Medical Scientific Bulletin of Central Chernozemye (Naučno-medicinskij vestnik Centralʹnogo Černozemʹâ)Medical Scientific Bulletin of Central Chernozemye (Naučno-medicinskij vestnik Centralʹnogo Černozemʹâ)1990-472XФедеральное государственное бюджетное образовательное учреждение высшего образования "Воронежский государственный медицинский университет имени Н.Н. Бурденко" Министерства здравоохранения Российской Федерации894210.18499/1990-472X-2023-1-91-49-58REVIEW OF SURFACTANT DELIVERY STRATEGIES IN NEONATOLOGICAL PRACTICEIppolitovaLyudmila Ivanovna<pre id="tw-target-text" class="tw-data-text tw-text-large tw-ta" dir="ltr" data-placeholder="Перевод"><span class="Y2IQFc" lang="en">Doctor of Medical Sciences, Head of the Department of Neonatology and Pediatrics</span></pre>liippolitova@okb-vrn.ruKorotaevaNatalia Vladimirovna<pre id="tw-target-text" class="tw-data-text tw-text-large tw-ta" dir="ltr" data-placeholder="Перевод"><span class="Y2IQFc" lang="en">Candidate of Medical Sciences, Associate Professor of the Department of Neonatology and Pediatrics</span></pre>korotaeva.nv@mail.ruPershinaElena Sergeevna<p>Assistant of the Department of Neonatology and Pediatrics</p>pershina.neo@gmail.comPanichevKonstantin Vladimirovich<p>Candidate of Medical Sciences, Assistant of the Department of Neonatology and Pediatrics</p>mail@vokb1.zdrav36.ruLobanovaOlga Alekseevnalobanovashreya@yandex.ruDilbaryanArtem Aleksandrovichdilbaryan.aa@gmail.comVoronezh State Medical University2903202324149580105202311052023Copyright © 2023, Medical Scientific Bulletin of Central Chernozemye (Naučno-medicinskij vestnik Centralʹnogo Černozemʹâ)2023<p>Administration of surfactant by minimally invasive techniques that promote spontaneous breathing may be safer and more effective than administration with endotracheal intubation and mechanical ventilation. At present, the use of INSURE and LISA/MIST methods is well researched and widely used, their effectiveness has been largely proven and beyond doubt. However, current trends towards greater use of non-invasive respiratory support in surfactant-deficient preterm infants have created a demand for similar non-invasive methods of administering exogenous surfactant, one of which is the potentially promising method of inhaled delivery of a substance to the lungs using a nebulizer.</p>respiratory distress syndrome of newbornsprematuresurfactantINSUREnCPAPLISAMISTTake CareSALSA.респираторный дистресс-синдром новорожденныхнедоношенныйсурфактантINSUREnCPAPLISAMISTTake CareSALSA.1.Евтюков Г.М. Синдром дыхательных расстройств у новорожденных // Проблемы формирования здоровья человека в перинатальном периоде и в детском возрасте: Сб. науч. тр. под ред. Н.П. Шабалова. — СПб.: Изд-во «Ольга», 2004. — С. 172-178.2.Sweet DG, Carnielli V, Greisen G, Hallman M, Ozek E, Plavka R, et al. 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