stress - one of the components of the complex pathogenesis of Multiple Sclerosis. The understanding of the complex pathogenesis of all clinical forms and phases of Multiple Sclerosis makes it possible to make a case for an effective pathogenetic therapy in the evidence-based practice, which is considered to be a basis for improvement of life quality of patients suffering from this serious disorder.
Научно-медицинский вестник Центрального Черноземья. 2013;(54):34-39
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THE INFLUENCE OF THE TEMPERATURE FACTORS ON THE MULTIPLE SCLEROSIS CLINICAL PICTURE
Protasov I.S., Pozhidaeva Y.A., Matsnev A.O.
Abstract
It is known that the hot weather and hot tub worsen the condition of patients with multiple sclerosis (MS), in contrast mild temperatures leads to a smoothing of the individual symptoms. Study of the influence of thermal factors on the clinical picture of MS advisable considering the pathomorphosis diseases at the present stage of development of neurology and significant progress in the treatment and diagnosis of diseases of the nervous system. Having data about a possible change in clinical and course of MS under the influence of temperature factors, we can use all our opportunities to improve MS-patients quality of life management.
Научно-медицинский вестник Центрального Черноземья. 2013;(54):40-43
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TO NECESSITY OF USING OF THE MARK-RATING TECHNOLOGY OF ACHIEVEMENT EVALUATION OF THE INTERNS IN PROFESSIONAL EDUCATION SYSTEM AFTER-UNIVERSITY
Soloveva A.L., Selina O.B.
Abstract
The rating system provides continuous monitoring of the knowledge of interns in all educational levels, test results integration from one stage to another, discipline ranking definition of the intern, and in the future - for the entire period of study. The introduction of the point-rating system, which estimates learning and cognitive activity, should be combined with effective teaching management at the level of interaction interns and teachers in the study of dental disciplines that creates professional competence of the future specialists. Reforming of the traditional system of evaluation is necessary, and as one of its alternatives the point-rating technology of the assessment study and extracurricular achievements of interns can be offered, which is really effective, very straightforward, has undeniable advantages for teachers and interns, and can evolve over time.
Научно-медицинский вестник Центрального Черноземья. 2013;(54):44-50
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INFLUENCE НУРОХYA ON OXIDATIVE STRESS AND INDICATORS COGNITIVE DISORDES
Bolotskih V.I., Chernyh Y.N.
Abstract
Was the purpose of exploring the dynamics of some indicators of oxidative stress and cognitive disorders in 80 patients with chronic obstructive pulmonary disease (COPD) with essential hypertension (EH), it is shown that at lower hemoglobin oxygen saturation up to 94,10 ± 0,85%, cognitive impairment observed average severity, with the prevalence of disorders of orientation, perception, attention and memory.
Научно-медицинский вестник Центрального Черноземья. 2013;(54):51-56
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METHOD OF MODELING OF CHRONIC OSTEOMYELITIS
Mikulich E.V., Glukhov A.A., Ostroushko A.P.
Abstract
Currently, many methods for modeling chronic osteomyelitis are known. All of them can be divided into four groups: the first group - hematogenous infection of the animal, the second group - additional bone irritation and introduction of the microbial flora into the organism, the third - the introduction of microbial flora against the background of sensitization of the organism and the fourth - the combination of infection of the organism with additional irritation of the nervous system. In this study, an experimental model of chronic osteomyelitis has been developed that meets all modern requirements.
Научно-медицинский вестник Центрального Черноземья. 2013;(54):57-61
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TO THE PROBLEM OF PREDICTING THE RISK FACTORS OF THE DEVELOPMENT OF REPEATED ISCHEMIC STROKES IN YOUNG AND MIDDLE AGE PERSONS
Dutova T.I., Skorokhodov A.P.
Abstract
The problem of repeated ischemic strokes is urgent in modern neurology. The occurrence of repeated ischemic strokes can be influenced by many factors, each of which is individually significant for the patient. We have developed a method that allows to predict the individual significance of the contribution of various risk factors for the development of FDI in young and middle-aged people, their impact on the dynamics of recovery, clinical course of the disease.
Научно-медицинский вестник Центрального Черноземья. 2013;(54):62-66
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OPTIMIZATION OF THERAPY OF INFECTIOUS MONONUCLEOSIS EPHTEIN-BARR OF VIRUS ETIOLOGY IN CHILDREN
Kotlova V.B., Kokoreva S.P.
Abstract
According to modern data, infectious mononucleosis (MI) is a polyethiologic disease. In its occurrence, cytomegalovirus, herpes simplex virus type 1 and type 2, human herpesvirus type 6, and their association with the leading role of the Epstein-Barr virus (EBV) are involved. To date, VEB-associated MI is considered as one of the forms of the Epstein-Barr virus infection (EBVI), which according to the literature data accounts for 5-18% of all diseases of EBVI-etiology. We analyzed the clinical efficacy of various antiviral drugs in the complex treatment of infectious mononucleosis depending on the form of EBVI.
Научно-медицинский вестник Центрального Черноземья. 2013;(54):67-74
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MEDICAL AND SOCIAL ASPECTS OF HEALTH OF SCHOOLBOYS OF ADOLESCENT AGE AND WAYS OF OPTIMIZATION OF MEDICAL CARE
Lavlinskaya L.I., Malyutina M.A., Sitnikova L.N.
Abstract
The level of health of modern schoolchildren determines the high prevalence of diseases, disorders in neuropsychic and physical development, a significant acute incidence. A negative factor is the increasing prevalence of the most destructive behaviors: smoking, drinking alcohol, drugs, risk-related sexual behavior. One of the leading causes of progressive deterioration in health is the ineffectiveness of many preventive and corrective measures to preserve and strengthen the health of children.
Научно-медицинский вестник Центрального Черноземья. 2013;(54):75-78
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PREDICTIONAL MODEL OF EVALUATION OF RISK OF COMPLICATIONS WITH MINYVASIVE SURGICAL INTERVENTIONS ON THE LIVER
Ninikashvili L.V.
Abstract
Therapeutic and diagnostic interventions on the liver under ultrasound control have recently become widespread. In Russia, at least 12,000 such operations are produced annually (Novomlinsky VV, 2008). Diagnostic interventions are represented mainly by percutaneous biopsy of focal formations, therapeutic ones by puncture-draining operations in liquid formations, and by minimally invasive methods of treatment of primary and metastatic liver cancer, including radio-frequency ablation, cryo-exposure and introduction of ethanol. The advantages of minimally invasive operations under ultrasound control are low traumatism, cosmetic effect, the possibility of performing them under local anesthesia and economy.
Научно-медицинский вестник Центрального Черноземья. 2013;(54):79-83
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ORGANIZATION OF SERVICE OF SOCIAL-PSYCHOLOGICAL SUPPORT OF DEVELOPMENT OF CHILDREN REMAINED WITHOUT PARENTAL TRAINING
Shabanova L.A.
Abstract
A child who is brought up in a specialized home has certain characteristics in the psychic and emotional-personal sphere, in interpersonal relationships with peers and adults. To create optimal conditions for the development of a socially-adapted personality in the child's home, a psycho-pedagogical and medical-social support service was created.
Научно-медицинский вестник Центрального Черноземья. 2013;(54):84-88
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