Medical Scientific Bulletin of Central Chernozemye (Naučno-medicinskij vestnik Centralʹnogo Černozemʹâ)Medical Scientific Bulletin of Central Chernozemye (Naučno-medicinskij vestnik Centralʹnogo Černozemʹâ)1990-472XФедеральное государственное бюджетное образовательное учреждение высшего образования "Воронежский государственный медицинский университет имени Н.Н. Бурденко" Министерства здравоохранения Российской Федерации790910.18499/1990-472X-2022-0-89-57-69Original ArticleHYPOLIPIDEMIC ACTIVITY OF THE MEDICINAL PLANT MOMORDICA HARANTIASamadovB. ShDep. of Pharmacology and Clinical Pharmacology-ZhalilovF. SDep. of Pharmaceutical Production Organization and Quality Management-ZhalilovaF. SDep. of Pharmacology and Clinical Pharmacology-Bukhar State Medical Institute named after Abu Ali ibn SinoTashkent Pharmaceutical Institute1512202289576928102022Copyright © 2022, Medical Scientific Bulletin of Central Chernozemye (Naučno-medicinskij vestnik Centralʹnogo Černozemʹâ)2022From ancient times to the present day, medicinal plants have been potential and useful for the treatment of a number of diseases and disorders. The main reason for this is that medicinal plants do not have any side effects. One of the most common tropical vegetables is Momordica charantia, it has been used in various Asian traditional medicines [1]. The plant Momordica charantia Linn., known as bitter gourd, belongs to the pumpkin family. It is cultivated throughout India, Malaysia, China, Tropical Africa and America. Earlier statements have shown that its bitter fruits have carminative, aphrodisiac and anthelmintic properties, are used for syphilis, rheumatism, diseases of the spleen and ophthalmia. It is also useful for hemorrhoids, leprosy, jaundice and is used as an anthelmintic. This review highlights the main pharmacological uses of Momordica charantia [2]. It has been suggested that Momordica charantia, also known as bitter melon, had an effect on lowering blood glucose levels through various forms and extracts from the plant. For many years, commercially available preparations containing bitter melon have been appearing on the market, despite limitations in available clinical trials. The conducted clinical study demonstrates a variety of results on the effect of Momordica charantia on glycemic control, mostly without demonstrating statistically significant differences. Monitoring is vital given the reported side effects and precautions needed for specific individuals, as well as unknown interactions of herbal medications or herbal foods that may disrupt the overall treatment plan. At the same time, the results obtained as a result of the studies give only an idea of the potential benefits that Momordica charantia offers in the prevention and treatment of type II diabetes, as well as microvascular complications, instead of a definite conclusion [3].Momordica charantiaMomordica charantiabitter melonbalsamic pearkarelapumpkinBukhara regionRepublic of Uzbekistanphytochemicalsphytochemical componentsterpenoidsproteinssterolsfatty acidsvolatile componentsnutritional usemedicinal propertiesantidiabetic propertieshypolipidemic activityмомордика чарантиягорькая дынябальзамическая грушакарелатыквенныефитохимические веществафитохимические компонентытерпеноидыбелкистериныжирные кислотылетучие компонентыпищевое применениелечебные свойстваантидиабетическая свойствагиполипидемическая активностьБухарская областьРеспублика Узбекистан1.Kumar, D. S., Sharathnath, K. V., Yogeswaran, P., Harani, A., Sudhakar, K., Sudha, P., Banji, D. (2010). 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