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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" article-type="research-article" dtd-version="1.1d1" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher">Medical Scientific Bulletin of Central Chernozemye (Naučno-medicinskij vestnik Centralʹnogo Černozemʹâ)</journal-id><journal-title-group><journal-title>Medical Scientific Bulletin of Central Chernozemye (Naučno-medicinskij vestnik Centralʹnogo Černozemʹâ)</journal-title></journal-title-group><issn publication-format="electronic">1990-472X</issn><publisher><publisher-name>Федеральное государственное бюджетное образовательное учреждение высшего образования "Воронежский государственный медицинский университет имени Н.Н. Бурденко" Министерства здравоохранения Российской Федерации</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">7994</article-id><article-id pub-id-type="doi">10.18499/1990-472X-2022-0-90-5-9</article-id><article-categories><subj-group subj-group-type="heading"><subject>Original Article</subject></subj-group></article-categories><title-group><article-title>INFLUENCE OF ANTIBIOTIC RESISTANCE ON THE STRUCTURE            ECONOMIC COSTS OF COVID-19 PHARMACOTHERAPY</article-title></title-group><contrib-group><contrib contrib-type="author"><name name-style="western"><surname>Somova</surname><given-names>M. N</given-names></name><bio></bio><email>-</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Radchenko</surname><given-names>D. S</given-names></name><bio></bio><email>-</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Kotelnikova</surname><given-names>T. E</given-names></name><bio></bio><email>-</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Mubarakshina</surname><given-names>O. A</given-names></name><bio></bio><email>-</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Elfimova</surname><given-names>E. V</given-names></name><bio></bio><email>-</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff id="aff-1">Voronezh State Medical University</aff><aff id="aff-2">"Clinical Hospital" RZD-Medicine "Voronezh"</aff><pub-date date-type="epub" iso-8601-date="2022-12-15" publication-format="electronic"><day>15</day><month>12</month><year>2022</year></pub-date><issue>90</issue><fpage>5</fpage><lpage>9</lpage><history><pub-date date-type="received" iso-8601-date="2023-01-22"><day>22</day><month>01</month><year>2023</year></pub-date></history><permissions><copyright-statement>Copyright © 2022, Medical Scientific Bulletin of Central Chernozemye (Naučno-medicinskij vestnik Centralʹnogo Černozemʹâ)</copyright-statement><copyright-year>2022</copyright-year></permissions><abstract>The COVID-19 pandemic has proved to be a serious test for public health, including from an economic point of view. Conflicting data on the treatment options for COVID-19 infection have been reflected in ever-changing pharmacotherapy recommendations. One of the problems was the uncontrolled use of medicines by the population for the treatment of a new coronavirus infection. Often, the unjustified use of antibacterial agents has led to an escalation of the problem of antibiotic resistance of microorganisms. In this work, a pharmacoeconomic assessment of the costs of purchasing medicines for the treatment of patients with a new coronavirus infection in the "Clinical Hospital" RZD-Medicine "Voronezh" for 2021 and determining the share of costs for the purchase of antimicrobial agents was carried out. In addition, we analyzed the spectrum of pathogens isolated from patients of the covid hospital and assessed their sensitivity to the main groups of antibacterial agents.</abstract><kwd-group xml:lang="en"><kwd>pharmacoeconomic evaluation</kwd><kwd>new coronavirus infection COVID-19</kwd><kwd>antibiotic resistance</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>фармакоэкономическая оценка</kwd><kwd>новая коронавирусная инфекция COVID-19</kwd><kwd>антибиотикорезистентность</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Кашепов А.В. Факторы и экономические последствия пандемии коронавируса // Вестник Алтайской академии экономики и права. - 2021. - №2. - С. 38-45.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Сомова М.Н., Мубаракшина О.А., Алаторцева А.А., Ким Н.В., Котельникова Т.Е., Старых Л.Н. Фармакоэкономическая оценка различных схем терапии новой коронавирусной инфекции COVID - 19 в условиях стационара // В сборнике: Актуальные вопросы лекарственного обеспечения и контроль качества препаратов. Сборник трудов научно-практической конференции. - Воронеж, 2021. - С. 35-39.</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Рогова И.В., Жидкова Е.А., Попова И.А., Заборовский А.В., Гуревич К.Г. Фармакоэкономические аспекты лечения COVID-19 // Фармакоэкономика. Современная фармакоэкономика и фармакоэпидемиология. - 2021. - Том: 14, №3. - C. 357-364.</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>Временные методические рекомендации «Профилактика, диагностика и лечение новой коронавирусной инфекции (COVID-19)». Версия 15 (22.02.2022).</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>ВОЗ. В новом докладе содержится призыв к срочным действиям по предупреждению кризиса, вызванного устойчивостью к противомикробным препаратам. Адрес: https://www.who.int/ru/news/item/29-04-2019-new-report-calls-for-urgent-action-to-avert-antimicrobial-resistance-crisis</mixed-citation></ref><ref id="B6"><label>6.</label><mixed-citation>Акимкин В.Г., Тутельян А.В., Шулакова Н.И., Воронин Е.М. Пандемия COVID-19: новый виток нарастания антибиотикорезистентности // Инфекционные болезни. - 2021- Т. 19, №3. - С. 133-138.</mixed-citation></ref><ref id="B7"><label>7.</label><mixed-citation>Liu C, Wen Y, Wan W, Lei J, Jiang X. Clinical characteristics and antibiotics treatment in suspected bacterial infection patients with COVID-19 // Int Immunopharmacol. - 2021 Jan; 90:107157. DOI: 10.1016/j.intimp.2020.107157.</mixed-citation></ref><ref id="B8"><label>8.</label><mixed-citation>Нургожин Т.С., Ведерникова О.О., Кучаева А.В. и др. К вопросу об использовании ABC и VEN анализов в научных исследованиях и практическом здравоохранении. // Клиническая фармакология и терапия. - 2004. - №5. - C. 27-29.</mixed-citation></ref></ref-list></back></article>
