Medical Scientific Bulletin of Central Chernozemye (Naučno-medicinskij vestnik Centralʹnogo Černozemʹâ)Medical Scientific Bulletin of Central Chernozemye (Naučno-medicinskij vestnik Centralʹnogo Černozemʹâ)1990-472XФедеральное государственное бюджетное образовательное учреждение высшего образования "Воронежский государственный медицинский университет имени Н.Н. Бурденко" Министерства здравоохранения Российской Федерации894010.18499/1990-472X-2023-1-91-6-10ROLE OF MICROBIOLOGICAL MONITORING IN ALMATY MULTIDISCIPLINARY HOSPITALZinbayFatima A.zinbay.zinbay2@mail.ruNuralimMagzhan N.dok_make@mail.ruhttps://orcid.org/0000-0003-2591-0345DyussengaliyevaSamal T.dyussengaliyeva@list.ruKazakh National Medical University named after S.D. Asfendiyarov290320232416100105202311052023Copyright © 2023, Medical Scientific Bulletin of Central Chernozemye (Naučno-medicinskij vestnik Centralʹnogo Černozemʹâ)2023<p>Microbiological monitoring is the most important component of the epidemiological safety of the medical and diagnostic process, an integral part of the process of providing epidemiological surveillance for infections associated with the provision of medical care [1].</p> <p>Purpose. Determine the effectiveness of microbiological monitoring of patients, study the microbiological spectrum and resistance of microflora to antibiotics with the study of the antibiotic graph.</p> <p>Materials and methods. Data on antimicrobial sensitivity of microorganism strains isolated from the wound compartment (55 patients) and sputum (258 patients) were retrospectively analyzed. The microbial landscape was studied, based on the results of records in disease histories for six months (October 2021 - April 2022). Microbiological studies were performed on the basis of the City Clinical Hospital No. 4 in Almaty according to the approved regulatory documents [5]. Results. Thus, the results of our study showed a high percentage of excretion of gram-positive flora in sputum and wound separation. In most cases, microflora was sensitive to moxifloxacin, levofloxacin and gentamicin with different degrees of severity. There was a difference in the resistance of the sputum flora to erythromycin, and the microflora of the wound secretible to oxacillin. This indicates the need to make changes in the tactics of administering and treating these patients in accordance with the principles of rational use of antimicrobials [6].</p> <p>Conclusion. Rational antimicrobial therapy can be carried out with timely and guaranteed receipt of information on the sensitivity of microorganisms to antimicrobial drugs. The spread of antibiotic-resistant microorganisms in medical organizations significantly reduces the effectiveness of antibacterial therapy and is associated with the threat of the spread of ubiquitous strains. Targeted observations of the resistance of infectious agents to these drugs represent one of the effective ways to prevent antibiotic resistance [1].</p>microbiological monitoringantibiotic resistancepolyresistance of pathogens.микробиологический мониторингантибиотикорезистентностьполирезистентность возбудителей.1.Микробиологический мониторинг антимикробной резистентности потенциальных возбудителей инфекций кровотока / А.С. Захватова, М.Г. Дарьина, Ю.С. Светличная, и др. // Инфекция и иммунитет, 2022. – Т.12. – С. 185–192.2.Antimicrobial resistance surveillance in Europe 2022.3.European strategic action plan on antibiotic resistance. Copenhagen: WHO Regional Office for Europe; 20114.European strategic action plan on antibiotic resistance. Sixty-first Regional Committee for Europe: Baku, 12–15 September 20115.Приказ Министра здравоохранения Республики Казахстан от 15 октября 2021 года № ҚР ДСМ-105. «Об утверждении Санитарных правил "Санитарно-эпидемиологические требования к лабораториям, использующим потенциально опасные химические вещества"»6.Микробиологические показатели пациентов с подтвержденной инфекцией COVID-19 / Н. М. Бисенова // Наука и Здравоохранение, 2020. – Т. 22, № 6.7.Микробиологический пейзаж отделения трансплантации почки / А.Б. Зулькарнаев, А.В. Ватазин, М. Крстич // 2013